6Z2Q
Crystal structure of wild type OgpA from Akkermansia muciniphila in complex with an O-glycopeptide (GalGalNAc-TS) product
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. GMAHELGHGL |
| Chain | Residue | Details |
| A | GLY202-LEU211 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Critical for inhibition of translation, possibly due to its role in mediating the interaction with bacterial 23S rRNA => ECO:0000269|PubMed:36997647 |
| Chain | Residue | Details |
| D | LYS-7 | |
| D | ARG-5 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Critical for inhibition of translation, possibly due to its role in mediating the interaction with bacterial 23S rRNA and rplV/50S ribosomal protein L22 => ECO:0000269|PubMed:36997646, ECO:0000269|PubMed:36997647 |
| Chain | Residue | Details |
| D | ARG0 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (GalNAc...) serine => ECO:0000269|PubMed:9736738 |
| Chain | Residue | Details |
| D | SER-2 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:36997646, ECO:0000269|PubMed:8325867, ECO:0000269|PubMed:9736738, ECO:0000269|PubMed:9888811, ECO:0000312|PDB:8AKN, ECO:0000312|PDB:8AM9, ECO:0000312|PDB:8ANA |
| Chain | Residue | Details |
| D | THR2 |
