6Z65
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a di-adenosine derivative
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003951 | molecular_function | NAD+ kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006741 | biological_process | NADP biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0019674 | biological_process | NAD metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue CIT A 301 |
| Chain | Residue |
| A | TYR100 |
| A | HIS173 |
| A | ARG247 |
| A | PHE251 |
| A | PRO252 |
| A | PHE253 |
| A | ARG256 |
| A | HOH442 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue Q9N A 302 |
| Chain | Residue |
| A | HIS71 |
| A | PHE74 |
| A | TYR75 |
| A | ASN122 |
| A | GLU123 |
| A | ASP150 |
| A | SER158 |
| A | THR161 |
| A | ALA162 |
| A | TYR163 |
| A | SER166 |
| A | ALA185 |
| A | TYR192 |
| A | HOH420 |
| A | HOH430 |
| A | HOH433 |
| A | HOH441 |
| A | ASP45 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00361, ECO:0000269|PubMed:17686780 |
| Chain | Residue | Details |
| A | ASP45 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00361, ECO:0000269|PubMed:17686780 |
| Chain | Residue | Details |
| A | ASP45 | |
| A | GLY46 | |
| A | ASN122 | |
| A | SER158 | |
| A | THR161 | |
| A | HIS223 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00361 |
| Chain | Residue | Details |
| A | ARG148 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:17686780 |
| Chain | Residue | Details |
| A | ASP150 |
