Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6Z6H

HDAC-DC

Functional Information from GO Data
ChainGOidnamespacecontents
A0000118cellular_componenthistone deacetylase complex
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0003682molecular_functionchromatin binding
A0004407molecular_functionhistone deacetylase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0006325biological_processchromatin organization
A0006355biological_processregulation of DNA-templated transcription
A0008270molecular_functionzinc ion binding
A0010621biological_processnegative regulation of transcription by transcription factor localization
A0016787molecular_functionhydrolase activity
A0040029biological_processepigenetic regulation of gene expression
A0042802molecular_functionidentical protein binding
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0070823cellular_componentHDA1 complex
B0000118cellular_componenthistone deacetylase complex
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0003682molecular_functionchromatin binding
B0004407molecular_functionhistone deacetylase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0006325biological_processchromatin organization
B0006355biological_processregulation of DNA-templated transcription
B0008270molecular_functionzinc ion binding
B0010621biological_processnegative regulation of transcription by transcription factor localization
B0016787molecular_functionhydrolase activity
B0040029biological_processepigenetic regulation of gene expression
B0042802molecular_functionidentical protein binding
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0070823cellular_componentHDA1 complex
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0003677molecular_functionDNA binding
C0003682molecular_functionchromatin binding
C0004407molecular_functionhistone deacetylase activity
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006325biological_processchromatin organization
C0006338biological_processchromatin remodeling
C0006357biological_processregulation of transcription by RNA polymerase II
C0031047biological_processregulatory ncRNA-mediated gene silencing
C0070823cellular_componentHDA1 complex
D0005634cellular_componentnucleus
D0070823cellular_componentHDA1 complex
F0000118cellular_componenthistone deacetylase complex
F0000122biological_processnegative regulation of transcription by RNA polymerase II
F0003682molecular_functionchromatin binding
F0004407molecular_functionhistone deacetylase activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0006325biological_processchromatin organization
F0006355biological_processregulation of DNA-templated transcription
F0008270molecular_functionzinc ion binding
F0010621biological_processnegative regulation of transcription by transcription factor localization
F0016787molecular_functionhydrolase activity
F0040029biological_processepigenetic regulation of gene expression
F0042802molecular_functionidentical protein binding
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0070823cellular_componentHDA1 complex
G0000118cellular_componenthistone deacetylase complex
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0003682molecular_functionchromatin binding
G0004407molecular_functionhistone deacetylase activity
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0006325biological_processchromatin organization
G0006355biological_processregulation of DNA-templated transcription
G0008270molecular_functionzinc ion binding
G0010621biological_processnegative regulation of transcription by transcription factor localization
G0016787molecular_functionhydrolase activity
G0040029biological_processepigenetic regulation of gene expression
G0042802molecular_functionidentical protein binding
G0045944biological_processpositive regulation of transcription by RNA polymerase II
G0070823cellular_componentHDA1 complex
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0003677molecular_functionDNA binding
I0003682molecular_functionchromatin binding
I0004407molecular_functionhistone deacetylase activity
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0006325biological_processchromatin organization
I0006338biological_processchromatin remodeling
I0006357biological_processregulation of transcription by RNA polymerase II
I0031047biological_processregulatory ncRNA-mediated gene silencing
I0070823cellular_componentHDA1 complex
J0005634cellular_componentnucleus
J0070823cellular_componentHDA1 complex
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 801
ChainResidue
AHIS205
AASP245
AGLU375
AGLY376

site_idAC2
Number of Residues5
Detailsbinding site for residue ZN B 801
ChainResidue
BHIS205
BHIS206
BASP245
BHIS247
BASP338

site_idAC3
Number of Residues3
Detailsbinding site for residue ZN F 801
ChainResidue
FHIS205
FHIS206
FHIS247

site_idAC4
Number of Residues4
Detailsbinding site for residue ZN G 801
ChainResidue
GHIS205
GASP245
GHIS247
GASP338

Functional Information from PROSITE/UniProt
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. KYQIESSKAAESAQTL
ChainResidueDetails
CLYS570-LEU585

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000250
ChainResidueDetails
BHIS206
GHIS206

223166

PDB entries from 2024-07-31

PDB statisticsPDBj update infoContact PDBjnumon