Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6ZIU

bovine ATP synthase stator domain, state 3

Functional Information from GO Data

Chain	GOid	namespace	contents
8	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
8	0005739	cellular_component	mitochondrion
8	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
8	0006754	biological_process	ATP biosynthetic process
8	0006811	biological_process	monoatomic ion transport
8	0015078	molecular_function	proton transmembrane transporter activity
8	0015986	biological_process	proton motive force-driven ATP synthesis
8	0016020	cellular_component	membrane
8	0031966	cellular_component	mitochondrial membrane
8	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
8	1902600	biological_process	proton transmembrane transport
C	0000166	molecular_function	nucleotide binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
C	0005754	cellular_component	mitochondrial proton-transporting ATP synthase, catalytic core
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0006811	biological_process	monoatomic ion transport
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0016020	cellular_component	membrane
C	0032559	molecular_function	adenyl ribonucleotide binding
C	0043531	molecular_function	ADP binding
C	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
C	0046034	biological_process	ATP metabolic process
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
S	0015986	biological_process	proton motive force-driven ATP synthesis
S	0016020	cellular_component	membrane
S	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
a	0006754	biological_process	ATP biosynthetic process
a	0006811	biological_process	monoatomic ion transport
a	0015078	molecular_function	proton transmembrane transporter activity
a	0015986	biological_process	proton motive force-driven ATP synthesis
a	0016020	cellular_component	membrane
a	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
a	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
a	1902600	biological_process	proton transmembrane transport
b	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
b	0015078	molecular_function	proton transmembrane transporter activity
b	0015986	biological_process	proton motive force-driven ATP synthesis
d	0000274	cellular_component	mitochondrial proton-transporting ATP synthase, stator stalk
d	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
d	0005739	cellular_component	mitochondrion
d	0005743	cellular_component	mitochondrial inner membrane
d	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
d	0006811	biological_process	monoatomic ion transport
d	0015078	molecular_function	proton transmembrane transporter activity
d	0015986	biological_process	proton motive force-driven ATP synthesis
d	0016020	cellular_component	membrane
d	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
d	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
d	1902600	biological_process	proton transmembrane transport
e	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
e	0006754	biological_process	ATP biosynthetic process
e	0006811	biological_process	monoatomic ion transport
e	0015078	molecular_function	proton transmembrane transporter activity
e	0015986	biological_process	proton motive force-driven ATP synthesis
e	0016020	cellular_component	membrane
e	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
e	1902600	biological_process	proton transmembrane transport
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
f	0006754	biological_process	ATP biosynthetic process
f	0006811	biological_process	monoatomic ion transport
f	0016020	cellular_component	membrane
f	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
f	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
f	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
f	1902600	biological_process	proton transmembrane transport
g	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
g	0006754	biological_process	ATP biosynthetic process
g	0006811	biological_process	monoatomic ion transport
g	0015078	molecular_function	proton transmembrane transporter activity
g	0015986	biological_process	proton motive force-driven ATP synthesis
g	0016020	cellular_component	membrane
g	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
g	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
g	1902600	biological_process	proton transmembrane transport
h	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
h	0015078	molecular_function	proton transmembrane transporter activity
h	0015986	biological_process	proton motive force-driven ATP synthesis
j	0005739	cellular_component	mitochondrion
j	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
j	0016020	cellular_component	membrane
j	0031966	cellular_component	mitochondrial membrane

Functional Information from PROSITE/UniProt

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. ALAVRLTANI

Chain	Residue	Details
a	ALA155-ILE164

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAINVGLSVS

Chain	Residue	Details
C	PRO363-SER372

site_id	PS00389
Number of Residues	20
Details	ATPASE_DELTA ATP synthase delta (OSCP) subunit signature. LkLevkIDpSImGGMIVRiG

Chain	Residue	Details
S	LEU148-GLY167

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:17895376, ECO:0000269\|PubMed:8065448, ECO:0000269\|PubMed:8790345, ECO:0000269\|PubMed:9687365, ECO:0007744\|PDB:1BMF, ECO:0007744\|PDB:1COW, ECO:0007744\|PDB:1E1Q, ECO:0007744\|PDB:1E1R, ECO:0007744\|PDB:1E79, ECO:0007744\|PDB:1EFR, ECO:0007744\|PDB:1H8H, ECO:0007744\|PDB:1NBM, ECO:0007744\|PDB:1OHH, ECO:0007744\|PDB:2CK3, ECO:0007744\|PDB:2JDI, ECO:0007744\|PDB:2JIZ, ECO:0007744\|PDB:2JJ1, ECO:0007744\|PDB:2JJ2, ECO:0007744\|PDB:2V7Q, ECO:0007744\|PDB:2WSS, ECO:0007744\|PDB:2XND, ECO:0007744\|PDB:4TSF, ECO:0007744\|PDB:4TT3, ECO:0007744\|PDB:4YXW, ECO:0007744\|PDB:4Z1M

Chain	Residue	Details
C	ASP170
C	GLN430
S	LYS47
S	LYS50
S	LYS153
a	ALA189-ILE209

site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Required for activity => ECO:0000250

Chain	Residue	Details
C	SER370
S	LYS176
b	LYS120
b	LYS202

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269\|PubMed:2864455

Chain	Residue	Details
C	GLU1
S	LYS135
S	LYS139
d	LYS143
d	LYS148

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P25705

Chain	Residue	Details
C	SER10
C	SER22
C	SER123
C	SER141

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine; alternate => ECO:0000250\|UniProtKB:P25705

Chain	Residue	Details
C	SER33

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:Q03265

Chain	Residue	Details
C	SER63

site_id	SWS_FT_FI7
Number of Residues	5
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:Q03265

Chain	Residue	Details
C	LYS80
C	LYS83
C	LYS89
C	LYS197
C	LYS498

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:P15999

Chain	Residue	Details
C	THR91

site_id	SWS_FT_FI9
Number of Residues	11
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250\|UniProtKB:Q03265

Chain	Residue	Details
C	LYS118
C	LYS488
C	LYS496
C	LYS124
C	LYS187
C	LYS196
C	LYS218
C	LYS262
C	LYS384
C	LYS455
C	LYS463

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine => ECO:0000250\|UniProtKB:Q03265

Chain	Residue	Details
C	ARG161

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P25705

Chain	Residue	Details
C	LYS391

site_id	SWS_FT_FI12
Number of Residues	1
Details	CARBOHYD: O-linked (GlcNAc) serine; alternate => ECO:0000250

Chain	Residue	Details
C	SER33

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	1
Details	M-CSA 178

Chain	Residue	Details
C	ARG373	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)