6Z6A

Keap1 macrocycle complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008134	molecular_function	transcription factor binding
A	0016567	biological_process	protein ubiquitination
A	0031463	cellular_component	Cul3-RING ubiquitin ligase complex
B	0008134	molecular_function	transcription factor binding
B	0016567	biological_process	protein ubiquitination
B	0031463	cellular_component	Cul3-RING ubiquitin ligase complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue Q9E A 701

Chain	Residue
A	TYR334
A	GLY603
A	CL703
A	HOH815
B	GLY386
A	SER363
A	GLY364
A	ASN382
A	ARG415
A	ALA556
A	TYR572
A	PHE577
A	SER602

---

site_id	AC2
Number of Residues	2
Details	binding site for residue NA A 702

Chain	Residue
A	TYR473
A	TYR537

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CL A 703

Chain	Residue
A	ARG415
A	Q9E701
A	HOH815

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	90
Details	Repeat: {"description":"Kelch 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	100
Details	Repeat: {"description":"Kelch 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	92
Details	Repeat: {"description":"Kelch 3"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	92
Details	Repeat: {"description":"Kelch 4"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	92
Details	Repeat: {"description":"Kelch 5"}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Sensor for electrophilic agents","evidences":[{"source":"UniProtKB","id":"Q9Z2X8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"S-cGMP-cysteine","evidences":[{"source":"UniProtKB","id":"Q9Z2X8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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