Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| B | 0003824 | molecular_function | catalytic activity |
| C | 0003824 | molecular_function | catalytic activity |
| D | 0003824 | molecular_function | catalytic activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | GLY7 |
| A | ASP62 |
| A | ILE63 |
| A | LEU81 |
| A | ALA82 |
| A | ALA83 |
| A | PRO85 |
| A | ASN101 |
| A | VAL105 |
| A | ILE124 |
| A | SER125 |
| A | GLY10 |
| A | THR126 |
| A | TYR149 |
| A | LYS153 |
| A | TYR176 |
| A | VAL179 |
| A | ARG185 |
| A | MET188 |
| A | UGA402 |
| A | UGB403 |
| A | HOH517 |
| A | PHE11 |
| A | HOH623 |
| A | HOH639 |
| A | HOH654 |
| A | ILE12 |
| A | ASP32 |
| A | HIS33 |
| A | PHE34 |
| A | ILE35 |
| A | LYS43 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | binding site for residue UGA A 402 |
| Chain | Residue |
| A | PRO85 |
| A | ARG88 |
| A | THR126 |
| A | SER127 |
| A | SER128 |
| A | TYR149 |
| A | TYR176 |
| A | PHE177 |
| A | THR178 |
| A | ARG185 |
| A | MET188 |
| A | ALA189 |
| A | ARG192 |
| A | THR204 |
| A | ILE205 |
| A | PHE206 |
| A | GLN211 |
| A | ARG213 |
| A | ILE250 |
| A | GLU276 |
| A | NAD401 |
| A | UGB403 |
| A | HOH535 |
| A | HOH554 |
| A | HOH558 |
| A | HOH563 |
| A | HOH576 |
| site_id | AC3 |
| Number of Residues | 28 |
| Details | binding site for residue UGB A 403 |
| Chain | Residue |
| A | PRO85 |
| A | GLY86 |
| A | VAL87 |
| A | ARG88 |
| A | THR126 |
| A | SER127 |
| A | SER128 |
| A | TYR149 |
| A | TYR176 |
| A | THR178 |
| A | ARG185 |
| A | MET188 |
| A | ALA189 |
| A | ARG192 |
| A | THR204 |
| A | ILE205 |
| A | PHE206 |
| A | GLN211 |
| A | ARG213 |
| A | ILE250 |
| A | GLU276 |
| A | NAD401 |
| A | UGA402 |
| A | HOH535 |
| A | HOH558 |
| A | HOH563 |
| A | HOH576 |
| A | HOH728 |
| site_id | AC4 |
| Number of Residues | 32 |
| Details | binding site for residue NAD B 401 |
| Chain | Residue |
| B | ALA82 |
| B | ALA83 |
| B | ASN101 |
| B | VAL105 |
| B | ILE124 |
| B | SER125 |
| B | THR126 |
| B | TYR149 |
| B | LYS153 |
| B | TYR176 |
| B | THR178 |
| B | VAL179 |
| B | ARG185 |
| B | MET188 |
| B | UGA402 |
| B | UGB403 |
| B | HOH526 |
| B | HOH578 |
| B | HOH592 |
| B | HOH618 |
| B | GLY7 |
| B | GLY10 |
| B | PHE11 |
| B | ILE12 |
| B | ASP32 |
| B | HIS33 |
| B | PHE34 |
| B | ILE35 |
| B | LYS43 |
| B | ASP62 |
| B | ILE63 |
| B | LEU81 |
| site_id | AC5 |
| Number of Residues | 28 |
| Details | binding site for residue UGA B 402 |
| Chain | Residue |
| B | PRO85 |
| B | ARG88 |
| B | THR126 |
| B | SER127 |
| B | SER128 |
| B | TYR149 |
| B | TYR176 |
| B | PHE177 |
| B | THR178 |
| B | ARG185 |
| B | MET188 |
| B | ALA189 |
| B | ARG192 |
| B | THR204 |
| B | ILE205 |
| B | PHE206 |
| B | GLN211 |
| B | ARG213 |
| B | ILE250 |
| B | GLU276 |
| B | NAD401 |
| B | UGB403 |
| B | HOH528 |
| B | HOH531 |
| B | HOH539 |
| B | HOH566 |
| B | HOH570 |
| B | HOH600 |
| site_id | AC6 |
| Number of Residues | 27 |
| Details | binding site for residue UGB B 403 |
| Chain | Residue |
| B | PRO85 |
| B | GLY86 |
| B | ARG88 |
| B | THR126 |
| B | SER127 |
| B | SER128 |
| B | TYR149 |
| B | TYR176 |
| B | THR178 |
| B | ARG185 |
| B | MET188 |
| B | ALA189 |
| B | ARG192 |
| B | THR204 |
| B | ILE205 |
| B | PHE206 |
| B | GLN211 |
| B | ARG213 |
| B | ILE250 |
| B | GLU276 |
| B | NAD401 |
| B | UGA402 |
| B | HOH528 |
| B | HOH531 |
| B | HOH539 |
| B | HOH566 |
| B | HOH600 |
| site_id | AC7 |
| Number of Residues | 33 |
| Details | binding site for residue NAD C 401 |
| Chain | Residue |
| C | GLY7 |
| C | GLY10 |
| C | PHE11 |
| C | ILE12 |
| C | ASP32 |
| C | HIS33 |
| C | PHE34 |
| C | ILE35 |
| C | LYS43 |
| C | GLU61 |
| C | ASP62 |
| C | ILE63 |
| C | LEU81 |
| C | ALA82 |
| C | ALA83 |
| C | ASN101 |
| C | VAL105 |
| C | ILE124 |
| C | SER125 |
| C | THR126 |
| C | TYR149 |
| C | LYS153 |
| C | TYR176 |
| C | THR178 |
| C | VAL179 |
| C | ARG185 |
| C | MET188 |
| C | UGA402 |
| C | UGB403 |
| C | HOH522 |
| C | HOH572 |
| C | HOH577 |
| C | HOH590 |
| site_id | AC8 |
| Number of Residues | 27 |
| Details | binding site for residue UGA C 402 |
| Chain | Residue |
| C | PRO85 |
| C | ARG88 |
| C | THR126 |
| C | SER127 |
| C | SER128 |
| C | TYR149 |
| C | TYR176 |
| C | PHE177 |
| C | THR178 |
| C | ARG185 |
| C | MET188 |
| C | ALA189 |
| C | ARG192 |
| C | THR204 |
| C | ILE205 |
| C | PHE206 |
| C | GLN211 |
| C | ARG213 |
| C | ILE250 |
| C | GLU276 |
| C | NAD401 |
| C | UGB403 |
| C | HOH525 |
| C | HOH562 |
| C | HOH569 |
| C | HOH589 |
| C | HOH602 |
| site_id | AC9 |
| Number of Residues | 27 |
| Details | binding site for residue UGB C 403 |
| Chain | Residue |
| C | PRO85 |
| C | GLY86 |
| C | ARG88 |
| C | THR126 |
| C | SER127 |
| C | SER128 |
| C | TYR149 |
| C | TYR176 |
| C | THR178 |
| C | ARG185 |
| C | MET188 |
| C | ALA189 |
| C | ARG192 |
| C | THR204 |
| C | ILE205 |
| C | PHE206 |
| C | GLN211 |
| C | ARG213 |
| C | ILE250 |
| C | GLU276 |
| C | NAD401 |
| C | UGA402 |
| C | HOH525 |
| C | HOH562 |
| C | HOH569 |
| C | HOH589 |
| C | HOH634 |
| site_id | AD1 |
| Number of Residues | 33 |
| Details | binding site for residue NAD D 401 |
| Chain | Residue |
| D | GLY7 |
| D | GLY10 |
| D | PHE11 |
| D | ILE12 |
| D | ASP32 |
| D | HIS33 |
| D | PHE34 |
| D | ILE35 |
| D | LYS43 |
| D | GLU61 |
| D | ASP62 |
| D | ILE63 |
| D | LEU81 |
| D | ALA82 |
| D | ALA83 |
| D | ASN101 |
| D | VAL105 |
| D | ILE124 |
| D | SER125 |
| D | THR126 |
| D | TYR149 |
| D | LYS153 |
| D | TYR176 |
| D | THR178 |
| D | VAL179 |
| D | ARG185 |
| D | MET188 |
| D | UGA402 |
| D | UGB403 |
| D | HOH526 |
| D | HOH582 |
| D | HOH595 |
| D | HOH605 |
| site_id | AD2 |
| Number of Residues | 28 |
| Details | binding site for residue UGA D 402 |
| Chain | Residue |
| D | PRO85 |
| D | ARG88 |
| D | THR126 |
| D | SER127 |
| D | SER128 |
| D | TYR149 |
| D | TYR176 |
| D | PHE177 |
| D | THR178 |
| D | ARG185 |
| D | MET188 |
| D | ALA189 |
| D | ARG192 |
| D | THR204 |
| D | ILE205 |
| D | PHE206 |
| D | GLN211 |
| D | ARG213 |
| D | ILE250 |
| D | GLU276 |
| D | NAD401 |
| D | UGB403 |
| D | HOH503 |
| D | HOH522 |
| D | HOH564 |
| D | HOH590 |
| D | HOH598 |
| D | HOH604 |
| site_id | AD3 |
| Number of Residues | 29 |
| Details | binding site for residue UGB D 403 |
| Chain | Residue |
| D | PRO85 |
| D | GLY86 |
| D | VAL87 |
| D | ARG88 |
| D | THR126 |
| D | SER127 |
| D | SER128 |
| D | TYR149 |
| D | TYR176 |
| D | THR178 |
| D | ARG185 |
| D | MET188 |
| D | ALA189 |
| D | ARG192 |
| D | THR204 |
| D | ILE205 |
| D | PHE206 |
| D | GLN211 |
| D | ARG213 |
| D | ILE250 |
| D | GLU276 |
| D | NAD401 |
| D | UGA402 |
| D | HOH503 |
| D | HOH522 |
| D | HOH564 |
| D | HOH598 |
| D | HOH604 |
| D | HOH665 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. AvsedllpipLspYGVTKLSGeHLChVYH |
| Chain | Residue | Details |
| A | ALA136-HIS164 | |
