6Z16
Structure of the Mrp antiporter complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006814 | biological_process | sodium ion transport |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0098662 | biological_process | obsolete inorganic cation transmembrane transport |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| C | 0005886 | cellular_component | plasma membrane |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| D | 0015297 | molecular_function | antiporter activity |
| D | 0016020 | cellular_component | membrane |
| D | 0042773 | biological_process | ATP synthesis coupled electron transport |
| D | 0055085 | biological_process | transmembrane transport |
| D | 1902600 | biological_process | proton transmembrane transport |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0006812 | biological_process | monoatomic cation transport |
| E | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
| E | 0015297 | molecular_function | antiporter activity |
| E | 0016020 | cellular_component | membrane |
| E | 0055085 | biological_process | transmembrane transport |
| E | 0098655 | biological_process | monoatomic cation transmembrane transport |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0006811 | biological_process | monoatomic ion transport |
| F | 0015075 | molecular_function | monoatomic ion transmembrane transporter activity |
| F | 0015297 | molecular_function | antiporter activity |
| F | 0015385 | molecular_function | sodium:proton antiporter activity |
| F | 0016020 | cellular_component | membrane |
| F | 0034220 | biological_process | monoatomic ion transmembrane transport |
| F | 0035725 | biological_process | sodium ion transmembrane transport |
| G | 0015297 | molecular_function | antiporter activity |
| G | 0015385 | molecular_function | sodium:proton antiporter activity |
| G | 0016020 | cellular_component | membrane |
| G | 0035725 | biological_process | sodium ion transmembrane transport |
| G | 0098662 | biological_process | obsolete inorganic cation transmembrane transport |
| a | 0005886 | cellular_component | plasma membrane |
| a | 0006811 | biological_process | monoatomic ion transport |
| a | 0006814 | biological_process | sodium ion transport |
| a | 0015297 | molecular_function | antiporter activity |
| a | 0016020 | cellular_component | membrane |
| a | 0098662 | biological_process | obsolete inorganic cation transmembrane transport |
| a | 1902600 | biological_process | proton transmembrane transport |
| b | 0005886 | cellular_component | plasma membrane |
| c | 0005886 | cellular_component | plasma membrane |
| d | 0005886 | cellular_component | plasma membrane |
| d | 0008137 | molecular_function | NADH dehydrogenase (ubiquinone) activity |
| d | 0015297 | molecular_function | antiporter activity |
| d | 0016020 | cellular_component | membrane |
| d | 0042773 | biological_process | ATP synthesis coupled electron transport |
| d | 0055085 | biological_process | transmembrane transport |
| d | 1902600 | biological_process | proton transmembrane transport |
| e | 0005886 | cellular_component | plasma membrane |
| e | 0006812 | biological_process | monoatomic cation transport |
| e | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
| e | 0015297 | molecular_function | antiporter activity |
| e | 0016020 | cellular_component | membrane |
| e | 0055085 | biological_process | transmembrane transport |
| e | 0098655 | biological_process | monoatomic cation transmembrane transport |
| f | 0005886 | cellular_component | plasma membrane |
| f | 0006811 | biological_process | monoatomic ion transport |
| f | 0015075 | molecular_function | monoatomic ion transmembrane transporter activity |
| f | 0015297 | molecular_function | antiporter activity |
| f | 0015385 | molecular_function | sodium:proton antiporter activity |
| f | 0016020 | cellular_component | membrane |
| f | 0034220 | biological_process | monoatomic ion transmembrane transport |
| f | 0035725 | biological_process | sodium ion transmembrane transport |
| g | 0015297 | molecular_function | antiporter activity |
| g | 0015385 | molecular_function | sodium:proton antiporter activity |
| g | 0016020 | cellular_component | membrane |
| g | 0035725 | biological_process | sodium ion transmembrane transport |
| g | 0098662 | biological_process | obsolete inorganic cation transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue PTY A 901 |
| Chain | Residue |
| A | VAL515 |
| A | LEU516 |
| A | VAL520 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PTY A 902 |
| Chain | Residue |
| A | TRP300 |
| A | THR301 |
| A | ALA446 |
| A | TRP448 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue PTY A 903 |
| Chain | Residue |
| A | HIS719 |
| B | LEU42 |
| B | GLY46 |
| B | ASP140 |
| F | PHE75 |
| F | PHE78 |
| F | VAL83 |
| F | VAL84 |
| A | LEU714 |
| A | LEU715 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue PTY A 904 |
| Chain | Residue |
| A | LEU43 |
| A | PRO46 |
| A | PHE47 |
| A | LYS50 |
| A | CYS51 |
| A | LEU145 |
| A | PTY905 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PTY A 905 |
| Chain | Residue |
| A | ASN138 |
| A | PTY904 |
| D | PRO367 |
| D | TRP371 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PTY A 906 |
| Chain | Residue |
| A | PRO232 |
| A | ILE235 |
| A | PRO236 |
| D | ILE405 |
| D | PHE406 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue PTY A 907 |
| Chain | Residue |
| A | VAL654 |
| A | THR665 |
| A | ILE668 |
| A | LYS670 |
| A | SER671 |
| F | ARG30 |
| F | PTY1801 |
| F | PTY1802 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue K A 908 |
| Chain | Residue |
| A | GLN702 |
| C | HIS37 |
| C | HIS40 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue PTY B 201 |
| Chain | Residue |
| B | ALA13 |
| B | VAL14 |
| E | TRP101 |
| e | LEU7 |
| e | PHE44 |
| e | PHE45 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue K C 201 |
| Chain | Residue |
| C | HIS40 |
| C | SER80 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue PTY D 501 |
| Chain | Residue |
| D | PHE21 |
| D | PHE22 |
| D | HIS25 |
| D | TRP28 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue PTY D 502 |
| Chain | Residue |
| D | TYR98 |
| D | PHE447 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue PTY D 503 |
| Chain | Residue |
| D | LEU455 |
| D | ALA458 |
| D | TYR459 |
| D | GLY462 |
| D | PHE465 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue PTY E 201 |
| Chain | Residue |
| E | LEU7 |
| E | PHE44 |
| E | PHE45 |
| E | HIS46 |
| b | ALA13 |
| b | VAL14 |
| e | TRP101 |
| site_id | AD6 |
| Number of Residues | 15 |
| Details | binding site for residue PTY F 1801 |
| Chain | Residue |
| A | GLY658 |
| A | SER671 |
| A | LEU673 |
| A | THR674 |
| A | VAL677 |
| A | TYR684 |
| A | ALA685 |
| A | LEU714 |
| A | PTY907 |
| F | VAL21 |
| F | VAL22 |
| F | THR27 |
| F | ARG30 |
| F | MET37 |
| F | PHE75 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue PTY F 1802 |
| Chain | Residue |
| A | TYR651 |
| A | PTY907 |
| F | ASN4 |
| F | SER11 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue PTY a 901 |
| Chain | Residue |
| a | VAL515 |
| a | LEU516 |
| a | SER519 |
| a | VAL520 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue PTY a 902 |
| Chain | Residue |
| a | TRP300 |
| a | THR301 |
| a | ALA446 |
| a | TRP448 |
| site_id | AE1 |
| Number of Residues | 9 |
| Details | binding site for residue PTY a 903 |
| Chain | Residue |
| a | HIS719 |
| b | LEU42 |
| b | GLY46 |
| f | PHE75 |
| f | PHE78 |
| f | VAL83 |
| f | VAL84 |
| a | LEU714 |
| a | LEU715 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue PTY a 904 |
| Chain | Residue |
| a | LEU43 |
| a | PRO46 |
| a | PHE47 |
| a | LYS50 |
| a | CYS51 |
| a | LEU145 |
| a | PTY905 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue PTY a 905 |
| Chain | Residue |
| a | ASN138 |
| a | PTY904 |
| d | PRO367 |
| d | TRP371 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue PTY a 906 |
| Chain | Residue |
| a | PRO232 |
| a | ILE235 |
| a | PRO236 |
| d | ILE405 |
| d | PHE406 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue PTY a 907 |
| Chain | Residue |
| a | VAL654 |
| a | THR665 |
| a | ILE668 |
| a | LYS670 |
| a | SER671 |
| a | THR674 |
| f | ARG30 |
| f | PTY1801 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue K a 908 |
| Chain | Residue |
| a | GLN702 |
| c | HIS37 |
| c | HIS40 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue K c 201 |
| Chain | Residue |
| c | HIS40 |
| c | SER80 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue PTY d 501 |
| Chain | Residue |
| d | PHE21 |
| d | PHE22 |
| d | LYS24 |
| d | HIS25 |
| d | TRP28 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue PTY d 502 |
| Chain | Residue |
| d | TYR98 |
| d | PHE447 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue PTY d 503 |
| Chain | Residue |
| d | LEU455 |
| d | ALA458 |
| d | TYR459 |
| d | GLY462 |
| d | PHE465 |
| site_id | AF2 |
| Number of Residues | 14 |
| Details | binding site for residue PTY f 1801 |
| Chain | Residue |
| a | GLY658 |
| a | SER671 |
| a | LEU673 |
| a | THR674 |
| a | VAL677 |
| a | TYR684 |
| a | LEU714 |
| a | PTY907 |
| f | VAL21 |
| f | VAL22 |
| f | THR27 |
| f | ARG30 |
| f | MET37 |
| f | PHE75 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue PTY f 1802 |
| Chain | Residue |
| a | TYR651 |
| f | SER11 |
