6ZFB

Structure of the B. subtilis RNA POLYMERASE in complex with HelD (dimer)

Functional Information from GO Data

Chain	GOid	namespace	contents
d	0006351	biological_process	DNA-templated transcription
d	0006355	biological_process	regulation of DNA-templated transcription
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
e	0000428	cellular_component	DNA-directed RNA polymerase complex
e	0003677	molecular_function	DNA binding
e	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
e	0005737	cellular_component	cytoplasm
e	0006351	biological_process	DNA-templated transcription
e	0009295	cellular_component	nucleoid
e	0016779	molecular_function	nucleotidyltransferase activity
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0005737	cellular_component	cytoplasm
E	0006351	biological_process	DNA-templated transcription
E	0009295	cellular_component	nucleoid
E	0016779	molecular_function	nucleotidyltransferase activity
h	0000725	biological_process	recombinational repair
h	0003677	molecular_function	DNA binding
h	0003678	molecular_function	DNA helicase activity
h	0004386	molecular_function	helicase activity
h	0005524	molecular_function	ATP binding
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0016787	molecular_function	hydrolase activity
h	0016887	molecular_function	ATP hydrolysis activity
h	0032508	biological_process	DNA duplex unwinding
h	0043138	molecular_function	3'-5' DNA helicase activity
H	0000725	biological_process	recombinational repair
H	0003677	molecular_function	DNA binding
H	0003678	molecular_function	DNA helicase activity
H	0004386	molecular_function	helicase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0016787	molecular_function	hydrolase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0032508	biological_process	DNA duplex unwinding
H	0043138	molecular_function	3'-5' DNA helicase activity
u	0000428	cellular_component	DNA-directed RNA polymerase complex
u	0003677	molecular_function	DNA binding
u	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
u	0005515	molecular_function	protein binding
u	0005737	cellular_component	cytoplasm
u	0006351	biological_process	DNA-templated transcription
u	0016779	molecular_function	nucleotidyltransferase activity
u	0034062	molecular_function	5'-3' RNA polymerase activity
u	0046983	molecular_function	protein dimerization activity
U	0000428	cellular_component	DNA-directed RNA polymerase complex
U	0003677	molecular_function	DNA binding
U	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0006351	biological_process	DNA-templated transcription
U	0016779	molecular_function	nucleotidyltransferase activity
U	0034062	molecular_function	5'-3' RNA polymerase activity
U	0046983	molecular_function	protein dimerization activity
v	0000428	cellular_component	DNA-directed RNA polymerase complex
v	0003677	molecular_function	DNA binding
v	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
v	0005515	molecular_function	protein binding
v	0005737	cellular_component	cytoplasm
v	0006351	biological_process	DNA-templated transcription
v	0016779	molecular_function	nucleotidyltransferase activity
v	0034062	molecular_function	5'-3' RNA polymerase activity
v	0046983	molecular_function	protein dimerization activity
V	0000428	cellular_component	DNA-directed RNA polymerase complex
V	0003677	molecular_function	DNA binding
V	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
V	0005515	molecular_function	protein binding
V	0005737	cellular_component	cytoplasm
V	0006351	biological_process	DNA-templated transcription
V	0016779	molecular_function	nucleotidyltransferase activity
V	0034062	molecular_function	5'-3' RNA polymerase activity
V	0046983	molecular_function	protein dimerization activity
x	0000428	cellular_component	DNA-directed RNA polymerase complex
x	0003677	molecular_function	DNA binding
x	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
x	0006351	biological_process	DNA-templated transcription
x	0016779	molecular_function	nucleotidyltransferase activity
x	0032549	molecular_function	ribonucleoside binding
x	0034062	molecular_function	5'-3' RNA polymerase activity
x	0046677	biological_process	response to antibiotic
X	0000428	cellular_component	DNA-directed RNA polymerase complex
X	0003677	molecular_function	DNA binding
X	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
X	0006351	biological_process	DNA-templated transcription
X	0016779	molecular_function	nucleotidyltransferase activity
X	0032549	molecular_function	ribonucleoside binding
X	0034062	molecular_function	5'-3' RNA polymerase activity
X	0046677	biological_process	response to antibiotic
y	0000287	molecular_function	magnesium ion binding
y	0000428	cellular_component	DNA-directed RNA polymerase complex
y	0003677	molecular_function	DNA binding
y	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
y	0005515	molecular_function	protein binding
y	0006351	biological_process	DNA-templated transcription
y	0008270	molecular_function	zinc ion binding
y	0016779	molecular_function	nucleotidyltransferase activity
y	0034062	molecular_function	5'-3' RNA polymerase activity
y	0046677	biological_process	response to antibiotic
y	0046872	molecular_function	metal ion binding
Y	0000287	molecular_function	magnesium ion binding
Y	0000428	cellular_component	DNA-directed RNA polymerase complex
Y	0003677	molecular_function	DNA binding
Y	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
Y	0005515	molecular_function	protein binding
Y	0006351	biological_process	DNA-templated transcription
Y	0008270	molecular_function	zinc ion binding
Y	0016779	molecular_function	nucleotidyltransferase activity
Y	0034062	molecular_function	5'-3' RNA polymerase activity
Y	0046677	biological_process	response to antibiotic
Y	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN Y 1201

Chain	Residue
Y	CYS818
Y	CYS892
Y	CYS899
Y	CYS902

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site_id	AC2
Number of Residues	5
Details	binding site for residue ZN y 1201

Chain	Residue
y	CYS818
y	CYS892
y	VAL898
y	CYS899
y	CYS902

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Functional Information from PROSITE/UniProt

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV

Chain	Residue	Details
X	GLY922-VAL934

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01322

Chain	Residue	Details
Y	CYS60
Y	CYS899
Y	CYS902
y	CYS60
y	CYS62
y	CYS75
y	CYS78
y	ASP449
y	ASP451
y	ASP453
y	CYS818
Y	CYS62
y	CYS892
y	CYS899
y	CYS902
Y	CYS75
Y	CYS78
Y	ASP449
Y	ASP451
Y	ASP453
Y	CYS818
Y	CYS892

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