6ZKD
Complex I during turnover, open1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| 1 | 0005739 | cellular_component | mitochondrion |
| 1 | 0005743 | cellular_component | mitochondrial inner membrane |
| 1 | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| 1 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| 1 | 0010181 | molecular_function | FMN binding |
| 1 | 0046872 | molecular_function | metal ion binding |
| 1 | 0051287 | molecular_function | NAD binding |
| 1 | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| 1 | 1902600 | biological_process | proton transmembrane transport |
| 2 | 0003954 | molecular_function | NADH dehydrogenase activity |
| 2 | 0005739 | cellular_component | mitochondrion |
| 2 | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| 2 | 0016491 | molecular_function | oxidoreductase activity |
| 2 | 0046872 | molecular_function | metal ion binding |
| 2 | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| 3 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| 3 | 0016020 | cellular_component | membrane |
| 3 | 0016491 | molecular_function | oxidoreductase activity |
| 3 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| 3 | 0042773 | biological_process | ATP synthesis coupled electron transport |
| 3 | 0051536 | molecular_function | iron-sulfur cluster binding |
| 4 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| 4 | 0048038 | molecular_function | quinone binding |
| 4 | 0051287 | molecular_function | NAD binding |
| 5 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| 5 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| 5 | 1902600 | biological_process | proton transmembrane transport |
| 6 | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| 6 | 0048038 | molecular_function | quinone binding |
| 6 | 0051536 | molecular_function | iron-sulfur cluster binding |
| 6 | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| 9 | 0016020 | cellular_component | membrane |
| 9 | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| 9 | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| A | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| A | 0030964 | cellular_component | NADH dehydrogenase complex |
| A | 0045271 | cellular_component | respiratory chain complex I |
| A | 1902600 | biological_process | proton transmembrane transport |
| H | 0003954 | molecular_function | NADH dehydrogenase activity |
| H | 0005739 | cellular_component | mitochondrion |
| H | 0005743 | cellular_component | mitochondrial inner membrane |
| H | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| H | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| H | 0009060 | biological_process | aerobic respiration |
| H | 0016020 | cellular_component | membrane |
| H | 0031966 | cellular_component | mitochondrial membrane |
| H | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| H | 0045271 | cellular_component | respiratory chain complex I |
| H | 1902600 | biological_process | proton transmembrane transport |
| J | 0005739 | cellular_component | mitochondrion |
| J | 0005743 | cellular_component | mitochondrial inner membrane |
| J | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| J | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| J | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| J | 0045271 | cellular_component | respiratory chain complex I |
| J | 1902600 | biological_process | proton transmembrane transport |
| K | 0005739 | cellular_component | mitochondrion |
| K | 0005743 | cellular_component | mitochondrial inner membrane |
| K | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| K | 0016651 | molecular_function | oxidoreductase activity, acting on NAD(P)H |
| K | 0030964 | cellular_component | NADH dehydrogenase complex |
| K | 0042773 | biological_process | ATP synthesis coupled electron transport |
| K | 0045271 | cellular_component | respiratory chain complex I |
| K | 1902600 | biological_process | proton transmembrane transport |
| L | 0003954 | molecular_function | NADH dehydrogenase activity |
| L | 0005739 | cellular_component | mitochondrion |
| L | 0005743 | cellular_component | mitochondrial inner membrane |
| L | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| L | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| L | 0015990 | biological_process | electron transport coupled proton transport |
| L | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| L | 0042773 | biological_process | ATP synthesis coupled electron transport |
| L | 0045271 | cellular_component | respiratory chain complex I |
| M | 0003954 | molecular_function | NADH dehydrogenase activity |
| M | 0005739 | cellular_component | mitochondrion |
| M | 0005743 | cellular_component | mitochondrial inner membrane |
| M | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| M | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| M | 0009060 | biological_process | aerobic respiration |
| M | 0015990 | biological_process | electron transport coupled proton transport |
| M | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| M | 0042773 | biological_process | ATP synthesis coupled electron transport |
| M | 0045271 | cellular_component | respiratory chain complex I |
| M | 0048039 | molecular_function | ubiquinone binding |
| N | 0005739 | cellular_component | mitochondrion |
| N | 0005743 | cellular_component | mitochondrial inner membrane |
| N | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| N | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| N | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| N | 0045271 | cellular_component | respiratory chain complex I |
| N | 0072593 | biological_process | reactive oxygen species metabolic process |
| N | 1902600 | biological_process | proton transmembrane transport |
| V | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| X | 0000035 | molecular_function | acyl binding |
| X | 0000036 | molecular_function | acyl carrier activity |
| X | 0005739 | cellular_component | mitochondrion |
| X | 0006633 | biological_process | fatty acid biosynthetic process |
| Y | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| a | 0005739 | cellular_component | mitochondrion |
| a | 0045271 | cellular_component | respiratory chain complex I |
| b | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| c | 0005739 | cellular_component | mitochondrion |
| c | 0005743 | cellular_component | mitochondrial inner membrane |
| c | 0022900 | biological_process | electron transport chain |
| f | 0022904 | biological_process | respiratory electron transport chain |
| g | 0005739 | cellular_component | mitochondrion |
| g | 0005743 | cellular_component | mitochondrial inner membrane |
| g | 0006979 | biological_process | response to oxidative stress |
| g | 0031966 | cellular_component | mitochondrial membrane |
| g | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| g | 0045271 | cellular_component | respiratory chain complex I |
| h | 0005739 | cellular_component | mitochondrion |
| h | 0005743 | cellular_component | mitochondrial inner membrane |
| h | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| h | 0042773 | biological_process | ATP synthesis coupled electron transport |
| i | 0016020 | cellular_component | membrane |
| i | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| j | 0000035 | molecular_function | acyl binding |
| j | 0000036 | molecular_function | acyl carrier activity |
| j | 0005739 | cellular_component | mitochondrion |
| j | 0006633 | biological_process | fatty acid biosynthetic process |
| k | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| m | 0005743 | cellular_component | mitochondrial inner membrane |
| m | 0045271 | cellular_component | respiratory chain complex I |
| n | 0005739 | cellular_component | mitochondrion |
| n | 0022900 | biological_process | electron transport chain |
| o | 0005737 | cellular_component | cytoplasm |
| o | 0005739 | cellular_component | mitochondrion |
| o | 0005743 | cellular_component | mitochondrial inner membrane |
| o | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| o | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| o | 0045271 | cellular_component | respiratory chain complex I |
| p | 0005739 | cellular_component | mitochondrion |
| p | 0005743 | cellular_component | mitochondrial inner membrane |
| r | 0005739 | cellular_component | mitochondrion |
| r | 0005743 | cellular_component | mitochondrial inner membrane |
| r | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| r | 0042775 | biological_process | mitochondrial ATP synthesis coupled electron transport |
| s | 0005739 | cellular_component | mitochondrion |
| t | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| u | 0005743 | cellular_component | mitochondrial inner membrane |
| u | 0045271 | cellular_component | respiratory chain complex I |
| v | 0005739 | cellular_component | mitochondrion |
| v | 0005743 | cellular_component | mitochondrial inner membrane |
| v | 0006120 | biological_process | mitochondrial electron transport, NADH to ubiquinone |
| v | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| x | 0005739 | cellular_component | mitochondrion |
| x | 0045271 | cellular_component | respiratory chain complex I |
| y | 0005739 | cellular_component | mitochondrion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue SF4 1 501 |
| Chain | Residue |
| 1 | ILE185 |
| 1 | ILE404 |
| 1 | CYS405 |
| 1 | LEU407 |
| 1 | PRO203 |
| 1 | SER358 |
| 1 | CYS359 |
| 1 | GLY360 |
| 1 | GLN361 |
| 1 | CYS362 |
| 1 | CYS365 |
| 1 | THR403 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue FMN 1 502 |
| Chain | Residue |
| 1 | GLY67 |
| 1 | ARG68 |
| 1 | GLY69 |
| 1 | LYS78 |
| 1 | ASN96 |
| 1 | GLU99 |
| 1 | GLY100 |
| 1 | GLY187 |
| 1 | GLU188 |
| 1 | GLU189 |
| 1 | VAL222 |
| 1 | ALA223 |
| 1 | ASN224 |
| 1 | THR227 |
| 1 | ALA406 |
| 1 | NAI503 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue NAI 1 503 |
| Chain | Residue |
| 1 | GLY69 |
| 1 | GLY70 |
| 1 | ALA71 |
| 1 | PHE73 |
| 1 | LYS78 |
| 1 | PHE81 |
| 1 | GLU101 |
| 1 | TYR184 |
| 1 | GLU189 |
| 1 | LYS206 |
| 1 | PHE209 |
| 1 | SER303 |
| 1 | THR331 |
| 1 | FMN502 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue FES 2 300 |
| Chain | Residue |
| 2 | CYS103 |
| 2 | THR105 |
| 2 | PRO107 |
| 2 | CYS108 |
| 2 | CYS144 |
| 2 | LEU145 |
| 2 | GLY146 |
| 2 | ALA147 |
| 2 | CYS148 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 3 801 |
| Chain | Residue |
| 3 | HIS101 |
| 3 | ASP104 |
| 3 | CYS105 |
| 3 | CYS108 |
| 3 | GLY111 |
| 3 | CYS114 |
| 3 | LEU116 |
| 3 | GLN117 |
| 3 | VAL205 |
| 3 | GLY206 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 3 802 |
| Chain | Residue |
| 3 | MET150 |
| 3 | CYS153 |
| 3 | ILE154 |
| 3 | CYS156 |
| 3 | THR157 |
| 3 | CYS159 |
| 3 | VAL183 |
| 3 | CYS203 |
| 3 | VAL205 |
| 3 | ALA207 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue FES 3 803 |
| Chain | Residue |
| 3 | ARG39 |
| 3 | CYS41 |
| 3 | TYR42 |
| 3 | GLY50 |
| 3 | CYS52 |
| 3 | ARG53 |
| 3 | CYS55 |
| 3 | CYS69 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue K 3 804 |
| Chain | Residue |
| 3 | GLN110 |
| 3 | ILE200 |
| 3 | CYS203 |
| 3 | VAL205 |
| 3 | LEU208 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | binding site for residue 3PE 4 501 |
| Chain | Residue |
| 4 | GLN13 |
| 4 | TYR14 |
| 4 | TYR20 |
| L | PRO563 |
| L | SER567 |
| L | GLN570 |
| L | MET571 |
| M | ASN144 |
| M | LEU147 |
| M | PHE151 |
| M | TYR152 |
| M | PC1502 |
| N | ILE284 |
| N | TYR291 |
| N | ARG295 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 6 300 |
| Chain | Residue |
| 4 | 2MR85 |
| 4 | HIS190 |
| 6 | ALA53 |
| 6 | CYS54 |
| 6 | CYS55 |
| 6 | GLY90 |
| 6 | GLY117 |
| 6 | SER118 |
| 6 | CYS119 |
| 6 | CYS149 |
| 6 | PRO150 |
| site_id | AD2 |
| Number of Residues | 18 |
| Details | binding site for residue PC1 9 401 |
| Chain | Residue |
| 4 | ARG233 |
| 9 | THR24 |
| 9 | TRP27 |
| 9 | LEU30 |
| H | TRP179 |
| H | PRO180 |
| H | ALA182 |
| H | PHE186 |
| H | ILE187 |
| H | TYR277 |
| H | PHE280 |
| H | HIS287 |
| H | LEU288 |
| H | ASN292 |
| H | PHE293 |
| H | LEU296 |
| m | LYS14 |
| m | GLU15 |
| site_id | AD3 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 9 402 |
| Chain | Residue |
| 9 | HIS65 |
| 9 | CYS87 |
| 9 | PRO88 |
| 9 | ILE92 |
| 9 | CYS116 |
| 9 | ILE117 |
| 9 | TYR118 |
| 9 | CYS119 |
| 9 | GLY120 |
| 9 | CYS122 |
| 9 | GLU133 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 9 403 |
| Chain | Residue |
| 9 | CYS77 |
| 9 | ILE78 |
| 9 | ALA79 |
| 9 | CYS80 |
| 9 | LYS81 |
| 9 | CYS83 |
| 9 | TYR109 |
| 9 | CYS126 |
| 9 | VAL128 |
| 9 | ILE131 |
| site_id | AD5 |
| Number of Residues | 10 |
| Details | binding site for residue PC1 A 401 |
| Chain | Residue |
| 6 | ILE37 |
| 6 | LEU173 |
| 6 | TRP176 |
| 6 | ARG179 |
| A | LEU27 |
| A | ASN28 |
| A | VAL29 |
| A | TYR30 |
| H | PHE56 |
| d | ASP55 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue PC1 A 402 |
| Chain | Residue |
| A | ASN83 |
| A | THR86 |
| J | SER148 |
| J | TYR149 |
| J | TRP152 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue 3PE A 403 |
| Chain | Residue |
| A | PHE96 |
| A | ALA99 |
| A | TRP106 |
| H | LYS291 |
| H | PRO295 |
| m | GLU15 |
| m | LEU18 |
| m | VAL19 |
| m | PHE22 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue DCQ H 501 |
| Chain | Residue |
| 6 | TRP46 |
| H | THR21 |
| H | ASP51 |
| H | ALA52 |
| H | LEU55 |
| H | PHE220 |
| H | PHE224 |
| site_id | AD9 |
| Number of Residues | 15 |
| Details | binding site for residue 3PE H 502 |
| Chain | Residue |
| A | LEU3 |
| A | LEU7 |
| H | MET98 |
| H | ASN99 |
| H | PHE104 |
| J | ILE34 |
| J | GLY38 |
| J | LEU45 |
| J | ASN46 |
| J | SER50 |
| J | PHE57 |
| q | PHE139 |
| q | ILE140 |
| q | TRP141 |
| z | ALA39 |
| site_id | AE1 |
| Number of Residues | 10 |
| Details | binding site for residue 3PE K 101 |
| Chain | Residue |
| J | SER21 |
| J | LYS23 |
| J | VAL88 |
| J | THR92 |
| K | THR17 |
| K | MET21 |
| K | TYR22 |
| K | ARG23 |
| L | LYS585 |
| V | 3PE201 |
| site_id | AE2 |
| Number of Residues | 12 |
| Details | binding site for residue 3PE L 1001 |
| Chain | Residue |
| L | THR166 |
| L | GLN170 |
| L | LEU173 |
| L | TYR174 |
| L | LEU229 |
| L | HIS534 |
| L | THR537 |
| L | PRO538 |
| L | ASN541 |
| v | ASN87 |
| v | ARG88 |
| v | VAL89 |
| site_id | AE3 |
| Number of Residues | 14 |
| Details | binding site for residue PC1 L 1002 |
| Chain | Residue |
| L | TRP66 |
| L | HIS67 |
| L | TRP68 |
| L | SER77 |
| L | ASN136 |
| L | ILE142 |
| L | CDL1003 |
| W | CDL201 |
| r | ILE80 |
| r | TYR84 |
| r | HIS88 |
| r | LYS92 |
| w | GLU87 |
| w | PC1801 |
| site_id | AE4 |
| Number of Residues | 22 |
| Details | binding site for residue CDL L 1003 |
| Chain | Residue |
| L | ASN23 |
| L | PHE24 |
| L | GLN116 |
| L | LYS119 |
| L | TYR120 |
| L | ILE142 |
| L | MET150 |
| L | PC11002 |
| M | PRO353 |
| M | LEU354 |
| M | ALA357 |
| M | TRP358 |
| M | LEU360 |
| M | LEU361 |
| M | LEU364 |
| M | PRO370 |
| M | PRO371 |
| M | SER372 |
| M | LEU445 |
| W | LEU22 |
| W | CDL201 |
| w | PC1801 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue 3PE L 1004 |
| Chain | Residue |
| L | MET383 |
| L | PHE498 |
| L | LEU502 |
| n | VAL63 |
| site_id | AE6 |
| Number of Residues | 9 |
| Details | binding site for residue 3PE M 501 |
| Chain | Residue |
| M | ASN188 |
| M | TRP190 |
| M | PHE194 |
| M | GLY211 |
| M | MET257 |
| M | PRO260 |
| M | PHE261 |
| V | LEU87 |
| V | CDL204 |
| site_id | AE7 |
| Number of Residues | 13 |
| Details | binding site for residue PC1 M 502 |
| Chain | Residue |
| 4 | 3PE501 |
| M | ALA155 |
| M | TYR166 |
| M | SER191 |
| M | PHE194 |
| M | MET195 |
| M | LEU197 |
| M | VAL205 |
| N | ILE276 |
| N | ILE277 |
| N | THR280 |
| V | GLU130 |
| V | TRP132 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue 3PE N 401 |
| Chain | Residue |
| N | LYS46 |
| N | SER125 |
| N | ILE129 |
| N | THR132 |
| N | MET220 |
| N | ARG322 |
| N | MET329 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue 3PE N 402 |
| Chain | Residue |
| N | TYR143 |
| N | ILE345 |
| o | LEU11 |
| o | PHE13 |
| o | ARG78 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue 3PE V 201 |
| Chain | Residue |
| K | 3PE101 |
| L | LEU589 |
| V | PRO45 |
| V | SER47 |
| V | PHE48 |
| V | GLY51 |
| V | VAL52 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue 3PE V 202 |
| Chain | Residue |
| V | TRP9 |
| V | LEU123 |
| V | TRP132 |
| V | CDL203 |
| site_id | AF3 |
| Number of Residues | 15 |
| Details | binding site for residue CDL V 203 |
| Chain | Residue |
| L | THR576 |
| L | SER598 |
| L | PHE604 |
| N | PHE113 |
| N | LEU157 |
| V | TYR8 |
| V | SER31 |
| V | VAL35 |
| V | TYR38 |
| V | SER39 |
| V | LYS43 |
| V | TYR58 |
| V | PHE69 |
| V | 3PE202 |
| V | CDL204 |
| site_id | AF4 |
| Number of Residues | 12 |
| Details | binding site for residue CDL V 204 |
| Chain | Residue |
| L | THR560 |
| L | THR565 |
| L | ALA569 |
| L | LYS572 |
| M | 3PE501 |
| V | GLY108 |
| V | ILE109 |
| V | ALA112 |
| V | ALA115 |
| V | TYR116 |
| V | THR120 |
| V | CDL203 |
| site_id | AF5 |
| Number of Residues | 18 |
| Details | binding site for residue CDL W 201 |
| Chain | Residue |
| L | LEU12 |
| L | ASN65 |
| L | PC11002 |
| L | CDL1003 |
| W | GLY33 |
| W | ILE40 |
| W | THR41 |
| W | ASN44 |
| W | GLU49 |
| W | HIS69 |
| Z | ARG48 |
| Z | ILE51 |
| r | TRP79 |
| r | TYR83 |
| r | HIS88 |
| w | ALA78 |
| w | TYR79 |
| w | PC1801 |
| site_id | AF6 |
| Number of Residues | 10 |
| Details | binding site for residue ZMP X 101 |
| Chain | Residue |
| X | ASP43 |
| X | SER44 |
| t | HIS11 |
| t | GLN12 |
| t | ARG46 |
| t | PHE47 |
| t | HIS50 |
| t | LYS51 |
| t | LEU62 |
| t | ALA66 |
| site_id | AF7 |
| Number of Residues | 22 |
| Details | binding site for residue CDL Y 201 |
| Chain | Residue |
| M | LEU2 |
| M | ILE5 |
| M | MET9 |
| M | SER53 |
| M | THR55 |
| M | PHE56 |
| M | LEU104 |
| M | PHE105 |
| M | PHE117 |
| M | MET121 |
| N | PRO256 |
| N | PRO338 |
| Y | PHE168 |
| Y | TRP169 |
| Y | THR170 |
| Y | MET171 |
| o | PRO29 |
| o | ARG30 |
| o | TYR33 |
| o | PHE36 |
| y | ASN30 |
| y | LYS33 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue ZN b 300 |
| Chain | Residue |
| b | CYS59 |
| b | GLY61 |
| b | HIS68 |
| b | CYS84 |
| b | CYS87 |
| site_id | AF9 |
| Number of Residues | 22 |
| Details | binding site for residue NDP d 401 |
| Chain | Residue |
| 6 | ARG179 |
| d | GLY25 |
| d | THR27 |
| d | GLY28 |
| d | PHE29 |
| d | LEU30 |
| d | ARG50 |
| d | CYS51 |
| d | TRP73 |
| d | LEU94 |
| d | VAL95 |
| d | GLY96 |
| d | ARG97 |
| d | PHE104 |
| d | ILE132 |
| d | SER133 |
| d | HIS134 |
| d | TYR145 |
| d | LYS149 |
| d | PRO168 |
| d | ILE171 |
| d | ARG177 |
| site_id | AG1 |
| Number of Residues | 13 |
| Details | binding site for residue ZMP g 201 |
| Chain | Residue |
| g | LYS28 |
| g | VAL31 |
| g | TRP38 |
| g | VAL62 |
| g | PHE66 |
| g | ASN69 |
| g | ALA70 |
| g | VAL72 |
| g | VAL78 |
| g | PHE105 |
| j | ASP43 |
| j | SER44 |
| j | LEU45 |
| site_id | AG2 |
| Number of Residues | 9 |
| Details | binding site for residue 3PE i 501 |
| Chain | Residue |
| 6 | TYR28 |
| 6 | ASP35 |
| 6 | TRP39 |
| 6 | ARG42 |
| 6 | LYS168 |
| H | ILE49 |
| i | ARG29 |
| i | TRP75 |
| i | 3PE502 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue 3PE i 502 |
| Chain | Residue |
| H | PHE19 |
| i | PHE74 |
| i | TRP75 |
| i | 3PE501 |
| site_id | AG4 |
| Number of Residues | 11 |
| Details | binding site for residue AMP k 501 |
| Chain | Residue |
| k | ILE31 |
| k | SEP36 |
| k | GLU53 |
| k | PHE82 |
| k | TYR83 |
| k | GLN97 |
| k | LEU100 |
| k | ARG104 |
| k | ARG126 |
| k | PHE134 |
| k | TYR198 |
| site_id | AG5 |
| Number of Residues | 12 |
| Details | binding site for residue CDL o 201 |
| Chain | Residue |
| N | MET323 |
| N | THR324 |
| N | LEU325 |
| o | ASP45 |
| o | ARG60 |
| o | LEU63 |
| o | TYR64 |
| o | SER67 |
| o | PHE68 |
| x | LYS16 |
| x | THR20 |
| x | THR23 |
| site_id | AG6 |
| Number of Residues | 24 |
| Details | binding site for residue CDL o 202 |
| Chain | Residue |
| M | TRP16 |
| M | ALA90 |
| M | ARG91 |
| M | LEU94 |
| M | MET98 |
| M | LEU101 |
| M | VAL127 |
| M | ARG135 |
| N | PRO238 |
| N | THR241 |
| N | ILE242 |
| N | LEU257 |
| N | MET335 |
| k | LYS303 |
| k | TYR304 |
| o | GLY35 |
| o | PHE36 |
| o | TYR39 |
| o | CYS40 |
| o | LEU43 |
| o | ILE44 |
| o | ALA47 |
| o | VAL53 |
| o | LEU54 |
| site_id | AG7 |
| Number of Residues | 8 |
| Details | binding site for residue 3PE p 201 |
| Chain | Residue |
| L | TRP557 |
| V | TYR107 |
| V | GLY108 |
| p | PRO81 |
| p | ASN82 |
| p | THR83 |
| p | SER86 |
| p | GLY89 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue MYR s 201 |
| Chain | Residue |
| L | TYR485 |
| L | THR489 |
| s | GLY1 |
| s | ALA2 |
| v | THR124 |
| site_id | AG9 |
| Number of Residues | 12 |
| Details | binding site for residue PC1 w 801 |
| Chain | Residue |
| L | TRP66 |
| L | PC11002 |
| L | CDL1003 |
| M | PRO64 |
| M | TRP71 |
| M | LEU446 |
| W | CDL201 |
| w | GLY73 |
| w | SER74 |
| w | VAL77 |
| w | ALA78 |
| w | TYR79 |
| site_id | AH1 |
| Number of Residues | 15 |
| Details | binding site for residue CDL z 101 |
| Chain | Residue |
| H | TYR43 |
| h | SER2 |
| h | ALA3 |
| h | THR4 |
| h | ILE7 |
| i | LEU3 |
| i | VAL6 |
| i | LEU7 |
| i | ARG9 |
| i | GLN13 |
| z | MET1 |
| z | TRP2 |
| z | PHE3 |
| z | LEU6 |
| z | PRO7 |
Functional Information from PROSITE/UniProt
| site_id | PS00012 |
| Number of Residues | 16 |
| Details | PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM |
| Chain | Residue | Details |
| j | ASP39-MET54 |
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI |
| Chain | Residue | Details |
| j | ASP64-ILE76 |
| site_id | PS00198 |
| Number of Residues | 12 |
| Details | 4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP |
| Chain | Residue | Details |
| 9 | CYS77-PRO88 | |
| 9 | CYS116-PRO127 |
| site_id | PS00535 |
| Number of Residues | 12 |
| Details | COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK |
| Chain | Residue | Details |
| 4 | LEU83-LYS94 |
| site_id | PS00542 |
| Number of Residues | 22 |
| Details | COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL |
| Chain | Residue | Details |
| 5 | GLU131-LEU152 |
| site_id | PS00641 |
| Number of Residues | 18 |
| Details | COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC |
| Chain | Residue | Details |
| 3 | PRO38-CYS55 |
| site_id | PS00642 |
| Number of Residues | 13 |
| Details | COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ |
| Chain | Residue | Details |
| 3 | CYS105-GLN117 |
| site_id | PS00643 |
| Number of Residues | 11 |
| Details | COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF |
| Chain | Residue | Details |
| 3 | ARG152-PHE162 |
| site_id | PS00644 |
| Number of Residues | 16 |
| Details | COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES |
| Chain | Residue | Details |
| 1 | GLY180-SER195 |
| site_id | PS00645 |
| Number of Residues | 12 |
| Details | COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG |
| Chain | Residue | Details |
| 1 | GLU357-GLY368 |
| site_id | PS00667 |
| Number of Residues | 16 |
| Details | COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE |
| Chain | Residue | Details |
| H | GLY44-GLU59 |
| site_id | PS00668 |
| Number of Residues | 14 |
| Details | COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G |
| Chain | Residue | Details |
| H | PRO197-GLY210 |
| site_id | PS01099 |
| Number of Residues | 19 |
| Details | COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP |
| Chain | Residue | Details |
| 2 | ASP134-PRO152 |
| site_id | PS01150 |
| Number of Residues | 17 |
| Details | COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP |
| Chain | Residue | Details |
| 6 | GLY135-PRO151 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| N | PRO3-SER23 | |
| N | ASP274-MET294 | |
| N | LEU325-ILE345 | |
| L | MET366-LEU386 | |
| L | LEU413-GLY433 | |
| L | LEU457-ILE477 | |
| L | TYR485-SER505 | |
| L | GLY582-LEU602 | |
| N | HIS25-MET45 | |
| N | SER67-MET87 | |
| N | MET96-PRO116 | |
| N | ILE122-LEU142 | |
| N | ILE145-GLY165 | |
| N | ILE178-PRO198 | |
| N | MET200-MET220 | |
| N | ALA237-LEU257 |
