Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6YY0

bovine ATP synthase F1-peripheral stalk domain, state 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005754	cellular_component	mitochondrial proton-transporting ATP synthase, catalytic core
A	0005886	cellular_component	plasma membrane
A	0006754	biological_process	ATP biosynthetic process
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0032559	molecular_function	adenyl ribonucleotide binding
A	0043531	molecular_function	ADP binding
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
A	0046034	biological_process	ATP metabolic process
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
b	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
b	0015078	molecular_function	proton transmembrane transporter activity
b	0015986	biological_process	proton motive force-driven ATP synthesis
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005754	cellular_component	mitochondrial proton-transporting ATP synthase, catalytic core
B	0005886	cellular_component	plasma membrane
B	0006754	biological_process	ATP biosynthetic process
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0032559	molecular_function	adenyl ribonucleotide binding
B	0043531	molecular_function	ADP binding
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
B	0046034	biological_process	ATP metabolic process
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005754	cellular_component	mitochondrial proton-transporting ATP synthase, catalytic core
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0032559	molecular_function	adenyl ribonucleotide binding
C	0043531	molecular_function	ADP binding
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
C	0046034	biological_process	ATP metabolic process
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
d	0000274	cellular_component	mitochondrial proton-transporting ATP synthase, stator stalk
d	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
d	0005739	cellular_component	mitochondrion
d	0005743	cellular_component	mitochondrial inner membrane
d	0015078	molecular_function	proton transmembrane transporter activity
d	0015986	biological_process	proton motive force-driven ATP synthesis
d	0045259	cellular_component	proton-transporting ATP synthase complex
d	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
d	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
d	1902600	biological_process	proton transmembrane transport
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
D	0006754	biological_process	ATP biosynthetic process
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0016887	molecular_function	ATP hydrolysis activity
D	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
E	0006754	biological_process	ATP biosynthetic process
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0016887	molecular_function	ATP hydrolysis activity
E	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
F	0006754	biological_process	ATP biosynthetic process
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0016887	molecular_function	ATP hydrolysis activity
F	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0000275	cellular_component	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
G	0005515	molecular_function	protein binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006754	biological_process	ATP biosynthetic process
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0045259	cellular_component	proton-transporting ATP synthase complex
G	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
h	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
h	0015078	molecular_function	proton transmembrane transporter activity
h	0015986	biological_process	proton motive force-driven ATP synthesis
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	0000275	cellular_component	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0006754	biological_process	ATP biosynthetic process
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0005739	cellular_component	mitochondrion
J	0032780	biological_process	negative regulation of ATP-dependent activity
J	0042030	molecular_function	ATPase inhibitor activity
S	0015986	biological_process	proton motive force-driven ATP synthesis
S	0016020	cellular_component	membrane
S	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue ATP A 600

Chain	Residue
A	GLN172
A	GLN430
A	GLY431
A	GLN432
A	MG601
A	HOH701
A	HOH702
A	HOH703
D	ASP363
D	TYR372
A	THR173
A	GLY174
A	LYS175
A	THR176
A	SER177
A	PHE357
A	ARG362
A	PRO363

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 601

Chain	Residue
A	THR176
A	ATP600
A	HOH701
A	HOH702
A	HOH703

site_id	AC3
Number of Residues	16
Details	binding site for residue ATP B 600

Chain	Residue
B	GLN172
B	THR173
B	GLY174
B	LYS175
B	THR176
B	SER177
B	GLU328
B	PHE357
B	ARG362
B	GLN430
B	GLY431
B	GLN432
B	MG601
B	HOH701
E	ARG360
E	ASP363

site_id	AC4
Number of Residues	5
Details	binding site for residue MG B 601

Chain	Residue
B	THR176
B	ATP600
B	HOH701
B	HOH702
B	HOH703

site_id	AC5
Number of Residues	17
Details	binding site for residue ATP C 600

Chain	Residue
C	GLN172
C	THR173
C	GLY174
C	LYS175
C	THR176
C	SER177
C	GLU328
C	PHE357
C	GLN430
C	GLY431
C	GLN432
C	MG601
C	HOH701
C	HOH702
F	SER359
F	MET362
F	TYR372

site_id	AC6
Number of Residues	5
Details	binding site for residue MG C 601

Chain	Residue
C	THR176
C	ATP600
C	HOH701
C	HOH702
C	HOH703

site_id	AC7
Number of Residues	13
Details	binding site for residue ADP D 600

Chain	Residue
C	ARG373
D	ALA162
D	GLY163
D	GLY165
D	LYS166
D	THR167
D	VAL168
D	TYR349
D	PHE422
D	ALA425
D	MG601
D	HOH701
D	HOH704

site_id	AC8
Number of Residues	8
Details	binding site for residue MG D 601

Chain	Residue
D	THR167
D	ARG193
D	GLU196
D	ADP600
D	HOH701
D	HOH702
D	HOH703
D	HOH704

site_id	AC9
Number of Residues	9
Details	binding site for residue ADP E 600

Chain	Residue
E	GLY163
E	VAL164
E	GLY165
E	LYS166
E	THR167
E	VAL168
E	TYR349
E	PHE422
E	PHE428

site_id	AD1
Number of Residues	14
Details	binding site for residue ADP F 600

Chain	Residue
F	VAL164
F	GLY165
F	LYS166
F	THR167
F	VAL168
F	TYR349
F	PHE422
F	MG601
F	HOH701
F	HOH703
F	HOH704
B	VAL371
B	ARG373
F	GLY163

site_id	AD2
Number of Residues	8
Details	binding site for residue MG F 601

Chain	Residue
F	THR167
F	ARG193
F	GLU196
F	ADP600
F	HOH701
F	HOH702
F	HOH703
F	HOH704

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAVDPLDSTS

Chain	Residue	Details
D	PRO350-SER359
A	PRO363-SER372

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITkEliEiisGAaA

Chain	Residue	Details
G	ILE258-ALA271

site_id	PS00389
Number of Residues	20
Details	ATPASE_DELTA ATP synthase delta (OSCP) subunit signature. LkLevkIDpSImGGMIVRiG

Chain	Residue	Details
S	LEU148-GLY167

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P18859

Chain	Residue	Details
h	LYS9
h	LYS14
h	LYS73
S	LYS50
S	LYS153
C	GLN430

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P97450

Chain	Residue	Details
h	LYS47
d	LYS47
d	LYS62
d	LYS71

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250\|UniProtKB:P97450

Chain	Residue	Details
h	LYS52
E	LYS476
F	LYS78
F	LYS115
F	LYS213
F	LYS218
F	LYS476
h	LYS67
d	LYS94
d	LYS143
d	LYS148
E	LYS78
E	LYS115
E	LYS213
E	LYS218

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P21571

Chain	Residue	Details
h	SER76
C	SER22
C	SER123
C	SER141
S	LYS169
E	LYS152
E	LYS380
F	LYS152
F	LYS380
B	SER123
B	SER141
C	SER10

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P36542

Chain	Residue	Details
G	SER121
E	THR266
F	THR266

site_id	SWS_FT_FI6
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P06576

Chain	Residue	Details
D	SER369
E	SER369
F	SER369

site_id	SWS_FT_FI7
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P10719

Chain	Residue	Details
D	SER387
B	LYS498
C	LYS80
C	LYS83
C	LYS89
C	LYS197
C	LYS498
E	SER387
F	SER387
A	LYS197
A	LYS498
B	LYS80
B	LYS83
B	LYS89
B	LYS197

site_id	SWS_FT_FI8
Number of Residues	6
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P56480

Chain	Residue	Details
D	LYS434
D	LYS439
E	LYS434
E	LYS439
F	LYS434
F	LYS439

site_id	SWS_FT_FI9
Number of Residues	3
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250

Chain	Residue	Details
D	SER60
A	LYS488
A	LYS496
B	LYS118
B	LYS124
B	LYS187
B	LYS196
B	LYS218
B	LYS262
B	LYS384
B	LYS455
E	SER60
B	LYS463
B	LYS488
B	LYS496
C	LYS118
C	LYS124
C	LYS187
C	LYS196
C	LYS218
C	LYS262
C	LYS384
F	SER60
C	LYS455
C	LYS463
C	LYS488
C	LYS496
A	LYS196
A	LYS218
A	LYS262
A	LYS384
A	LYS455
A	LYS463

site_id	SWS_FT_FI10
Number of Residues	3
Details	MOD_RES: Omega-N-methylarginine => ECO:0000250\|UniProtKB:Q03265

Chain	Residue	Details
A	ARG161
B	ARG161
C	ARG161

site_id	SWS_FT_FI11
Number of Residues	3
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P25705

Chain	Residue	Details
A	LYS391
B	LYS391
C	LYS391

site_id	SWS_FT_FI12
Number of Residues	3
Details	CARBOHYD: O-linked (GlcNAc) serine; alternate => ECO:0000250

Chain	Residue	Details
A	SER33
B	SER33
C	SER33

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	3
Details	M-CSA 178

Chain	Residue	Details
D	LYS166	electrostatic stabiliser
D	GLU192	electrostatic stabiliser
D	ARG193	electrostatic stabiliser

site_id	MCSA2
Number of Residues	3
Details	M-CSA 178

Chain	Residue	Details
E	LYS166	electrostatic stabiliser
E	GLU192	electrostatic stabiliser
E	ARG193	electrostatic stabiliser

site_id	MCSA3
Number of Residues	3
Details	M-CSA 178

Chain	Residue	Details
F	LYS166	electrostatic stabiliser
F	GLU192	electrostatic stabiliser
F	ARG193	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)