Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6YVB

Arabidopsis aspartate transcarbamoylase complex with carbamoyl phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004070	molecular_function	aspartate carbamoyltransferase activity
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006520	biological_process	amino acid metabolic process
A	0016597	molecular_function	amino acid binding
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0004070	molecular_function	aspartate carbamoyltransferase activity
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006520	biological_process	amino acid metabolic process
B	0016597	molecular_function	amino acid binding
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0004070	molecular_function	aspartate carbamoyltransferase activity
C	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
C	0006520	biological_process	amino acid metabolic process
C	0016597	molecular_function	amino acid binding
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
D	0004070	molecular_function	aspartate carbamoyltransferase activity
D	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
D	0006520	biological_process	amino acid metabolic process
D	0016597	molecular_function	amino acid binding
D	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
E	0004070	molecular_function	aspartate carbamoyltransferase activity
E	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
E	0006520	biological_process	amino acid metabolic process
E	0016597	molecular_function	amino acid binding
E	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
F	0004070	molecular_function	aspartate carbamoyltransferase activity
F	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
F	0006520	biological_process	amino acid metabolic process
F	0016597	molecular_function	amino acid binding
F	0016743	molecular_function	carboxyl- or carbamoyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue CP A 401

Chain	Residue
A	SER134
A	GOL402
C	SER163
C	HOH501
A	THR135
A	ARG136
A	THR137
A	ARG187
A	HIS215
A	GLN218
A	PRO349
A	LEU350

site_id	AC2
Number of Residues	11
Details	binding site for residue GOL A 402

Chain	Residue
A	HIS215
A	GLN218
A	ARG248
A	THR249
A	PRO349
A	LEU350
A	CP401
A	HOH514
A	HOH604
A	HOH632
A	HOH680

site_id	AC3
Number of Residues	6
Details	binding site for residue GOL A 403

Chain	Residue
A	SER99
A	GLN227
A	LYS232
A	LEU233
A	ASP234
A	HOH539

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 404

Chain	Residue
A	GLU83
A	ASP94
A	GLU96
A	MET97
A	HOH724
C	LYS91

site_id	AC5
Number of Residues	3
Details	binding site for residue GOL A 405

Chain	Residue
A	ARG106
A	GLN227
A	HOH519

site_id	AC6
Number of Residues	8
Details	binding site for residue GOL A 406

Chain	Residue
A	ALA245
A	ASN246
A	LYS276
A	HOH510
A	HOH572
E	ILE272
E	ARG315
E	PHE316

site_id	AC7
Number of Residues	5
Details	binding site for residue ACT A 407

Chain	Residue
A	GLU318
A	LEU320
A	ASP321
E	LYS91
E	HOH1214

site_id	AC8
Number of Residues	5
Details	binding site for residue ACT A 408

Chain	Residue
A	GLY328
A	LYS329
A	PHE330
A	ILE331
A	ASP333

site_id	AC9
Number of Residues	12
Details	binding site for residue CP B 401

Chain	Residue
A	SER163
B	SER134
B	THR135
B	ARG136
B	THR137
B	ARG187
B	HIS215
B	GLN218
B	PRO349
B	LEU350
B	ACT407
B	HOH582

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL B 402

Chain	Residue
B	ARG95
B	SER99
B	GLN227
B	LEU233
B	ASP234
B	HOH519
B	HOH534

site_id	AD2
Number of Residues	8
Details	binding site for residue GOL B 403

Chain	Residue
A	GLY123
B	ILE111
B	GLU112
B	SER114
B	SER116
B	GLN117
B	SER118
B	ARG147

site_id	AD3
Number of Residues	7
Details	binding site for residue GOL B 404

Chain	Residue
B	ARG310
B	ILE311
B	PHE330
B	ILE331
B	ASP354
B	GLU355
B	HOH561

site_id	AD4
Number of Residues	5
Details	binding site for residue ACT B 405

Chain	Residue
B	GLY328
B	LYS329
B	PHE330
B	ILE331
B	ASP333

site_id	AD5
Number of Residues	7
Details	binding site for residue GOL B 406

Chain	Residue
B	HOH532
B	HOH554
F	GLU318
B	GLY90
B	LYS91
B	GLU214
B	SER252

site_id	AD6
Number of Residues	3
Details	binding site for residue ACT B 407

Chain	Residue
B	THR249
B	LEU350
B	CP401

site_id	AD7
Number of Residues	12
Details	binding site for residue CP C 401

Chain	Residue
B	SER163
C	SER134
C	THR135
C	ARG136
C	THR137
C	ARG187
C	HIS215
C	GLN218
C	PRO349
C	LEU350
C	HOH605
C	HOH631

site_id	AD8
Number of Residues	10
Details	binding site for residue GOL C 402

Chain	Residue
A	LYS91
A	TYR255
A	LYS259
A	HOH557
C	GLU83
C	GLN92
C	ASP94
C	HOH535
C	HOH566
C	HOH593

site_id	AD9
Number of Residues	8
Details	binding site for residue GOL C 403

Chain	Residue
C	GLY90
C	LYS91
C	GLU214
C	SER252
C	TYR255
C	HOH687
D	GLU318
D	HOH623

site_id	AE1
Number of Residues	4
Details	binding site for residue ACT C 404

Chain	Residue
C	GLN227
C	LEU233
C	ASP234
C	HOH618

site_id	AE2
Number of Residues	5
Details	binding site for residue ACT C 405

Chain	Residue
C	GLY328
C	LYS329
C	PHE330
C	ILE331
C	ASP333

site_id	AE3
Number of Residues	2
Details	binding site for residue ACT C 406

Chain	Residue
C	HOH520
D	HOH623

site_id	AE4
Number of Residues	12
Details	binding site for residue CP D 401

Chain	Residue
D	SER134
D	THR135
D	ARG136
D	THR137
D	ARG187
D	HIS215
D	GLN218
D	PRO349
D	LEU350
D	HOH564
E	SER163
E	HOH1201

site_id	AE5
Number of Residues	7
Details	binding site for residue GOL D 402

Chain	Residue
C	GLU318
D	GLY90
D	LYS91
D	GLU214
D	SER252
D	HOH598
D	HOH612

site_id	AE6
Number of Residues	5
Details	binding site for residue ACT D 403

Chain	Residue
D	MET297
D	GLY328
D	LYS329
D	ILE331
D	ASP333

site_id	AE7
Number of Residues	9
Details	binding site for residue GOL E 1101

Chain	Residue
A	ILE272
A	ARG315
A	PHE316
A	GLU318
E	ALA245
E	ASN246
E	ARG251
E	LYS276
E	HOH1300

site_id	AE8
Number of Residues	11
Details	binding site for residue CP E 1102

Chain	Residue
E	SER134
E	THR135
E	ARG136
E	THR137
E	ARG187
E	HIS215
E	GLN218
E	PRO349
E	LEU350
E	HOH1364
F	SER163

site_id	AE9
Number of Residues	7
Details	binding site for residue GOL E 1103

Chain	Residue
A	GLU318
E	GLY90
E	LYS91
E	GLU214
E	ARG251
E	SER252
E	HOH1214

site_id	AF1
Number of Residues	5
Details	binding site for residue GOL E 1104

Chain	Residue
E	ARG95
E	SER99
E	GLN227
E	LEU233
E	ASP234

site_id	AF2
Number of Residues	5
Details	binding site for residue ACT E 1105

Chain	Residue
E	GLY328
E	LYS329
E	PHE330
E	ILE331
E	ASP333

site_id	AF3
Number of Residues	10
Details	binding site for residue CP F 401

Chain	Residue
F	SER134
F	THR135
F	ARG136
F	THR137
F	ARG187
F	HIS215
F	GLN218
F	PRO349
F	LEU350
F	HOH572

site_id	AF4
Number of Residues	7
Details	binding site for residue GOL F 402

Chain	Residue
F	SER99
F	GLN227
F	LYS232
F	LEU233
F	ASP234
F	HOH575
F	HOH579

site_id	AF5
Number of Residues	6
Details	binding site for residue GOL F 403

Chain	Residue
F	ARG310
F	ILE311
F	PHE330
F	HOH503
F	HOH592
F	HOH595

site_id	AF6
Number of Residues	5
Details	binding site for residue ACT F 404

Chain	Residue
F	GLY328
F	LYS329
F	PHE330
F	ILE331
F	ASP333

site_id	AF7
Number of Residues	8
Details	binding site for residue GOL F 405

Chain	Residue
D	GLY123
F	ILE111
F	SER114
F	SER115
F	SER116
F	GLN117
F	SER118
F	ARG147

Functional Information from PROSITE/UniProt

site_id	PS00097
Number of Residues	8
Details	CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FyEpSTRT

Chain	Residue	Details
A	PHE130-THR137

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING: BINDING => ECO:0000269\|PubMed:33574254

Chain	Residue	Details
A	ARG136
B	HIS215
B	ARG248
B	ARG310
C	ARG136
C	THR137
C	ARG187
C	HIS215
C	ARG248
C	ARG310
D	ARG136
A	THR137
D	THR137
D	ARG187
D	HIS215
D	ARG248
D	ARG310
E	ARG136
E	THR137
E	ARG187
E	HIS215
E	ARG248
A	ARG187
E	ARG310
F	ARG136
F	THR137
F	ARG187
F	HIS215
F	ARG248
F	ARG310
A	HIS215
A	ARG248
A	ARG310
B	ARG136
B	THR137
B	ARG187

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P0A786

Chain	Residue	Details
A	LYS166
C	GLN218
C	LEU350
C	PRO351
D	LYS166
D	GLN218
D	LEU350
D	PRO351
E	LYS166
E	GLN218
E	LEU350
A	GLN218
E	PRO351
F	LYS166
F	GLN218
F	LEU350
F	PRO351
A	LEU350
A	PRO351
B	LYS166
B	GLN218
B	LEU350
B	PRO351
C	LYS166

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)