Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6YTX

Cryo-EM structure of undecameric human CALHM6 in the presence of Ca2+

Functional Information from GO Data
ChainGOidnamespacecontents
A0005261molecular_functionmonoatomic cation channel activity
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0034220biological_processmonoatomic ion transmembrane transport
A0098655biological_processmonoatomic cation transmembrane transport
B0005261molecular_functionmonoatomic cation channel activity
B0005515molecular_functionprotein binding
B0005886cellular_componentplasma membrane
B0034220biological_processmonoatomic ion transmembrane transport
B0098655biological_processmonoatomic cation transmembrane transport
C0005261molecular_functionmonoatomic cation channel activity
C0005515molecular_functionprotein binding
C0005886cellular_componentplasma membrane
C0034220biological_processmonoatomic ion transmembrane transport
C0098655biological_processmonoatomic cation transmembrane transport
D0005261molecular_functionmonoatomic cation channel activity
D0005515molecular_functionprotein binding
D0005886cellular_componentplasma membrane
D0034220biological_processmonoatomic ion transmembrane transport
D0098655biological_processmonoatomic cation transmembrane transport
E0005261molecular_functionmonoatomic cation channel activity
E0005515molecular_functionprotein binding
E0005886cellular_componentplasma membrane
E0034220biological_processmonoatomic ion transmembrane transport
E0098655biological_processmonoatomic cation transmembrane transport
F0005261molecular_functionmonoatomic cation channel activity
F0005515molecular_functionprotein binding
F0005886cellular_componentplasma membrane
F0034220biological_processmonoatomic ion transmembrane transport
F0098655biological_processmonoatomic cation transmembrane transport
G0005261molecular_functionmonoatomic cation channel activity
G0005515molecular_functionprotein binding
G0005886cellular_componentplasma membrane
G0034220biological_processmonoatomic ion transmembrane transport
G0098655biological_processmonoatomic cation transmembrane transport
H0005261molecular_functionmonoatomic cation channel activity
H0005515molecular_functionprotein binding
H0005886cellular_componentplasma membrane
H0034220biological_processmonoatomic ion transmembrane transport
H0098655biological_processmonoatomic cation transmembrane transport
I0005261molecular_functionmonoatomic cation channel activity
I0005515molecular_functionprotein binding
I0005886cellular_componentplasma membrane
I0034220biological_processmonoatomic ion transmembrane transport
I0098655biological_processmonoatomic cation transmembrane transport
J0005261molecular_functionmonoatomic cation channel activity
J0005515molecular_functionprotein binding
J0005886cellular_componentplasma membrane
J0034220biological_processmonoatomic ion transmembrane transport
J0098655biological_processmonoatomic cation transmembrane transport
K0005261molecular_functionmonoatomic cation channel activity
K0005515molecular_functionprotein binding
K0005886cellular_componentplasma membrane
K0034220biological_processmonoatomic ion transmembrane transport
K0098655biological_processmonoatomic cation transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1925
DetailsTOPO_DOM: Cytoplasmic => ECO:0000305
ChainResidueDetails
AMET1-GLY21
DMET1-GLY21
DVAL69-ILE102
DTHR193-LEU315
EMET1-GLY21
EVAL69-ILE102
ETHR193-LEU315
FMET1-GLY21
FVAL69-ILE102
FTHR193-LEU315
GMET1-GLY21
AVAL69-ILE102
GVAL69-ILE102
GTHR193-LEU315
HMET1-GLY21
HVAL69-ILE102
HTHR193-LEU315
IMET1-GLY21
IVAL69-ILE102
ITHR193-LEU315
JMET1-GLY21
JVAL69-ILE102
ATHR193-LEU315
JTHR193-LEU315
KMET1-GLY21
KVAL69-ILE102
KTHR193-LEU315
BMET1-GLY21
BVAL69-ILE102
BTHR193-LEU315
CMET1-GLY21
CVAL69-ILE102
CTHR193-LEU315

site_idSWS_FT_FI2
Number of Residues165
DetailsTRANSMEM: Helical; Name=S1 => ECO:0000269|PubMed:32374262, ECO:0007744|PDB:6YTV
ChainResidueDetails
ALEU22-VAL37
JLEU22-VAL37
KLEU22-VAL37
BLEU22-VAL37
CLEU22-VAL37
DLEU22-VAL37
ELEU22-VAL37
FLEU22-VAL37
GLEU22-VAL37
HLEU22-VAL37
ILEU22-VAL37

site_idSWS_FT_FI3
Number of Residues539
DetailsTOPO_DOM: Extracellular => ECO:0000305
ChainResidueDetails
AALA38-ALA46
EALA128-ASP169
FALA38-ALA46
FALA128-ASP169
GALA38-ALA46
GALA128-ASP169
HALA38-ALA46
HALA128-ASP169
IALA38-ALA46
IALA128-ASP169
JALA38-ALA46
AALA128-ASP169
JALA128-ASP169
KALA38-ALA46
KALA128-ASP169
BALA38-ALA46
BALA128-ASP169
CALA38-ALA46
CALA128-ASP169
DALA38-ALA46
DALA128-ASP169
EALA38-ALA46

site_idSWS_FT_FI4
Number of Residues231
DetailsTRANSMEM: Helical; Name=S2 => ECO:0000269|PubMed:32374262, ECO:0007744|PDB:6YTV
ChainResidueDetails
ATRP47-TYR68
JTRP47-TYR68
KTRP47-TYR68
BTRP47-TYR68
CTRP47-TYR68
DTRP47-TYR68
ETRP47-TYR68
FTRP47-TYR68
GTRP47-TYR68
HTRP47-TYR68
ITRP47-TYR68

site_idSWS_FT_FI5
Number of Residues264
DetailsTRANSMEM: Helical; Name=S3 => ECO:0000269|PubMed:32374262, ECO:0007744|PDB:6YTV
ChainResidueDetails
ASER103-ALA127
JSER103-ALA127
KSER103-ALA127
BSER103-ALA127
CSER103-ALA127
DSER103-ALA127
ESER103-ALA127
FSER103-ALA127
GSER103-ALA127
HSER103-ALA127
ISER103-ALA127

site_idSWS_FT_FI6
Number of Residues242
DetailsTRANSMEM: Helical; Name=S4 => ECO:0000269|PubMed:32374262, ECO:0007744|PDB:6YTV
ChainResidueDetails
ALEU170-PHE192
JLEU170-PHE192
KLEU170-PHE192
BLEU170-PHE192
CLEU170-PHE192
DLEU170-PHE192
ELEU170-PHE192
FLEU170-PHE192
GLEU170-PHE192
HLEU170-PHE192
ILEU170-PHE192

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon