6Z0Z
Human wtSTING in complex with 3',3'-c-(2'FdAMP-2'FdAMP)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | binding site for residue M8T A 401 |
| Chain | Residue |
| A | SER162 |
| A | ARG232 |
| A | ILE235 |
| A | ILE235 |
| A | ARG238 |
| A | ARG238 |
| A | VAL239 |
| A | VAL239 |
| A | TYR240 |
| A | TYR240 |
| A | THR263 |
| A | SER162 |
| A | THR263 |
| A | PRO264 |
| A | PRO264 |
| A | THR267 |
| A | THR267 |
| A | HOH506 |
| A | HOH506 |
| A | HOH515 |
| A | HOH515 |
| A | HOH541 |
| A | TYR163 |
| A | HOH541 |
| A | HOH545 |
| A | HOH545 |
| A | TYR163 |
| A | GLY166 |
| A | GLY166 |
| A | TYR167 |
| A | TYR167 |
| A | ARG232 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22728660, ECO:0007744|PDB:4F5Y |
| Chain | Residue | Details |
| A | SER162 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22579474, ECO:0000269|PubMed:22705373, ECO:0000269|PubMed:22728658, ECO:0000269|PubMed:22728659, ECO:0000269|PubMed:22728660, ECO:0007744|PDB:4EF4, ECO:0007744|PDB:4EMT, ECO:0007744|PDB:4F5D, ECO:0007744|PDB:4F5Y, ECO:0007744|PDB:4F9G |
| Chain | Residue | Details |
| A | TYR167 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:37379839, ECO:0007744|PDB:8GJX |
| Chain | Residue | Details |
| A | ARG238 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22579474, ECO:0000269|PubMed:22705373, ECO:0000269|PubMed:22728658, ECO:0000269|PubMed:22728660, ECO:0007744|PDB:4EF4, ECO:0007744|PDB:4EMT, ECO:0007744|PDB:4F5Y, ECO:0007744|PDB:4F9G |
| Chain | Residue | Details |
| A | THR263 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:37832545 |
| Chain | Residue | Details |
| A | THR229 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:37832545 |
| Chain | Residue | Details |
| A | SER241 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19285439, ECO:0000269|PubMed:21074459 |
| Chain | Residue | Details |
| A | LYS150 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000250|UniProtKB:Q3TBT3 |
| Chain | Residue | Details |
| A | LYS338 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:31968013 |
| Chain | Residue | Details |
| A | LYS236 |
