6YXU

Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core - State I, primary channel engaged

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0046983	molecular_function	protein dimerization activity
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0046983	molecular_function	protein dimerization activity
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0006351	biological_process	DNA-templated transcription
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0032549	molecular_function	ribonucleoside binding
C	0034062	molecular_function	5'-3' RNA polymerase activity
C	0046677	biological_process	response to antibiotic
D	0000287	molecular_function	magnesium ion binding
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0003677	molecular_function	DNA binding
D	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
D	0006351	biological_process	DNA-templated transcription
D	0008270	molecular_function	zinc ion binding
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0034062	molecular_function	5'-3' RNA polymerase activity
D	0046872	molecular_function	metal ion binding
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0034062	molecular_function	5'-3' RNA polymerase activity
H	0000166	molecular_function	nucleotide binding
H	0000725	biological_process	recombinational repair
H	0003677	molecular_function	DNA binding
H	0003678	molecular_function	DNA helicase activity
H	0004386	molecular_function	helicase activity
H	0005524	molecular_function	ATP binding
H	0005829	cellular_component	cytosol
H	0016787	molecular_function	hydrolase activity
H	0032508	biological_process	DNA duplex unwinding
H	0033202	cellular_component	DNA helicase complex
H	0043138	molecular_function	3'-5' DNA helicase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN D 2001

Chain	Residue
D	CYS890
D	ARG962
D	CYS967
D	CYS974
D	CYS977

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN D 2002

Chain	Residue
D	CYS60
D	CYS62
D	CYS75
D	CYS78

---

site_id	AC3
Number of Residues	3
Details	binding site for residue MG D 2003

Chain	Residue
D	ASP535
D	ASP537
D	ASP539

---

Functional Information from PROSITE/UniProt

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKLAGrHGNKGV

Chain	Residue	Details
C	GLY873-VAL885

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01322

Chain	Residue	Details
D	CYS60
D	CYS974
D	CYS977
D	CYS62
D	CYS75
D	CYS78
D	ASP535
D	ASP537
D	ASP539
D	CYS890
D	CYS967

---