6ZCV

Crystal structure of lanthanide-dependent alcohol dehydrogenase PedH from Pseudomonas putida KT2440

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0016020	cellular_component	membrane
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0030288	cellular_component	outer membrane-bounded periplasmic space

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 701

Chain	Residue
A	ASN188
A	LYS190
A	PRO305
A	ASP306
A	HOH1278

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site_id	AC2
Number of Residues	24
Details	binding site for residue PQQ A 702

Chain	Residue
A	ARG137
A	SER181
A	ALA196
A	GLY197
A	GLY198
A	GLU199
A	ALA261
A	TRP263
A	ASN281
A	ASP323
A	ASP325
A	ARG350
A	ASN417
A	TRP493
A	GLY556
A	ALA557
A	PR703
A	GOL704
A	HOH908
A	HOH1046
A	GLN87
A	CYS131
A	CYS132
A	ILE135

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site_id	AC3
Number of Residues	5
Details	binding site for residue PR A 703

Chain	Residue
A	GLU199
A	ASN281
A	ASP323
A	ASP325
A	PQQ702

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site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 704

Chain	Residue
A	CYS132
A	GLU199
A	ASP323
A	ARG350
A	PQQ702
A	HOH1094

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Functional Information from PROSITE/UniProt

site_id	PS00364
Number of Residues	22
Details	BACTERIAL_PQQ_2 Bacterial quinoprotein dehydrogenases signature 2. WlggyYDpetNLILFgtGnpAP

Chain	Residue	Details
A	TRP263-PRO284

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q9Z4J7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2020","firstPage":"7836","lastPage":"7842","volume":"10","journal":"ACS Catal.","title":"Engineered PQQ-Dependent Alcohol Dehydrogenase for the Oxidation of 5-(Hydroxymethyl)furoic Acid.","authors":["Wehrmann M.","Elsayed E.M.","Kobbing S.","Bendz L.","Lepak A.","Schwabe J.","Wierckx N.","Bange G.","Klebensberger J."],"citationCrossReferences":[{"database":"DOI","id":"10.1021/acscatal.0c01789"}]}},{"source":"PDB","id":"6ZCV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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