Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008134 | molecular_function | transcription factor binding |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 701 |
| Chain | Residue |
| A | ILE435 |
| A | HIS437 |
| A | SER438 |
| A | SER439 |
| A | ARG494 |
| A | HOH808 |
| A | HOH817 |
| A | HOH846 |
| A | HOH941 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 702 |
| Chain | Residue |
| A | ARG415 |
| A | PHE478 |
| A | ARG483 |
| A | QHT712 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 703 |
| Chain | Residue |
| A | ASN482 |
| A | ARG483 |
| A | ASP526 |
| A | HOH801 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 704 |
| Chain | Residue |
| A | ARG354 |
| A | LEU355 |
| A | ASP357 |
| A | HIS552 |
| A | LEU578 |
| A | HOH912 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 705 |
| Chain | Residue |
| A | ASP479 |
| A | THR481 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 706 |
| Chain | Residue |
| A | ARG494 |
| A | ASN495 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 707 |
| Chain | Residue |
| A | MET456 |
| A | LEU457 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue DMS A 708 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 709 |
| Chain | Residue |
| A | PHE546 |
| A | GLN563 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 710 |
| Chain | Residue |
| A | ARG415 |
| A | QHT712 |
| A | HOH858 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 711 |
| Chain | Residue |
| A | TYR525 |
| A | GLN530 |
| A | SER555 |
| A | QHT712 |
| site_id | AD3 |
| Number of Residues | 16 |
| Details | binding site for residue QHT A 712 |
| Chain | Residue |
| A | TYR334 |
| A | SER363 |
| A | ASN382 |
| A | ARG415 |
| A | GLY462 |
| A | ARG483 |
| A | SER508 |
| A | SER555 |
| A | ALA556 |
| A | TYR572 |
| A | SER602 |
| A | GLY603 |
| A | DMS702 |
| A | DMS710 |
| A | DMS711 |
| A | HOH858 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"Kelch 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 6"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Sensor for electrophilic agents","evidences":[{"source":"PubMed","id":"20498371","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-cGMP-cysteine","evidences":[{"source":"PubMed","id":"20498371","evidenceCode":"ECO:0000269"}]} |
