6YVR
Crystal structure of the neurotensin receptor 1 in complex with the peptide full agonist NTS8-13
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0004930 | molecular_function | G protein-coupled receptor activity |
| AAA | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| AAA | 0016020 | cellular_component | membrane |
| AAA | 0016492 | molecular_function | G protein-coupled neurotensin receptor activity |
| BBB | 0004930 | molecular_function | G protein-coupled receptor activity |
| BBB | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| BBB | 0016020 | cellular_component | membrane |
| BBB | 0016492 | molecular_function | G protein-coupled neurotensin receptor activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=1 |
| Chain | Residue | Details |
| AAA | ALA69-LEU89 | |
| BBB | ALA69-LEU89 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 158 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:24453215 |
| Chain | Residue | Details |
| AAA | ALA90-ASP103 | |
| AAA | GLU166-ARG185 | |
| AAA | ALA261-VAL326 | |
| BBB | ALA90-ASP103 | |
| BBB | GLU166-ARG185 | |
| BBB | ALA261-VAL326 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 38 |
| Details | TRANSMEM: Helical; Name=2 |
| Chain | Residue | Details |
| AAA | TYR104-VAL123 | |
| BBB | TYR104-VAL123 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 128 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:24453215 |
| Chain | Residue | Details |
| AAA | ASP124-LYS143 | |
| AAA | THR207-ARG235 | |
| AAA | TYR349-PRO366 | |
| BBB | ASP124-LYS143 | |
| BBB | THR207-ARG235 | |
| BBB | TYR349-PRO366 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=3 |
| Chain | Residue | Details |
| AAA | GLY144-VAL165 | |
| BBB | GLY144-VAL165 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=4 |
| Chain | Residue | Details |
| AAA | THR186-PHE206 | |
| BBB | THR186-PHE206 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 48 |
| Details | TRANSMEM: Helical; Name=5 |
| Chain | Residue | Details |
| AAA | VAL236-ALA260 | |
| BBB | VAL236-ALA260 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=6 |
| Chain | Residue | Details |
| AAA | ARG327-HIS348 | |
| BBB | ARG327-HIS348 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=7 |
| Chain | Residue | Details |
| AAA | ILE367-GLU387 | |
| BBB | ILE367-GLU387 |
