6Z3D

L-FerritinMSA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005764	cellular_component	lysosome
A	0005776	cellular_component	autophagosome
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0044754	cellular_component	autolysosome
A	0046872	molecular_function	metal ion binding
A	0070288	cellular_component	ferritin complex
A	0071682	cellular_component	endocytic vesicle lumen
B	0005506	molecular_function	iron ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005764	cellular_component	lysosome
B	0005776	cellular_component	autophagosome
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0031410	cellular_component	cytoplasmic vesicle
B	0044754	cellular_component	autolysosome
B	0046872	molecular_function	metal ion binding
B	0070288	cellular_component	ferritin complex
B	0071682	cellular_component	endocytic vesicle lumen
C	0005506	molecular_function	iron ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005764	cellular_component	lysosome
C	0005776	cellular_component	autophagosome
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0031410	cellular_component	cytoplasmic vesicle
C	0044754	cellular_component	autolysosome
C	0046872	molecular_function	metal ion binding
C	0070288	cellular_component	ferritin complex
C	0071682	cellular_component	endocytic vesicle lumen
D	0005506	molecular_function	iron ion binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005764	cellular_component	lysosome
D	0005776	cellular_component	autophagosome
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0031410	cellular_component	cytoplasmic vesicle
D	0044754	cellular_component	autolysosome
D	0046872	molecular_function	metal ion binding
D	0070288	cellular_component	ferritin complex
D	0071682	cellular_component	endocytic vesicle lumen
E	0005506	molecular_function	iron ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005764	cellular_component	lysosome
E	0005776	cellular_component	autophagosome
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0031410	cellular_component	cytoplasmic vesicle
E	0044754	cellular_component	autolysosome
E	0046872	molecular_function	metal ion binding
E	0070288	cellular_component	ferritin complex
E	0071682	cellular_component	endocytic vesicle lumen
F	0005506	molecular_function	iron ion binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0005764	cellular_component	lysosome
F	0005776	cellular_component	autophagosome
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0031410	cellular_component	cytoplasmic vesicle
F	0044754	cellular_component	autolysosome
F	0046872	molecular_function	metal ion binding
F	0070288	cellular_component	ferritin complex
F	0071682	cellular_component	endocytic vesicle lumen

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ACT A 201

Chain	Residue
A	LEU25
A	ACT202
A	HOH340
B	ARG60

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site_id	AC2
Number of Residues	5
Details	binding site for residue ACT A 202

Chain	Residue
A	ARG60
A	ACT201
A	HOH326
B	LEU25
B	TYR29

---

site_id	AC3
Number of Residues	5
Details	binding site for residue ACT C 201

Chain	Residue
C	ARG60
C	HOH341
D	LEU25
D	TYR29
D	ACT201

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site_id	AC4
Number of Residues	3
Details	binding site for residue ACT D 201

Chain	Residue
C	LEU25
C	ACT201
D	ARG60

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site_id	AC5
Number of Residues	4
Details	binding site for residue ACT E 201

Chain	Residue
E	ARG60
E	ACT202
F	LEU25
F	TYR29

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ACT E 202

Chain	Residue
E	LEU25
E	ACT201
E	HOH349
F	ARG60

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Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshYLdkevklIK

Chain	Residue	Details
A	ASP123-LYS143

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site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLefQNdRgGR

Chain	Residue	Details
A	GLU58-ARG76

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00085

Chain	Residue	Details
A	GLU54
B	GLU64
C	GLU54
C	GLU57
C	GLU58
C	GLU61
C	GLU64
D	GLU54
D	GLU57
D	GLU58
D	GLU61
A	GLU57
D	GLU64
E	GLU54
E	GLU57
E	GLU58
E	GLU61
E	GLU64
F	GLU54
F	GLU57
F	GLU58
F	GLU61
A	GLU58
F	GLU64
A	GLU61
A	GLU64
B	GLU54
B	GLU57
B	GLU58
B	GLU61

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