Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6ZGA

COPII on membranes, inner coat

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0003400	biological_process	regulation of COPII vesicle coating
A	0005096	molecular_function	GTPase activator activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0006886	biological_process	intracellular protein transport
A	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
A	0008270	molecular_function	zinc ion binding
A	0012507	cellular_component	ER to Golgi transport vesicle membrane
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
A	0016236	biological_process	macroautophagy
A	0030127	cellular_component	COPII vesicle coat
A	0031410	cellular_component	cytoplasmic vesicle
A	0046872	molecular_function	metal ion binding
A	0061709	biological_process	reticulophagy
A	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
A	0070971	cellular_component	endoplasmic reticulum exit site
A	0090110	biological_process	COPII-coated vesicle cargo loading
A	0090114	biological_process	COPII-coated vesicle budding
A	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
B	0000139	cellular_component	Golgi membrane
B	0000149	molecular_function	SNARE binding
B	0000329	cellular_component	fungal-type vacuole membrane
B	0005048	molecular_function	signal sequence binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0006886	biological_process	intracellular protein transport
B	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
B	0008270	molecular_function	zinc ion binding
B	0012507	cellular_component	ER to Golgi transport vesicle membrane
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
B	0016236	biological_process	macroautophagy
B	0030127	cellular_component	COPII vesicle coat
B	0031410	cellular_component	cytoplasmic vesicle
B	0046872	molecular_function	metal ion binding
B	0046907	biological_process	intracellular transport
B	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
B	0070971	cellular_component	endoplasmic reticulum exit site
B	0090110	biological_process	COPII-coated vesicle cargo loading
B	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
C	0000139	cellular_component	Golgi membrane
C	0000266	biological_process	mitochondrial fission
C	0003400	biological_process	regulation of COPII vesicle coating
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005739	cellular_component	mitochondrion
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005794	cellular_component	Golgi apparatus
C	0006886	biological_process	intracellular protein transport
C	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
C	0006998	biological_process	nuclear envelope organization
C	0007006	biological_process	mitochondrial membrane organization
C	0012507	cellular_component	ER to Golgi transport vesicle membrane
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0016050	biological_process	vesicle organization
C	0016192	biological_process	vesicle-mediated transport
C	0016787	molecular_function	hydrolase activity
C	0030127	cellular_component	COPII vesicle coat
C	0031410	cellular_component	cytoplasmic vesicle
C	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
C	0061024	biological_process	membrane organization
C	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
C	0070971	cellular_component	endoplasmic reticulum exit site
C	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
E	0000139	cellular_component	Golgi membrane
E	0003400	biological_process	regulation of COPII vesicle coating
E	0005096	molecular_function	GTPase activator activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005783	cellular_component	endoplasmic reticulum
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005794	cellular_component	Golgi apparatus
E	0006886	biological_process	intracellular protein transport
E	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
E	0008270	molecular_function	zinc ion binding
E	0012507	cellular_component	ER to Golgi transport vesicle membrane
E	0015031	biological_process	protein transport
E	0016020	cellular_component	membrane
E	0016192	biological_process	vesicle-mediated transport
E	0016236	biological_process	macroautophagy
E	0030127	cellular_component	COPII vesicle coat
E	0031410	cellular_component	cytoplasmic vesicle
E	0046872	molecular_function	metal ion binding
E	0061709	biological_process	reticulophagy
E	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
E	0070971	cellular_component	endoplasmic reticulum exit site
E	0090110	biological_process	COPII-coated vesicle cargo loading
E	0090114	biological_process	COPII-coated vesicle budding
E	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
F	0000139	cellular_component	Golgi membrane
F	0000149	molecular_function	SNARE binding
F	0000329	cellular_component	fungal-type vacuole membrane
F	0005048	molecular_function	signal sequence binding
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005794	cellular_component	Golgi apparatus
F	0006886	biological_process	intracellular protein transport
F	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
F	0008270	molecular_function	zinc ion binding
F	0012507	cellular_component	ER to Golgi transport vesicle membrane
F	0015031	biological_process	protein transport
F	0016020	cellular_component	membrane
F	0016192	biological_process	vesicle-mediated transport
F	0016236	biological_process	macroautophagy
F	0030127	cellular_component	COPII vesicle coat
F	0031410	cellular_component	cytoplasmic vesicle
F	0046872	molecular_function	metal ion binding
F	0046907	biological_process	intracellular transport
F	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
F	0070971	cellular_component	endoplasmic reticulum exit site
F	0090110	biological_process	COPII-coated vesicle cargo loading
F	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
G	0000139	cellular_component	Golgi membrane
G	0000266	biological_process	mitochondrial fission
G	0003400	biological_process	regulation of COPII vesicle coating
G	0003924	molecular_function	GTPase activity
G	0005515	molecular_function	protein binding
G	0005525	molecular_function	GTP binding
G	0005739	cellular_component	mitochondrion
G	0005783	cellular_component	endoplasmic reticulum
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0005794	cellular_component	Golgi apparatus
G	0006886	biological_process	intracellular protein transport
G	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
G	0006998	biological_process	nuclear envelope organization
G	0007006	biological_process	mitochondrial membrane organization
G	0012507	cellular_component	ER to Golgi transport vesicle membrane
G	0015031	biological_process	protein transport
G	0016020	cellular_component	membrane
G	0016050	biological_process	vesicle organization
G	0016192	biological_process	vesicle-mediated transport
G	0016787	molecular_function	hydrolase activity
G	0030127	cellular_component	COPII vesicle coat
G	0031410	cellular_component	cytoplasmic vesicle
G	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
G	0061024	biological_process	membrane organization
G	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
G	0070971	cellular_component	endoplasmic reticulum exit site
G	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 801

Chain	Residue
A	CYS56
A	CYS61
A	SER63
A	CYS80
A	CYS83

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 1001

Chain	Residue
B	CYS231
B	CYS234
B	CYS253
B	CYS256

site_id	AC3
Number of Residues	17
Details	binding site for residue GNP C 201

Chain	Residue
A	ARG722
C	ASP32
C	ASN33
C	ALA34
C	GLY35
C	LYS36
C	THR37
C	THR38
C	THR50
C	PRO53
C	THR54
C	GLY76
C	ASN132
C	LYS133
C	VAL173
C	VAL174
C	MG202

site_id	AC4
Number of Residues	3
Details	binding site for residue MG C 202

Chain	Residue
C	LYS36
C	THR37
C	GNP201

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN E 801

Chain	Residue
E	CYS56
E	CYS61
E	CYS80
E	CYS83

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN F 1001

Chain	Residue
F	CYS231
F	CYS234
F	CYS253
F	CYS256

site_id	AC7
Number of Residues	3
Details	binding site for residue MG G 202

Chain	Residue
G	LYS36
G	THR37
G	GNP201

site_id	AC8
Number of Residues	19
Details	binding site for Di-peptide GNP G 201 and VAL G 174

Chain	Residue
E	ARG722
G	LEU31
G	ASN33
G	ALA34
G	GLY35
G	LYS36
G	THR37
G	THR38
G	GLN52
G	PRO53
G	THR54
G	ASN132
G	LYS133
G	ASP135
G	SER172
G	VAL173
G	MET175
G	ARG176
G	MG202

site_id	AC9
Number of Residues	17
Details	binding site for Di-peptide GNP G 201 and PRO G 53

Chain	Residue
E	ARG722
E	PHE723
G	LEU31
G	ASN33
G	ALA34
G	GLY35
G	LYS36
G	THR37
G	THR38
G	GLN52
G	THR54
G	TRP55
G	ASN132
G	LYS133
G	ASP135
G	VAL174
G	MG202

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING:

Chain	Residue	Details
G	GLY30
G	ASP73
G	ASN132
B	CYS256
F	CYS231
F	CYS234
F	CYS253
F	CYS256

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:19779198

Chain	Residue	Details
G	THR155
F	SER178

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18407956, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
G	SER157

site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744\|PubMed:22106047

Chain	Residue	Details
G	LYS133

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)