6YVB
Arabidopsis aspartate transcarbamoylase complex with carbamoyl phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| C | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| C | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| D | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| D | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0016597 | molecular_function | amino acid binding |
| D | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| E | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| E | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| E | 0006520 | biological_process | amino acid metabolic process |
| E | 0016597 | molecular_function | amino acid binding |
| E | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| F | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| F | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| F | 0006520 | biological_process | amino acid metabolic process |
| F | 0016597 | molecular_function | amino acid binding |
| F | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue CP A 401 |
| Chain | Residue |
| A | SER134 |
| A | GOL402 |
| C | SER163 |
| C | HOH501 |
| A | THR135 |
| A | ARG136 |
| A | THR137 |
| A | ARG187 |
| A | HIS215 |
| A | GLN218 |
| A | PRO349 |
| A | LEU350 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | HIS215 |
| A | GLN218 |
| A | ARG248 |
| A | THR249 |
| A | PRO349 |
| A | LEU350 |
| A | CP401 |
| A | HOH514 |
| A | HOH604 |
| A | HOH632 |
| A | HOH680 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | SER99 |
| A | GLN227 |
| A | LYS232 |
| A | LEU233 |
| A | ASP234 |
| A | HOH539 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | GLU83 |
| A | ASP94 |
| A | GLU96 |
| A | MET97 |
| A | HOH724 |
| C | LYS91 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | ARG106 |
| A | GLN227 |
| A | HOH519 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | ALA245 |
| A | ASN246 |
| A | LYS276 |
| A | HOH510 |
| A | HOH572 |
| E | ILE272 |
| E | ARG315 |
| E | PHE316 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 407 |
| Chain | Residue |
| A | GLU318 |
| A | LEU320 |
| A | ASP321 |
| E | LYS91 |
| E | HOH1214 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 408 |
| Chain | Residue |
| A | GLY328 |
| A | LYS329 |
| A | PHE330 |
| A | ILE331 |
| A | ASP333 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue CP B 401 |
| Chain | Residue |
| A | SER163 |
| B | SER134 |
| B | THR135 |
| B | ARG136 |
| B | THR137 |
| B | ARG187 |
| B | HIS215 |
| B | GLN218 |
| B | PRO349 |
| B | LEU350 |
| B | ACT407 |
| B | HOH582 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | ARG95 |
| B | SER99 |
| B | GLN227 |
| B | LEU233 |
| B | ASP234 |
| B | HOH519 |
| B | HOH534 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| A | GLY123 |
| B | ILE111 |
| B | GLU112 |
| B | SER114 |
| B | SER116 |
| B | GLN117 |
| B | SER118 |
| B | ARG147 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| B | ARG310 |
| B | ILE311 |
| B | PHE330 |
| B | ILE331 |
| B | ASP354 |
| B | GLU355 |
| B | HOH561 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 405 |
| Chain | Residue |
| B | GLY328 |
| B | LYS329 |
| B | PHE330 |
| B | ILE331 |
| B | ASP333 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 406 |
| Chain | Residue |
| B | HOH532 |
| B | HOH554 |
| F | GLU318 |
| B | GLY90 |
| B | LYS91 |
| B | GLU214 |
| B | SER252 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 407 |
| Chain | Residue |
| B | THR249 |
| B | LEU350 |
| B | CP401 |
| site_id | AD7 |
| Number of Residues | 12 |
| Details | binding site for residue CP C 401 |
| Chain | Residue |
| B | SER163 |
| C | SER134 |
| C | THR135 |
| C | ARG136 |
| C | THR137 |
| C | ARG187 |
| C | HIS215 |
| C | GLN218 |
| C | PRO349 |
| C | LEU350 |
| C | HOH605 |
| C | HOH631 |
| site_id | AD8 |
| Number of Residues | 10 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| A | LYS91 |
| A | TYR255 |
| A | LYS259 |
| A | HOH557 |
| C | GLU83 |
| C | GLN92 |
| C | ASP94 |
| C | HOH535 |
| C | HOH566 |
| C | HOH593 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | GLY90 |
| C | LYS91 |
| C | GLU214 |
| C | SER252 |
| C | TYR255 |
| C | HOH687 |
| D | GLU318 |
| D | HOH623 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT C 404 |
| Chain | Residue |
| C | GLN227 |
| C | LEU233 |
| C | ASP234 |
| C | HOH618 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue ACT C 405 |
| Chain | Residue |
| C | GLY328 |
| C | LYS329 |
| C | PHE330 |
| C | ILE331 |
| C | ASP333 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue ACT C 406 |
| Chain | Residue |
| C | HOH520 |
| D | HOH623 |
| site_id | AE4 |
| Number of Residues | 12 |
| Details | binding site for residue CP D 401 |
| Chain | Residue |
| D | SER134 |
| D | THR135 |
| D | ARG136 |
| D | THR137 |
| D | ARG187 |
| D | HIS215 |
| D | GLN218 |
| D | PRO349 |
| D | LEU350 |
| D | HOH564 |
| E | SER163 |
| E | HOH1201 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 402 |
| Chain | Residue |
| C | GLU318 |
| D | GLY90 |
| D | LYS91 |
| D | GLU214 |
| D | SER252 |
| D | HOH598 |
| D | HOH612 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue ACT D 403 |
| Chain | Residue |
| D | MET297 |
| D | GLY328 |
| D | LYS329 |
| D | ILE331 |
| D | ASP333 |
| site_id | AE7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL E 1101 |
| Chain | Residue |
| A | ILE272 |
| A | ARG315 |
| A | PHE316 |
| A | GLU318 |
| E | ALA245 |
| E | ASN246 |
| E | ARG251 |
| E | LYS276 |
| E | HOH1300 |
| site_id | AE8 |
| Number of Residues | 11 |
| Details | binding site for residue CP E 1102 |
| Chain | Residue |
| E | SER134 |
| E | THR135 |
| E | ARG136 |
| E | THR137 |
| E | ARG187 |
| E | HIS215 |
| E | GLN218 |
| E | PRO349 |
| E | LEU350 |
| E | HOH1364 |
| F | SER163 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL E 1103 |
| Chain | Residue |
| A | GLU318 |
| E | GLY90 |
| E | LYS91 |
| E | GLU214 |
| E | ARG251 |
| E | SER252 |
| E | HOH1214 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 1104 |
| Chain | Residue |
| E | ARG95 |
| E | SER99 |
| E | GLN227 |
| E | LEU233 |
| E | ASP234 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue ACT E 1105 |
| Chain | Residue |
| E | GLY328 |
| E | LYS329 |
| E | PHE330 |
| E | ILE331 |
| E | ASP333 |
| site_id | AF3 |
| Number of Residues | 10 |
| Details | binding site for residue CP F 401 |
| Chain | Residue |
| F | SER134 |
| F | THR135 |
| F | ARG136 |
| F | THR137 |
| F | ARG187 |
| F | HIS215 |
| F | GLN218 |
| F | PRO349 |
| F | LEU350 |
| F | HOH572 |
| site_id | AF4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL F 402 |
| Chain | Residue |
| F | SER99 |
| F | GLN227 |
| F | LYS232 |
| F | LEU233 |
| F | ASP234 |
| F | HOH575 |
| F | HOH579 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 403 |
| Chain | Residue |
| F | ARG310 |
| F | ILE311 |
| F | PHE330 |
| F | HOH503 |
| F | HOH592 |
| F | HOH595 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue ACT F 404 |
| Chain | Residue |
| F | GLY328 |
| F | LYS329 |
| F | PHE330 |
| F | ILE331 |
| F | ASP333 |
| site_id | AF7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL F 405 |
| Chain | Residue |
| D | GLY123 |
| F | ILE111 |
| F | SER114 |
| F | SER115 |
| F | SER116 |
| F | GLN117 |
| F | SER118 |
| F | ARG147 |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FyEpSTRT |
| Chain | Residue | Details |
| A | PHE130-THR137 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI3 |
| Number of Residues | 36 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33574254","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 23 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0A786","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
