6Z0V
CryoEM structure of the Chikungunya virus nsP1 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0006396 | biological_process | RNA processing |
| A | 0008174 | molecular_function | mRNA methyltransferase activity |
| A | 0016556 | biological_process | mRNA modification |
| C | 0003723 | molecular_function | RNA binding |
| C | 0006396 | biological_process | RNA processing |
| C | 0008174 | molecular_function | mRNA methyltransferase activity |
| C | 0016556 | biological_process | mRNA modification |
| E | 0003723 | molecular_function | RNA binding |
| E | 0006396 | biological_process | RNA processing |
| E | 0008174 | molecular_function | mRNA methyltransferase activity |
| E | 0016556 | biological_process | mRNA modification |
| G | 0003723 | molecular_function | RNA binding |
| G | 0006396 | biological_process | RNA processing |
| G | 0008174 | molecular_function | mRNA methyltransferase activity |
| G | 0016556 | biological_process | mRNA modification |
| I | 0003723 | molecular_function | RNA binding |
| I | 0006396 | biological_process | RNA processing |
| I | 0008174 | molecular_function | mRNA methyltransferase activity |
| I | 0016556 | biological_process | mRNA modification |
| K | 0003723 | molecular_function | RNA binding |
| K | 0006396 | biological_process | RNA processing |
| K | 0008174 | molecular_function | mRNA methyltransferase activity |
| K | 0016556 | biological_process | mRNA modification |
| M | 0003723 | molecular_function | RNA binding |
| M | 0006396 | biological_process | RNA processing |
| M | 0008174 | molecular_function | mRNA methyltransferase activity |
| M | 0016556 | biological_process | mRNA modification |
| O | 0003723 | molecular_function | RNA binding |
| O | 0006396 | biological_process | RNA processing |
| O | 0008174 | molecular_function | mRNA methyltransferase activity |
| O | 0016556 | biological_process | mRNA modification |
| Q | 0003723 | molecular_function | RNA binding |
| Q | 0006396 | biological_process | RNA processing |
| Q | 0008174 | molecular_function | mRNA methyltransferase activity |
| Q | 0016556 | biological_process | mRNA modification |
| S | 0003723 | molecular_function | RNA binding |
| S | 0006396 | biological_process | RNA processing |
| S | 0008174 | molecular_function | mRNA methyltransferase activity |
| S | 0016556 | biological_process | mRNA modification |
| V | 0003723 | molecular_function | RNA binding |
| V | 0006396 | biological_process | RNA processing |
| V | 0008174 | molecular_function | mRNA methyltransferase activity |
| V | 0016556 | biological_process | mRNA modification |
| X | 0003723 | molecular_function | RNA binding |
| X | 0006396 | biological_process | RNA processing |
| X | 0008174 | molecular_function | mRNA methyltransferase activity |
| X | 0016556 | biological_process | mRNA modification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS79 |
| A | VAL81 |
| A | GLU129 |
| A | CYS134 |
| A | CYS141 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 1001 |
| Chain | Residue |
| C | CYS141 |
| C | HIS79 |
| C | VAL81 |
| C | GLU129 |
| C | CYS134 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN E 1001 |
| Chain | Residue |
| E | HIS79 |
| E | VAL81 |
| E | GLU129 |
| E | CYS134 |
| E | CYS141 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN G 1001 |
| Chain | Residue |
| G | HIS79 |
| G | VAL81 |
| G | GLU129 |
| G | CYS134 |
| G | CYS141 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN I 1001 |
| Chain | Residue |
| I | HIS79 |
| I | VAL81 |
| I | GLU129 |
| I | CYS134 |
| I | CYS141 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue ZN K 1001 |
| Chain | Residue |
| K | HIS79 |
| K | VAL81 |
| K | GLU129 |
| K | CYS134 |
| K | CYS141 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN M 1001 |
| Chain | Residue |
| M | HIS79 |
| M | VAL81 |
| M | GLU129 |
| M | CYS134 |
| M | CYS141 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue ZN O 1001 |
| Chain | Residue |
| O | HIS79 |
| O | VAL81 |
| O | GLU129 |
| O | CYS134 |
| O | CYS141 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ZN Q 1001 |
| Chain | Residue |
| Q | HIS79 |
| Q | VAL81 |
| Q | GLU129 |
| Q | CYS134 |
| Q | CYS141 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN S 1001 |
| Chain | Residue |
| S | HIS79 |
| S | VAL81 |
| S | GLU129 |
| S | CYS134 |
| S | CYS141 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN V 1001 |
| Chain | Residue |
| V | HIS79 |
| V | VAL81 |
| V | GLU129 |
| V | CYS134 |
| V | CYS141 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN X 1001 |
| Chain | Residue |
| X | HIS79 |
| X | VAL81 |
| X | GLU129 |
| X | CYS134 |
| X | CYS141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: For mRNA-capping enzyme nsP1 activity => ECO:0000269|PubMed:33730549 |
| Chain | Residue | Details |
| A | HIS37 | |
| S | HIS37 | |
| V | HIS37 | |
| X | HIS37 | |
| C | HIS37 | |
| E | HIS37 | |
| G | HIS37 | |
| I | HIS37 | |
| K | HIS37 | |
| M | HIS37 | |
| O | HIS37 | |
| Q | HIS37 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 48 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33730549 |
| Chain | Residue | Details |
| A | HIS79 | |
| E | GLU129 | |
| E | CYS134 | |
| E | CYS141 | |
| G | HIS79 | |
| G | GLU129 | |
| G | CYS134 | |
| G | CYS141 | |
| I | HIS79 | |
| I | GLU129 | |
| I | CYS134 | |
| A | GLU129 | |
| I | CYS141 | |
| K | HIS79 | |
| K | GLU129 | |
| K | CYS134 | |
| K | CYS141 | |
| M | HIS79 | |
| M | GLU129 | |
| M | CYS134 | |
| M | CYS141 | |
| O | HIS79 | |
| A | CYS134 | |
| O | GLU129 | |
| O | CYS134 | |
| O | CYS141 | |
| Q | HIS79 | |
| Q | GLU129 | |
| Q | CYS134 | |
| Q | CYS141 | |
| S | HIS79 | |
| S | GLU129 | |
| S | CYS134 | |
| A | CYS141 | |
| S | CYS141 | |
| V | HIS79 | |
| V | GLU129 | |
| V | CYS134 | |
| V | CYS141 | |
| X | HIS79 | |
| X | GLU129 | |
| X | CYS134 | |
| X | CYS141 | |
| C | HIS79 | |
| C | GLU129 | |
| C | CYS134 | |
| C | CYS141 | |
| E | HIS79 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | SITE: Involved in the phosphoramide link with 7-methyl-GMP => ECO:0000250|UniProtKB:P27282 |
| Chain | Residue | Details |
| A | HIS37 | |
| S | HIS37 | |
| V | HIS37 | |
| X | HIS37 | |
| C | HIS37 | |
| E | HIS37 | |
| G | HIS37 | |
| I | HIS37 | |
| K | HIS37 | |
| M | HIS37 | |
| O | HIS37 | |
| Q | HIS37 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | LIPID: S-palmitoyl cysteine; by host => ECO:0000305|PubMed:30404808 |
| Chain | Residue | Details |
| A | CYS417 | |
| I | CYS419 | |
| K | CYS417 | |
| K | CYS419 | |
| M | CYS417 | |
| M | CYS419 | |
| O | CYS417 | |
| O | CYS419 | |
| Q | CYS417 | |
| Q | CYS419 | |
| S | CYS417 | |
| A | CYS419 | |
| S | CYS419 | |
| V | CYS417 | |
| V | CYS419 | |
| X | CYS417 | |
| X | CYS419 | |
| C | CYS417 | |
| C | CYS419 | |
| E | CYS417 | |
| E | CYS419 | |
| G | CYS417 | |
| G | CYS419 | |
| I | CYS417 |
