6ZCW
Crystal structure of lanthanide-dependent alcohol dehydrogenase PedH from Pseudomonas putida KT2440
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0020037 | molecular_function | heme binding |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052934 | molecular_function | alcohol dehydrogenase (cytochrome c) activity |
| A | 0070968 | molecular_function | pyrroloquinoline quinone binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue PQQ A 1201 |
| Chain | Residue |
| A | GLN87 |
| A | ALA261 |
| A | TRP263 |
| A | ASN281 |
| A | ASP323 |
| A | ASP325 |
| A | ARG350 |
| A | LEU413 |
| A | ASN417 |
| A | TRP493 |
| A | GLY556 |
| A | CYS131 |
| A | ALA557 |
| A | PR1202 |
| A | HOH1306 |
| A | HOH1344 |
| A | HOH1547 |
| A | CYS132 |
| A | ARG137 |
| A | SER181 |
| A | ALA196 |
| A | GLY197 |
| A | GLY198 |
| A | GLU199 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PR A 1202 |
| Chain | Residue |
| A | GLU199 |
| A | ASN281 |
| A | ASP323 |
| A | ASP325 |
| A | PQQ1201 |
Functional Information from PROSITE/UniProt
| site_id | PS00364 |
| Number of Residues | 22 |
| Details | BACTERIAL_PQQ_2 Bacterial quinoprotein dehydrogenases signature 2. WlggyYDpetNLILFgtGnpAP |
| Chain | Residue | Details |
| A | TRP263-PRO284 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q9Z4J7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2020","firstPage":"7836","lastPage":"7842","volume":"10","journal":"ACS Catal.","title":"Engineered PQQ-Dependent Alcohol Dehydrogenase for the Oxidation of 5-(Hydroxymethyl)furoic Acid.","authors":["Wehrmann M.","Elsayed E.M.","Kobbing S.","Bendz L.","Lepak A.","Schwabe J.","Wierckx N.","Bange G.","Klebensberger J."],"citationCrossReferences":[{"database":"DOI","id":"10.1021/acscatal.0c01789"}]}},{"source":"PDB","id":"6ZCV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZCW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
