6ZBQ
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue QE2 A 401 |
| Chain | Residue |
| A | PHE259 |
| A | GLU321 |
| A | VAL323 |
| A | LEU260 |
| A | GLY261 |
| A | ILE262 |
| A | MET310 |
| A | VAL316 |
| A | VAL318 |
| A | LEU319 |
| A | ARG320 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue QE2 B 401 |
| Chain | Residue |
| A | GLY274 |
| A | TYR277 |
| B | PHE259 |
| B | LEU260 |
| B | GLY261 |
| B | ILE262 |
| B | VAL316 |
| B | LEU319 |
| B | ARG320 |
| B | VAL323 |
| B | HIS324 |
| B | HOH501 |
| B | HOH539 |
| B | HOH552 |
| B | HOH560 |
