6Z1Y
Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0030598 | molecular_function | rRNA N-glycosylase activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017148 | biological_process | negative regulation of translation |
| B | 0030598 | molecular_function | rRNA N-glycosylase activity |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0090729 | molecular_function | toxin activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0017148 | biological_process | negative regulation of translation |
| C | 0030598 | molecular_function | rRNA N-glycosylase activity |
| C | 0035821 | biological_process | modulation of process of another organism |
| C | 0090729 | molecular_function | toxin activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0017148 | biological_process | negative regulation of translation |
| D | 0030598 | molecular_function | rRNA N-glycosylase activity |
| D | 0035821 | biological_process | modulation of process of another organism |
| D | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 301 |
| Chain | Residue |
| A | ALA118 |
| A | ASN145 |
| A | HOH459 |
| D | SER12 |
| D | HOH458 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 301 |
| Chain | Residue |
| D | HOH420 |
| B | ASP176 |
| D | GLN208 |
| D | THR226 |
| D | HOH320 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 302 |
| Chain | Residue |
| B | ALA118 |
| B | ASN145 |
| B | HOH443 |
| B | HOH551 |
| C | SER12 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 301 |
| Chain | Residue |
| C | ASN244 |
| C | ASN245 |
| C | HOH517 |
| D | ARG243 |
| D | MET246 |
| D | HOH418 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 302 |
| Chain | Residue |
| C | SER191 |
| C | VAL214 |
| C | HOH470 |
| C | HOH529 |
| C | HOH532 |
| C | HOH546 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 303 |
| Chain | Residue |
| C | ARG243 |
| C | MET246 |
| C | HOH527 |
| D | ASN244 |
| D | ASN245 |
Functional Information from PROSITE/UniProt
| site_id | PS00275 |
| Number of Residues | 17 |
| Details | SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqSTsEAARYKfIEqqI |
| Chain | Residue | Details |
| A | ILE155-ILE171 |
