Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003774 | molecular_function | cytoskeletal motor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016459 | cellular_component | myosin complex |
| A | 0051015 | molecular_function | actin filament binding |
| B | 0003774 | molecular_function | cytoskeletal motor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016459 | cellular_component | myosin complex |
| B | 0051015 | molecular_function | actin filament binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 801 |
| Chain | Residue |
| A | SER181 |
| A | THR186 |
| A | GOL817 |
| A | HOH1108 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 802 |
| Chain | Residue |
| A | ILE656 |
| A | EDO804 |
| A | ALA125 |
| A | VAL126 |
| A | ASN127 |
| A | ALA183 |
| A | CYS655 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 803 |
| Chain | Residue |
| A | ASN475 |
| A | LEU478 |
| A | GLN479 |
| A | TYR573 |
| A | ARG654 |
| A | ASN679 |
| A | HOH988 |
| A | HOH1176 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 804 |
| Chain | Residue |
| A | ILE115 |
| A | TYR135 |
| A | GLY184 |
| A | GLU187 |
| A | ASN188 |
| A | MG802 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 805 |
| Chain | Residue |
| A | TYR37 |
| A | PRO39 |
| A | VAL65 |
| A | HOH1286 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 806 |
| Chain | Residue |
| A | GLU89 |
| A | VAL151 |
| A | ALA152 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 807 |
| Chain | Residue |
| A | HIS485 |
| A | LYS488 |
| A | GLU646 |
| A | THR648 |
| A | PRO650 |
| A | HOH1204 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 808 |
| Chain | Residue |
| A | TYR573 |
| A | ARG677 |
| A | LEU682 |
| A | GLU683 |
| A | GOL813 |
| A | HOH911 |
| A | HOH934 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 809 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 810 |
| Chain | Residue |
| A | ARG202 |
| A | ASN248 |
| A | PHE252 |
| A | HOH1259 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 811 |
| Chain | Residue |
| A | ASP40 |
| A | LYS42 |
| A | TYR163 |
| A | ARG164 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 812 |
| Chain | Residue |
| A | SER266 |
| A | ARG267 |
| A | PHE270 |
| A | GLN271 |
| A | SER272 |
| A | GLU275 |
| A | HOH1251 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 813 |
| Chain | Residue |
| A | ASP509 |
| A | LYS557 |
| A | GLU683 |
| A | ARG686 |
| A | EDO808 |
| A | HOH903 |
| A | HOH974 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 814 |
| Chain | Residue |
| A | HIS485 |
| A | ASN649 |
| A | PRO650 |
| A | HIS651 |
| A | HOH945 |
| A | HOH978 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 815 |
| Chain | Residue |
| A | SER165 |
| A | ASP169 |
| A | HOH929 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 816 |
| Chain | Residue |
| A | TRP36 |
| A | TYR47 |
| A | PHE103 |
| A | ARG107 |
| A | ASP669 |
| A | HOH1078 |
| A | HOH1254 |
| B | ASN765 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 817 |
| Chain | Residue |
| A | SER181 |
| A | GLY182 |
| A | ALA183 |
| A | GLY184 |
| A | THR186 |
| A | GLU187 |
| A | MG801 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 801 |
| Chain | Residue |
| B | GLU180 |
| B | SER181 |
| B | ALA183 |
| B | GLY184 |
| B | LYS185 |
| B | EDO812 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 802 |
| Chain | Residue |
| B | ASN127 |
| B | ALA183 |
| B | CYS655 |
| B | EDO804 |
| B | ALA125 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 803 |
| Chain | Residue |
| B | ARG232 |
| B | ASN660 |
| B | HOH1075 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 804 |
| Chain | Residue |
| B | ILE115 |
| B | GLY184 |
| B | GLU187 |
| B | ASN188 |
| B | MG802 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 805 |
| Chain | Residue |
| B | GLU89 |
| B | ASN149 |
| B | VAL151 |
| B | ALA152 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 806 |
| Chain | Residue |
| B | ASN475 |
| B | GLN479 |
| B | ARG654 |
| B | CYS678 |
| B | ASN679 |
| B | HOH1153 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 807 |
| Chain | Residue |
| B | HIS485 |
| B | LYS488 |
| B | GLU646 |
| B | THR648 |
| B | PRO650 |
| B | HOH1137 |
| B | HOH1162 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 808 |
| Chain | Residue |
| B | PEG819 |
| B | HOH970 |
| B | HOH992 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 809 |
| Chain | Residue |
| B | ARG202 |
| B | ASN248 |
| B | PHE252 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 810 |
| Chain | Residue |
| A | GLN171 |
| B | GLN521 |
| B | PRO523 |
| B | HIS550 |
| B | HOH946 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 811 |
| Chain | Residue |
| A | ARG520 |
| A | GLN521 |
| A | HOH1153 |
| B | ASP169 |
| B | ARG170 |
| site_id | AF2 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 812 |
| Chain | Residue |
| B | SER181 |
| B | GLY182 |
| B | ALA183 |
| B | GLY184 |
| B | LYS185 |
| B | THR186 |
| B | GLU187 |
| B | MG801 |
| B | HOH1297 |
| site_id | AF3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 813 |
| Chain | Residue |
| A | ASN765 |
| A | HOH948 |
| B | TRP36 |
| B | TYR47 |
| B | ARG107 |
| B | HOH1084 |
| B | HOH1088 |
| B | HOH1288 |
| site_id | AF4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 814 |
| Chain | Residue |
| B | ILE696 |
| B | ASP700 |
| B | ARG704 |
| B | TYR705 |
| B | HOH975 |
| B | HOH1005 |
| B | HOH1045 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 815 |
| Chain | Residue |
| A | GLY87 |
| A | GLN112 |
| B | ARG758 |
| B | HOH910 |
| B | HOH921 |
| B | HOH1413 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 816 |
| Chain | Residue |
| B | TYR135 |
| B | VAL140 |
| B | LYS191 |
| B | GLN194 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 817 |
| Chain | Residue |
| B | HIS485 |
| B | LEU489 |
| B | ASN649 |
| B | PRO650 |
| B | HIS651 |
| B | HOH1012 |
| site_id | AF8 |
| Number of Residues | 9 |
| Details | binding site for residue PGE B 818 |
| Chain | Residue |
| A | ARG758 |
| A | LEU762 |
| A | HOH1180 |
| B | ASP86 |
| B | GLY87 |
| B | GLU89 |
| B | ARG109 |
| B | GLN112 |
| B | HOH971 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 819 |
| Chain | Residue |
| B | SER165 |
| B | ASP168 |
| B | ASP169 |
| B | EDO808 |
| B | HOH1004 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 104 |
| Details | Domain: {"description":"Myosin N-terminal SH3-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU01190","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 72 |
| Details | Region: {"description":"Actin-binding"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6,N6-dimethyllysine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 8 |
| Details | M-CSA 534 |
| Chain | Residue | Details |
| A | SER181 | proton acceptor, proton donor, proton relay |
| A | GLY182 | electrostatic stabiliser |
| A | THR186 | metal ligand |
| A | ASN233 | electrostatic stabiliser |
| A | SER236 | proton acceptor, proton donor, proton relay |
| A | SER237 | metal ligand |
| A | GLY457 | electrostatic stabiliser |
| A | GLU459 | electrostatic stabiliser, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 8 |
| Details | M-CSA 534 |
| Chain | Residue | Details |
| B | SER181 | proton acceptor, proton donor, proton relay |
| B | GLY182 | electrostatic stabiliser |
| B | THR186 | metal ligand |
| B | ASN233 | electrostatic stabiliser |
| B | SER236 | proton acceptor, proton donor, proton relay |
| B | SER237 | metal ligand |
| B | GLY457 | electrostatic stabiliser |
| B | GLU459 | electrostatic stabiliser, proton acceptor, proton donor |
