Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6YZA

Trypsin inhibitor in complex with bovine trypsin

Functional Information from GO Data
ChainGOidnamespacecontents
A0004175molecular_functionendopeptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006508biological_processproteolysis
A0007586biological_processdigestion
A0008236molecular_functionserine-type peptidase activity
A0046872molecular_functionmetal ion binding
A0097180cellular_componentserine protease inhibitor complex
A0097655molecular_functionserpin family protein binding
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue CA A 301
ChainResidue
AGLU70
AASN72
AVAL75
AGLU80
AHOH407
AHOH470

site_idAC2
Number of Residues9
Detailsbinding site for residue TP5 A 302
ChainResidue
ASER195
AGLY219
AGLY226
ASO4303
AHOH413
AHOH497
AASP189
ASER190
AGLN192

site_idAC3
Number of Residues9
Detailsbinding site for residue SO4 A 303
ChainResidue
AHIS57
AGLN192
AGLY193
ASER195
ATP5302
AHOH401
AHOH448
AHOH517
AHOH544

site_idAC4
Number of Residues9
Detailsbinding site for residue EDO A 304
ChainResidue
AARG66
AILE73
AASN74
AVAL76
AVAL90
AHIS91
APRO92
AHOH455
AHOH470

site_idAC5
Number of Residues5
Detailsbinding site for residue EDO A 305
ChainResidue
AVAL76
AGLU80
APHE82
AHOH456
AHOH473

Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC
ChainResidueDetails
AVAL53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV
ChainResidueDetails
AASP189-VAL200

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Charge relay system
ChainResidueDetails
AHIS57
AASP102
ASER195

site_idSWS_FT_FI2
Number of Residues7
DetailsBINDING:
ChainResidueDetails
AGLU70
AASN72
AVAL75
AGLU80
AASP189
AGLN192
ASER195

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon