Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6YYD

Crystal structure of SAICAR Synthetase (PurC) from Mycobacterium abscessus in complex with inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0004639molecular_functionphosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0006164biological_processpurine nucleotide biosynthetic process
A0006189biological_process'de novo' IMP biosynthetic process
A0016874molecular_functionligase activity
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue Q0H A 301
ChainResidue
AALA12
AARG91
AARG92
ALEU93
AMET95
AGLU200
AASP213
AHOH530
AHOH565
ASER13
AGLY14
AARG17
AGLU18
ALEU19
ALEU27
APHE29
AHIS69

site_idAC2
Number of Residues8
Detailsbinding site for residue SO4 A 302
ChainResidue
AARG103
AGLY108
ASER109
AARG222
AEDO303
AHOH405
AHOH432
AHOH598

site_idAC3
Number of Residues4
Detailsbinding site for residue EDO A 303
ChainResidue
AASP196
ASER220
ASO4302
AHOH416

Functional Information from PROSITE/UniProt
site_idPS01057
Number of Residues15
DetailsSAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. MLPVEcVARgylTGS
ChainResidueDetails
AMET95-SER109

site_idPS01058
Number of Residues9
DetailsSAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. LADtKFEFG
ChainResidueDetails
ALEU194-GLY202

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon