Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6ZKD

Complex I during turnover, open1

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003954	molecular_function	NADH dehydrogenase activity
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0005747	cellular_component	mitochondrial respiratory chain complex I
1	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1	0010181	molecular_function	FMN binding
1	0016020	cellular_component	membrane
1	0045271	cellular_component	respiratory chain complex I
1	0046872	molecular_function	metal ion binding
1	0051287	molecular_function	NAD binding
1	0051536	molecular_function	iron-sulfur cluster binding
1	0051539	molecular_function	4 iron, 4 sulfur cluster binding
1	0055085	biological_process	transmembrane transport
1	0070469	cellular_component	respirasome
2	0003954	molecular_function	NADH dehydrogenase activity
2	0005747	cellular_component	mitochondrial respiratory chain complex I
2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
2	0016491	molecular_function	oxidoreductase activity
2	0045271	cellular_component	respiratory chain complex I
2	0046872	molecular_function	metal ion binding
2	0051536	molecular_function	iron-sulfur cluster binding
2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3	0016020	cellular_component	membrane
3	0016491	molecular_function	oxidoreductase activity
3	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
3	0042773	biological_process	ATP synthesis coupled electron transport
3	0051536	molecular_function	iron-sulfur cluster binding
4	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
4	0048038	molecular_function	quinone binding
4	0051287	molecular_function	NAD binding
5	0005747	cellular_component	mitochondrial respiratory chain complex I
5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
5	0055085	biological_process	transmembrane transport
6	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6	0048038	molecular_function	quinone binding
6	0051536	molecular_function	iron-sulfur cluster binding
6	0051539	molecular_function	4 iron, 4 sulfur cluster binding
9	0016020	cellular_component	membrane
9	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
9	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005747	cellular_component	mitochondrial respiratory chain complex I
A	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0055085	biological_process	transmembrane transport
A	0070469	cellular_component	respirasome
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005747	cellular_component	mitochondrial respiratory chain complex I
H	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0031966	cellular_component	mitochondrial membrane
H	0032981	biological_process	mitochondrial respiratory chain complex I assembly
H	0055085	biological_process	transmembrane transport
H	0070469	cellular_component	respirasome
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005747	cellular_component	mitochondrial respiratory chain complex I
J	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0016020	cellular_component	membrane
J	0032981	biological_process	mitochondrial respiratory chain complex I assembly
J	0055085	biological_process	transmembrane transport
J	0070469	cellular_component	respirasome
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005747	cellular_component	mitochondrial respiratory chain complex I
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0016020	cellular_component	membrane
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0042773	biological_process	ATP synthesis coupled electron transport
K	0055085	biological_process	transmembrane transport
K	0070469	cellular_component	respirasome
L	0003954	molecular_function	NADH dehydrogenase activity
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005747	cellular_component	mitochondrial respiratory chain complex I
L	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0015990	biological_process	electron transport coupled proton transport
L	0016020	cellular_component	membrane
L	0032981	biological_process	mitochondrial respiratory chain complex I assembly
L	0042773	biological_process	ATP synthesis coupled electron transport
L	0055085	biological_process	transmembrane transport
L	0070469	cellular_component	respirasome
M	0003954	molecular_function	NADH dehydrogenase activity
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005747	cellular_component	mitochondrial respiratory chain complex I
M	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0015990	biological_process	electron transport coupled proton transport
M	0016020	cellular_component	membrane
M	0032981	biological_process	mitochondrial respiratory chain complex I assembly
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0045271	cellular_component	respiratory chain complex I
M	0048039	molecular_function	ubiquinone binding
M	0055085	biological_process	transmembrane transport
M	0070469	cellular_component	respirasome
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005747	cellular_component	mitochondrial respiratory chain complex I
N	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0016020	cellular_component	membrane
N	0032981	biological_process	mitochondrial respiratory chain complex I assembly
N	0055085	biological_process	transmembrane transport
N	0070469	cellular_component	respirasome
N	0072593	biological_process	reactive oxygen species metabolic process
V	0032981	biological_process	mitochondrial respiratory chain complex I assembly
X	0000035	molecular_function	acyl binding
X	0000036	molecular_function	acyl carrier activity
X	0005739	cellular_component	mitochondrion
X	0005747	cellular_component	mitochondrial respiratory chain complex I
X	0006629	biological_process	lipid metabolic process
X	0006631	biological_process	fatty acid metabolic process
X	0006633	biological_process	fatty acid biosynthetic process
Y	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
a	0005739	cellular_component	mitochondrion
a	0005747	cellular_component	mitochondrial respiratory chain complex I
b	0005747	cellular_component	mitochondrial respiratory chain complex I
b	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0005747	cellular_component	mitochondrial respiratory chain complex I
c	0016020	cellular_component	membrane
c	0022900	biological_process	electron transport chain
c	0070469	cellular_component	respirasome
f	0022904	biological_process	respiratory electron transport chain
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0005747	cellular_component	mitochondrial respiratory chain complex I
g	0006979	biological_process	response to oxidative stress
g	0016020	cellular_component	membrane
g	0031966	cellular_component	mitochondrial membrane
g	0032981	biological_process	mitochondrial respiratory chain complex I assembly
g	0070469	cellular_component	respirasome
h	0005743	cellular_component	mitochondrial inner membrane
h	0005747	cellular_component	mitochondrial respiratory chain complex I
h	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
h	0016020	cellular_component	membrane
h	0042773	biological_process	ATP synthesis coupled electron transport
i	0016020	cellular_component	membrane
i	0032981	biological_process	mitochondrial respiratory chain complex I assembly
j	0000035	molecular_function	acyl binding
j	0000036	molecular_function	acyl carrier activity
j	0005739	cellular_component	mitochondrion
j	0005747	cellular_component	mitochondrial respiratory chain complex I
j	0006629	biological_process	lipid metabolic process
j	0006631	biological_process	fatty acid metabolic process
j	0006633	biological_process	fatty acid biosynthetic process
k	0005747	cellular_component	mitochondrial respiratory chain complex I
k	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
m	0005743	cellular_component	mitochondrial inner membrane
m	0005747	cellular_component	mitochondrial respiratory chain complex I
n	0005739	cellular_component	mitochondrion
n	0022900	biological_process	electron transport chain
o	0005737	cellular_component	cytoplasm
o	0005739	cellular_component	mitochondrion
o	0005743	cellular_component	mitochondrial inner membrane
o	0005747	cellular_component	mitochondrial respiratory chain complex I
o	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
o	0016020	cellular_component	membrane
o	0032981	biological_process	mitochondrial respiratory chain complex I assembly
o	0070469	cellular_component	respirasome
p	0005739	cellular_component	mitochondrion
p	0005743	cellular_component	mitochondrial inner membrane
p	0005747	cellular_component	mitochondrial respiratory chain complex I
p	0016020	cellular_component	membrane
r	0005743	cellular_component	mitochondrial inner membrane
r	0005747	cellular_component	mitochondrial respiratory chain complex I
r	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
r	0016020	cellular_component	membrane
r	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
s	0005739	cellular_component	mitochondrion
t	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
u	0005743	cellular_component	mitochondrial inner membrane
u	0005747	cellular_component	mitochondrial respiratory chain complex I
v	0005739	cellular_component	mitochondrion
v	0005743	cellular_component	mitochondrial inner membrane
v	0005747	cellular_component	mitochondrial respiratory chain complex I
v	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
v	0016020	cellular_component	membrane
v	0032981	biological_process	mitochondrial respiratory chain complex I assembly
v	0070469	cellular_component	respirasome
x	0005739	cellular_component	mitochondrion
x	0005747	cellular_component	mitochondrial respiratory chain complex I
y	0005739	cellular_component	mitochondrion

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue SF4 1 501

Chain	Residue
1	ILE185
1	ILE404
1	CYS405
1	LEU407
1	PRO203
1	SER358
1	CYS359
1	GLY360
1	GLN361
1	CYS362
1	CYS365
1	THR403

site_id	AC2
Number of Residues	16
Details	binding site for residue FMN 1 502

Chain	Residue
1	GLY67
1	ARG68
1	GLY69
1	LYS78
1	ASN96
1	GLU99
1	GLY100
1	GLY187
1	GLU188
1	GLU189
1	VAL222
1	ALA223
1	ASN224
1	THR227
1	ALA406
1	NAI503

site_id	AC3
Number of Residues	14
Details	binding site for residue NAI 1 503

Chain	Residue
1	GLY69
1	GLY70
1	ALA71
1	PHE73
1	LYS78
1	PHE81
1	GLU101
1	TYR184
1	GLU189
1	LYS206
1	PHE209
1	SER303
1	THR331
1	FMN502

site_id	AC4
Number of Residues	9
Details	binding site for residue FES 2 300

Chain	Residue
2	CYS103
2	THR105
2	PRO107
2	CYS108
2	CYS144
2	LEU145
2	GLY146
2	ALA147
2	CYS148

site_id	AC5
Number of Residues	10
Details	binding site for residue SF4 3 801

Chain	Residue
3	HIS101
3	ASP104
3	CYS105
3	CYS108
3	GLY111
3	CYS114
3	LEU116
3	GLN117
3	VAL205
3	GLY206

site_id	AC6
Number of Residues	10
Details	binding site for residue SF4 3 802

Chain	Residue
3	MET150
3	CYS153
3	ILE154
3	CYS156
3	THR157
3	CYS159
3	VAL183
3	CYS203
3	VAL205
3	ALA207

site_id	AC7
Number of Residues	8
Details	binding site for residue FES 3 803

Chain	Residue
3	ARG39
3	CYS41
3	TYR42
3	GLY50
3	CYS52
3	ARG53
3	CYS55
3	CYS69

site_id	AC8
Number of Residues	5
Details	binding site for residue K 3 804

Chain	Residue
3	GLN110
3	ILE200
3	CYS203
3	VAL205
3	LEU208

site_id	AC9
Number of Residues	15
Details	binding site for residue 3PE 4 501

Chain	Residue
4	GLN13
4	TYR14
4	TYR20
L	PRO563
L	SER567
L	GLN570
L	MET571
M	ASN144
M	LEU147
M	PHE151
M	TYR152
M	PC1502
N	ILE284
N	TYR291
N	ARG295

site_id	AD1
Number of Residues	11
Details	binding site for residue SF4 6 300

Chain	Residue
4	2MR85
4	HIS190
6	ALA53
6	CYS54
6	CYS55
6	GLY90
6	GLY117
6	SER118
6	CYS119
6	CYS149
6	PRO150

site_id	AD2
Number of Residues	18
Details	binding site for residue PC1 9 401

Chain	Residue
4	ARG233
9	THR24
9	TRP27
9	LEU30
H	TRP179
H	PRO180
H	ALA182
H	PHE186
H	ILE187
H	TYR277
H	PHE280
H	HIS287
H	LEU288
H	ASN292
H	PHE293
H	LEU296
m	LYS14
m	GLU15

site_id	AD3
Number of Residues	11
Details	binding site for residue SF4 9 402

Chain	Residue
9	HIS65
9	CYS87
9	PRO88
9	ILE92
9	CYS116
9	ILE117
9	TYR118
9	CYS119
9	GLY120
9	CYS122
9	GLU133

site_id	AD4
Number of Residues	10
Details	binding site for residue SF4 9 403

Chain	Residue
9	CYS77
9	ILE78
9	ALA79
9	CYS80
9	LYS81
9	CYS83
9	TYR109
9	CYS126
9	VAL128
9	ILE131

site_id	AD5
Number of Residues	10
Details	binding site for residue PC1 A 401

Chain	Residue
6	ILE37
6	LEU173
6	TRP176
6	ARG179
A	LEU27
A	ASN28
A	VAL29
A	TYR30
H	PHE56
d	ASP55

site_id	AD6
Number of Residues	5
Details	binding site for residue PC1 A 402

Chain	Residue
A	ASN83
A	THR86
J	SER148
J	TYR149
J	TRP152

site_id	AD7
Number of Residues	9
Details	binding site for residue 3PE A 403

Chain	Residue
A	PHE96
A	ALA99
A	TRP106
H	LYS291
H	PRO295
m	GLU15
m	LEU18
m	VAL19
m	PHE22

site_id	AD8
Number of Residues	7
Details	binding site for residue DCQ H 501

Chain	Residue
6	TRP46
H	THR21
H	ASP51
H	ALA52
H	LEU55
H	PHE220
H	PHE224

site_id	AD9
Number of Residues	15
Details	binding site for residue 3PE H 502

Chain	Residue
A	LEU3
A	LEU7
H	MET98
H	ASN99
H	PHE104
J	ILE34
J	GLY38
J	LEU45
J	ASN46
J	SER50
J	PHE57
q	PHE139
q	ILE140
q	TRP141
z	ALA39

site_id	AE1
Number of Residues	10
Details	binding site for residue 3PE K 101

Chain	Residue
J	SER21
J	LYS23
J	VAL88
J	THR92
K	THR17
K	MET21
K	TYR22
K	ARG23
L	LYS585
V	3PE201

site_id	AE2
Number of Residues	12
Details	binding site for residue 3PE L 1001

Chain	Residue
L	THR166
L	GLN170
L	LEU173
L	TYR174
L	LEU229
L	HIS534
L	THR537
L	PRO538
L	ASN541
v	ASN87
v	ARG88
v	VAL89

site_id	AE3
Number of Residues	14
Details	binding site for residue PC1 L 1002

Chain	Residue
L	TRP66
L	HIS67
L	TRP68
L	SER77
L	ASN136
L	ILE142
L	CDL1003
W	CDL201
r	ILE80
r	TYR84
r	HIS88
r	LYS92
w	GLU87
w	PC1801

site_id	AE4
Number of Residues	22
Details	binding site for residue CDL L 1003

Chain	Residue
L	ASN23
L	PHE24
L	GLN116
L	LYS119
L	TYR120
L	ILE142
L	MET150
L	PC11002
M	PRO353
M	LEU354
M	ALA357
M	TRP358
M	LEU360
M	LEU361
M	LEU364
M	PRO370
M	PRO371
M	SER372
M	LEU445
W	LEU22
W	CDL201
w	PC1801

site_id	AE5
Number of Residues	4
Details	binding site for residue 3PE L 1004

Chain	Residue
L	MET383
L	PHE498
L	LEU502
n	VAL63

site_id	AE6
Number of Residues	9
Details	binding site for residue 3PE M 501

Chain	Residue
M	ASN188
M	TRP190
M	PHE194
M	GLY211
M	MET257
M	PRO260
M	PHE261
V	LEU87
V	CDL204

site_id	AE7
Number of Residues	13
Details	binding site for residue PC1 M 502

Chain	Residue
4	3PE501
M	ALA155
M	TYR166
M	SER191
M	PHE194
M	MET195
M	LEU197
M	VAL205
N	ILE276
N	ILE277
N	THR280
V	GLU130
V	TRP132

site_id	AE8
Number of Residues	7
Details	binding site for residue 3PE N 401

Chain	Residue
N	LYS46
N	SER125
N	ILE129
N	THR132
N	MET220
N	ARG322
N	MET329

site_id	AE9
Number of Residues	5
Details	binding site for residue 3PE N 402

Chain	Residue
N	TYR143
N	ILE345
o	LEU11
o	PHE13
o	ARG78

site_id	AF1
Number of Residues	7
Details	binding site for residue 3PE V 201

Chain	Residue
K	3PE101
L	LEU589
V	PRO45
V	SER47
V	PHE48
V	GLY51
V	VAL52

site_id	AF2
Number of Residues	4
Details	binding site for residue 3PE V 202

Chain	Residue
V	TRP9
V	LEU123
V	TRP132
V	CDL203

site_id	AF3
Number of Residues	15
Details	binding site for residue CDL V 203

Chain	Residue
L	THR576
L	SER598
L	PHE604
N	PHE113
N	LEU157
V	TYR8
V	SER31
V	VAL35
V	TYR38
V	SER39
V	LYS43
V	TYR58
V	PHE69
V	3PE202
V	CDL204

site_id	AF4
Number of Residues	12
Details	binding site for residue CDL V 204

Chain	Residue
L	THR560
L	THR565
L	ALA569
L	LYS572
M	3PE501
V	GLY108
V	ILE109
V	ALA112
V	ALA115
V	TYR116
V	THR120
V	CDL203

site_id	AF5
Number of Residues	18
Details	binding site for residue CDL W 201

Chain	Residue
L	LEU12
L	ASN65
L	PC11002
L	CDL1003
W	GLY33
W	ILE40
W	THR41
W	ASN44
W	GLU49
W	HIS69
Z	ARG48
Z	ILE51
r	TRP79
r	TYR83
r	HIS88
w	ALA78
w	TYR79
w	PC1801

site_id	AF6
Number of Residues	10
Details	binding site for residue ZMP X 101

Chain	Residue
X	ASP43
X	SER44
t	HIS11
t	GLN12
t	ARG46
t	PHE47
t	HIS50
t	LYS51
t	LEU62
t	ALA66

site_id	AF7
Number of Residues	22
Details	binding site for residue CDL Y 201

Chain	Residue
M	LEU2
M	ILE5
M	MET9
M	SER53
M	THR55
M	PHE56
M	LEU104
M	PHE105
M	PHE117
M	MET121
N	PRO256
N	PRO338
Y	PHE168
Y	TRP169
Y	THR170
Y	MET171
o	PRO29
o	ARG30
o	TYR33
o	PHE36
y	ASN30
y	LYS33

site_id	AF8
Number of Residues	5
Details	binding site for residue ZN b 300

Chain	Residue
b	CYS59
b	GLY61
b	HIS68
b	CYS84
b	CYS87

site_id	AF9
Number of Residues	22
Details	binding site for residue NDP d 401

Chain	Residue
6	ARG179
d	GLY25
d	THR27
d	GLY28
d	PHE29
d	LEU30
d	ARG50
d	CYS51
d	TRP73
d	LEU94
d	VAL95
d	GLY96
d	ARG97
d	PHE104
d	ILE132
d	SER133
d	HIS134
d	TYR145
d	LYS149
d	PRO168
d	ILE171
d	ARG177

site_id	AG1
Number of Residues	13
Details	binding site for residue ZMP g 201

Chain	Residue
g	LYS28
g	VAL31
g	TRP38
g	VAL62
g	PHE66
g	ASN69
g	ALA70
g	VAL72
g	VAL78
g	PHE105
j	ASP43
j	SER44
j	LEU45

site_id	AG2
Number of Residues	9
Details	binding site for residue 3PE i 501

Chain	Residue
6	TYR28
6	ASP35
6	TRP39
6	ARG42
6	LYS168
H	ILE49
i	ARG29
i	TRP75
i	3PE502

site_id	AG3
Number of Residues	4
Details	binding site for residue 3PE i 502

Chain	Residue
H	PHE19
i	PHE74
i	TRP75
i	3PE501

site_id	AG4
Number of Residues	11
Details	binding site for residue AMP k 501

Chain	Residue
k	ILE31
k	SEP36
k	GLU53
k	PHE82
k	TYR83
k	GLN97
k	LEU100
k	ARG104
k	ARG126
k	PHE134
k	TYR198

site_id	AG5
Number of Residues	12
Details	binding site for residue CDL o 201

Chain	Residue
N	MET323
N	THR324
N	LEU325
o	ASP45
o	ARG60
o	LEU63
o	TYR64
o	SER67
o	PHE68
x	LYS16
x	THR20
x	THR23

site_id	AG6
Number of Residues	24
Details	binding site for residue CDL o 202

Chain	Residue
M	TRP16
M	ALA90
M	ARG91
M	LEU94
M	MET98
M	LEU101
M	VAL127
M	ARG135
N	PRO238
N	THR241
N	ILE242
N	LEU257
N	MET335
k	LYS303
k	TYR304
o	GLY35
o	PHE36
o	TYR39
o	CYS40
o	LEU43
o	ILE44
o	ALA47
o	VAL53
o	LEU54

site_id	AG7
Number of Residues	8
Details	binding site for residue 3PE p 201

Chain	Residue
L	TRP557
V	TYR107
V	GLY108
p	PRO81
p	ASN82
p	THR83
p	SER86
p	GLY89

site_id	AG8
Number of Residues	5
Details	binding site for residue MYR s 201

Chain	Residue
L	TYR485
L	THR489
s	GLY1
s	ALA2
v	THR124

site_id	AG9
Number of Residues	12
Details	binding site for residue PC1 w 801

Chain	Residue
L	TRP66
L	PC11002
L	CDL1003
M	PRO64
M	TRP71
M	LEU446
W	CDL201
w	GLY73
w	SER74
w	VAL77
w	ALA78
w	TYR79

site_id	AH1
Number of Residues	15
Details	binding site for residue CDL z 101

Chain	Residue
H	TYR43
h	SER2
h	ALA3
h	THR4
h	ILE7
i	LEU3
i	VAL6
i	LEU7
i	ARG9
i	GLN13
z	MET1
z	TRP2
z	PHE3
z	LEU6
z	PRO7

Functional Information from PROSITE/UniProt

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL

Chain	Residue	Details
5	GLU131-LEU152

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE

Chain	Residue	Details
H	GLY44-GLU59

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
H	PRO197-GLY210

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
6	GLY135-PRO151

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
3	PRO38-CYS55

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
3	CYS105-GLN117

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
3	ARG152-PHE162

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
4	LEU83-LYS94

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
j	ASP39-MET54

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
j	ASP64-ILE76

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
9	CYS77-PRO88
9	CYS116-PRO127

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
1	GLY180-SER195

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
1	GLU357-GLY368

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
2	ASP134-PRO152

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	220
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
N	PRO3-SER23
N	ASP274-MET294
N	LEU325-ILE345
L	MET366-LEU386
L	LEU413-GLY433
L	LEU457-ILE477
L	TYR485-SER505
L	GLY582-LEU602
N	HIS25-MET45
N	SER67-MET87
N	MET96-PRO116
N	ILE122-LEU142
N	ILE145-GLY165
N	ILE178-PRO198
N	MET200-MET220
N	ALA237-LEU257

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)