6YW9
Arabidopsis aspartate transcarbamoylase mutant F161A complex with PALA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| C | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue PAL A 401 |
| Chain | Residue |
| A | SER134 |
| A | GLN312 |
| A | LEU350 |
| A | HOH557 |
| A | HOH567 |
| B | SER163 |
| B | LYS166 |
| A | THR135 |
| A | ARG136 |
| A | THR137 |
| A | ARG187 |
| A | HIS215 |
| A | GLN218 |
| A | ARG248 |
| A | ARG310 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ASN246 |
| A | ARG315 |
| A | PHE316 |
| A | ARG319 |
| A | LEU322 |
| A | HOH579 |
| A | HOH641 |
| B | ALA362 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue PAL B 401 |
| Chain | Residue |
| B | SER134 |
| B | THR135 |
| B | ARG136 |
| B | THR137 |
| B | ARG187 |
| B | HIS215 |
| B | GLN218 |
| B | ARG248 |
| B | ARG310 |
| B | GLN312 |
| B | LEU350 |
| B | HOH579 |
| B | HOH614 |
| C | SER163 |
| C | LYS166 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue PAL C 401 |
| Chain | Residue |
| A | SER163 |
| A | LYS166 |
| C | SER134 |
| C | THR135 |
| C | ARG136 |
| C | THR137 |
| C | ARG187 |
| C | HIS215 |
| C | GLN218 |
| C | ARG248 |
| C | ARG310 |
| C | GLN312 |
| C | LEU350 |
| C | HOH565 |
| C | HOH592 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FyEpSTRT |
| Chain | Residue | Details |
| A | PHE130-THR137 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33574254 |
| Chain | Residue | Details |
| A | ARG136 | |
| B | HIS215 | |
| B | ARG248 | |
| B | ARG310 | |
| C | ARG136 | |
| C | THR137 | |
| C | ARG187 | |
| C | HIS215 | |
| C | ARG248 | |
| C | ARG310 | |
| A | THR137 | |
| A | ARG187 | |
| A | HIS215 | |
| A | ARG248 | |
| A | ARG310 | |
| B | ARG136 | |
| B | THR137 | |
| B | ARG187 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P0A786 |
| Chain | Residue | Details |
| A | LYS166 | |
| C | GLN218 | |
| C | LEU350 | |
| C | PRO351 | |
| A | GLN218 | |
| A | LEU350 | |
| A | PRO351 | |
| B | LYS166 | |
| B | GLN218 | |
| B | LEU350 | |
| B | PRO351 | |
| C | LYS166 |
