6Z8N

Crystal structure of the neurotensin receptor 1 in complex with the small-molecule full agonist SRI-9829

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0004930	molecular_function	G protein-coupled receptor activity
AAA	0007186	biological_process	G protein-coupled receptor signaling pathway
AAA	0016020	cellular_component	membrane
AAA	0016492	molecular_function	G protein-coupled neurotensin receptor activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	TRANSMEM: Helical; Name=1

Chain	Residue	Details
AAA	ALA69-LEU89

---

site_id	SWS_FT_FI2
Number of Residues	79
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:24453215

Chain	Residue	Details
AAA	ALA90-ASP103
AAA	GLU166-ARG185
AAA	ALA261-VAL326

---

site_id	SWS_FT_FI3
Number of Residues	19
Details	TRANSMEM: Helical; Name=2

Chain	Residue	Details
AAA	TYR104-VAL123

---

site_id	SWS_FT_FI4
Number of Residues	64
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:24453215

Chain	Residue	Details
AAA	ASP124-LYS143
AAA	THR207-ARG235
AAA	TYR349-PRO366

---

site_id	SWS_FT_FI5
Number of Residues	21
Details	TRANSMEM: Helical; Name=3

Chain	Residue	Details
AAA	GLY144-VAL165

---

site_id	SWS_FT_FI6
Number of Residues	20
Details	TRANSMEM: Helical; Name=4

Chain	Residue	Details
AAA	THR186-PHE206

---

site_id	SWS_FT_FI7
Number of Residues	24
Details	TRANSMEM: Helical; Name=5

Chain	Residue	Details
AAA	VAL236-ALA260

---

site_id	SWS_FT_FI8
Number of Residues	21
Details	TRANSMEM: Helical; Name=6

Chain	Residue	Details
AAA	ARG327-HIS348

---

site_id	SWS_FT_FI9
Number of Residues	20
Details	TRANSMEM: Helical; Name=7

Chain	Residue	Details
AAA	ILE367-GLU387

---