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6YUP

Heterotetrameric structure of the rBAT-b(0,+)AT1 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005774cellular_componentvacuolar membrane
A0005886cellular_componentplasma membrane
A0005975biological_processcarbohydrate metabolic process
A0006865biological_processamino acid transport
A0010467biological_processgene expression
A0015171molecular_functionamino acid transmembrane transporter activity
A0015174molecular_functionbasic amino acid transmembrane transporter activity
A0015184molecular_functionL-cystine transmembrane transporter activity
A0015802biological_processbasic amino acid transport
A0015810biological_processaspartate transmembrane transport
A0015811biological_processL-cystine transport
A0015813biological_processL-glutamate transmembrane transport
A0016020cellular_componentmembrane
A0016324cellular_componentapical plasma membrane
A0031526cellular_componentbrush border membrane
A0044877molecular_functionprotein-containing complex binding
A0046982molecular_functionprotein heterodimerization activity
A0070062cellular_componentextracellular exosome
A1990822biological_processbasic amino acid transmembrane transport
C0005515molecular_functionprotein binding
C0005774cellular_componentvacuolar membrane
C0005886cellular_componentplasma membrane
C0005975biological_processcarbohydrate metabolic process
C0006865biological_processamino acid transport
C0010467biological_processgene expression
C0015171molecular_functionamino acid transmembrane transporter activity
C0015174molecular_functionbasic amino acid transmembrane transporter activity
C0015184molecular_functionL-cystine transmembrane transporter activity
C0015802biological_processbasic amino acid transport
C0015810biological_processaspartate transmembrane transport
C0015811biological_processL-cystine transport
C0015813biological_processL-glutamate transmembrane transport
C0016020cellular_componentmembrane
C0016324cellular_componentapical plasma membrane
C0031526cellular_componentbrush border membrane
C0044877molecular_functionprotein-containing complex binding
C0046982molecular_functionprotein heterodimerization activity
C0070062cellular_componentextracellular exosome
C1990822biological_processbasic amino acid transmembrane transport
D0003333biological_processamino acid transmembrane transport
D0005515molecular_functionprotein binding
D0005886cellular_componentplasma membrane
D0006865biological_processamino acid transport
D0015171molecular_functionamino acid transmembrane transporter activity
D0015175molecular_functionneutral L-amino acid transmembrane transporter activity
D0015184molecular_functionL-cystine transmembrane transporter activity
D0015297molecular_functionantiporter activity
D0015804biological_processneutral amino acid transport
D0015811biological_processL-cystine transport
D0016020cellular_componentmembrane
D0016324cellular_componentapical plasma membrane
D0022857molecular_functiontransmembrane transporter activity
D0031526cellular_componentbrush border membrane
D0042605molecular_functionpeptide antigen binding
D0046982molecular_functionprotein heterodimerization activity
D0055085biological_processtransmembrane transport
D0065003biological_processprotein-containing complex assembly
D0180009molecular_functionbroad specificity neutral L-amino acid:basic L-amino acid antiporter activity
D1902475biological_processL-alpha-amino acid transmembrane transport
D1990822biological_processbasic amino acid transmembrane transport
E0003333biological_processamino acid transmembrane transport
E0005515molecular_functionprotein binding
E0005886cellular_componentplasma membrane
E0006865biological_processamino acid transport
E0015171molecular_functionamino acid transmembrane transporter activity
E0015175molecular_functionneutral L-amino acid transmembrane transporter activity
E0015184molecular_functionL-cystine transmembrane transporter activity
E0015297molecular_functionantiporter activity
E0015804biological_processneutral amino acid transport
E0015811biological_processL-cystine transport
E0016020cellular_componentmembrane
E0016324cellular_componentapical plasma membrane
E0022857molecular_functiontransmembrane transporter activity
E0031526cellular_componentbrush border membrane
E0042605molecular_functionpeptide antigen binding
E0046982molecular_functionprotein heterodimerization activity
E0055085biological_processtransmembrane transport
E0065003biological_processprotein-containing complex assembly
E0180009molecular_functionbroad specificity neutral L-amino acid:basic L-amino acid antiporter activity
E1902475biological_processL-alpha-amino acid transmembrane transport
E1990822biological_processbasic amino acid transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues292
DetailsTOPO_DOM: Cytoplasmic => ECO:0000305
ChainResidueDetails
DMET1-GLY31
EARG326-PRO351
EGLY392-PRO410
ETYR451-GLU487
DGLU85-TYR110
DASN239-ASN251
DARG326-PRO351
DGLY392-PRO410
DTYR451-GLU487
EMET1-GLY31
EGLU85-TYR110
EASN239-ASN251

site_idSWS_FT_FI2
Number of Residues502
DetailsTRANSMEM: Helical => ECO:0000269|PubMed:32494597, ECO:0007744|PDB:6LI9
ChainResidueDetails
DLEU32-VAL55
DILE371-LEU391
DVAL411-SER431
DTRP435-PHE450
ELEU32-VAL55
EGLY63-ALA84
ELEU111-CYS137
EGLN148-SER169
EVAL170-ILE193
EVAL218-LEU238
ELEU252-TYR274
DGLY63-ALA84
ETRP303-GLY325
EALA352-ASP370
EILE371-LEU391
EVAL411-SER431
ETRP435-PHE450
DLEU111-CYS137
DGLN148-SER169
DVAL170-ILE193
DVAL218-LEU238
DLEU252-TYR274
DTRP303-GLY325
DALA352-ASP370

site_idSWS_FT_FI3
Number of Residues134
DetailsTOPO_DOM: Extracellular => ECO:0000305
ChainResidueDetails
DLEU56-VAL62
ELYS432-THR434
DALA138-PRO147
DSER194-SER217
DPHE275-SER302
DLYS432-THR434
ELEU56-VAL62
EALA138-PRO147
ESER194-SER217
EPHE275-SER302

site_idSWS_FT_FI4
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:32494597, ECO:0007744|PDB:6LI9
ChainResidueDetails
DILE43
DASP233
EILE43
EASP233
CASN214
CPHE318
CLEU319
CGLU321

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P82252
ChainResidueDetails
DSER18
ESER18

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q64319
ChainResidueDetails
ASER10
CSER10

site_idSWS_FT_FI7
Number of Residues12
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN214
CASN495
CASN513
CASN575
AASN261
AASN332
AASN495
AASN513
AASN575
CASN214
CASN261
CASN332

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PDB entries from 2024-11-06

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