6YVL
Human OMPD-domain of UMPS in complex with the substrate OMP at 1.25 Angstroms resolution, 1.42 MGy exposure
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue OMP A 501 |
| Chain | Residue |
| A | SER257 |
| A | ASN341 |
| A | MET371 |
| A | SER372 |
| A | PRO417 |
| A | GLN430 |
| A | TYR432 |
| A | GLY450 |
| A | ARG451 |
| A | U502 |
| A | HOH630 |
| A | ASP259 |
| A | HOH638 |
| A | HOH675 |
| A | HOH767 |
| A | LYS281 |
| A | HIS283 |
| A | ASP312 |
| A | ALY314 |
| A | ASP317 |
| A | ILE318 |
| A | THR321 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue U A 502 |
| Chain | Residue |
| A | SER257 |
| A | ASP259 |
| A | LYS281 |
| A | HIS283 |
| A | ASP312 |
| A | ALY314 |
| A | ASP317 |
| A | ILE318 |
| A | THR321 |
| A | MET371 |
| A | SER372 |
| A | PRO417 |
| A | GLN430 |
| A | TYR432 |
| A | GLY450 |
| A | ARG451 |
| A | OMP501 |
| A | HOH630 |
| A | HOH638 |
| A | HOH675 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ARG235 |
| A | LYS468 |
| A | HOH609 |
| A | HOH912 |
| A | HOH920 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | THR374 |
| A | GLY429 |
| A | HOH619 |
| A | HOH624 |
| A | HOH639 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | ARG235 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | ASN433 |
| A | ARG442 |
| A | HOH604 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 507 |
| Chain | Residue |
| A | GLY380 |
| A | ARG384 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 508 |
| Chain | Residue |
| A | SER348 |
| A | LYS352 |
| A | HIS393 |
| A | HOH634 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 509 |
| Chain | Residue |
| A | ARG388 |
| A | HOH643 |
| A | HOH660 |
| A | HOH733 |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IFeDrKfaDIGnTV |
| Chain | Residue | Details |
| A | ILE309-VAL322 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"For OMPdecase activity","evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QCD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QCD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QCH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QCL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
