Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6YSO

Crystal structure of the (SR) Ca2+-ATPase solved by vanadium SAD phasing

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005215	molecular_function	transporter activity
A	0005388	molecular_function	P-type calcium transporter activity
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0006811	biological_process	monoatomic ion transport
A	0006816	biological_process	calcium ion transport
A	0016020	cellular_component	membrane
A	0016529	cellular_component	sarcoplasmic reticulum
A	0016887	molecular_function	ATP hydrolysis activity
A	0031448	biological_process	positive regulation of fast-twitch skeletal muscle fiber contraction
A	0033017	cellular_component	sarcoplasmic reticulum membrane
A	0046872	molecular_function	metal ion binding
A	0070588	biological_process	calcium ion transmembrane transport
A	0106134	biological_process	positive regulation of cardiac muscle cell contraction
A	1901896	biological_process	positive regulation of ATPase-coupled calcium transmembrane transporter activity
A	1902082	biological_process	positive regulation of calcium ion import into sarcoplasmic reticulum
A	1990036	biological_process	calcium ion import into sarcoplasmic reticulum
B	0000166	molecular_function	nucleotide binding
B	0005215	molecular_function	transporter activity
B	0005388	molecular_function	P-type calcium transporter activity
B	0005509	molecular_function	calcium ion binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0006811	biological_process	monoatomic ion transport
B	0006816	biological_process	calcium ion transport
B	0016020	cellular_component	membrane
B	0016529	cellular_component	sarcoplasmic reticulum
B	0016887	molecular_function	ATP hydrolysis activity
B	0031448	biological_process	positive regulation of fast-twitch skeletal muscle fiber contraction
B	0033017	cellular_component	sarcoplasmic reticulum membrane
B	0046872	molecular_function	metal ion binding
B	0070588	biological_process	calcium ion transmembrane transport
B	0106134	biological_process	positive regulation of cardiac muscle cell contraction
B	1901896	biological_process	positive regulation of ATPase-coupled calcium transmembrane transporter activity
B	1902082	biological_process	positive regulation of calcium ion import into sarcoplasmic reticulum
B	1990036	biological_process	calcium ion import into sarcoplasmic reticulum

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue 128 A 1000

Chain	Residue
A	VAL185
A	ALA517
A	ARG560
A	ASN628
A	ARG678
A	MG1004
A	HOH1103
A	SER186
A	ILE188
A	LYS205
A	THR441
A	PHE487
A	MET494
A	LYS515
A	GLY516

site_id	AC2
Number of Residues	13
Details	binding site for residue TG1 A 1001

Chain	Residue
A	GLU255
A	PHE256
A	GLN259
A	LEU260
A	ILE267
A	ALA306
A	ILE761
A	ILE765
A	VAL769
A	LEU828
A	ILE829
A	PHE834
A	TYR837

site_id	AC3
Number of Residues	11
Details	binding site for residue VN4 A 1002

Chain	Residue
A	GLY182
A	ASP351
A	LYS352
A	THR353
A	THR625
A	GLY626
A	LYS684
A	ASN706
A	MG1003
A	HOH1101
A	HOH1102

site_id	AC4
Number of Residues	6
Details	binding site for residue MG A 1003

Chain	Residue
A	ASP351
A	THR353
A	ASP703
A	VN41002
A	HOH1102
A	HOH1104

site_id	AC5
Number of Residues	3
Details	binding site for residue MG A 1004

Chain	Residue
A	ASN628
A	1281000
A	HOH1103

site_id	AC6
Number of Residues	2
Details	binding site for residue CL A 1005

Chain	Residue
A	LYS629
A	ARG678

site_id	AC7
Number of Residues	5
Details	binding site for residue K A 1006

Chain	Residue
A	GLN244
A	LEU711
A	LYS712
A	ALA714
A	GLU732

site_id	AC8
Number of Residues	17
Details	binding site for residue 128 B 2000

Chain	Residue
B	VAL185
B	SER186
B	VAL187
B	ILE188
B	LYS205
B	MET361
B	GLU439
B	THR441
B	PHE487
B	MET494
B	LYS515
B	ALA517
B	ARG560
B	ASN628
B	ARG678
B	MG2004
B	HOH2103

site_id	AC9
Number of Residues	11
Details	binding site for residue TG1 B 2001

Chain	Residue
B	PHE256
B	GLN259
B	LEU260
B	VAL263
B	LEU266
B	ILE267
B	ASN768
B	VAL769
B	LEU828
B	ILE829
B	PHE834

site_id	AD1
Number of Residues	13
Details	binding site for residue VN4 B 2002

Chain	Residue
B	THR181
B	GLY182
B	ASP351
B	LYS352
B	THR353
B	THR625
B	GLY626
B	LYS684
B	ASN706
B	MG2003
B	HOH2101
B	HOH2102
B	HOH2104

site_id	AD2
Number of Residues	6
Details	binding site for residue MG B 2003

Chain	Residue
B	VN42002
B	HOH2102
B	HOH2104
B	ASP351
B	THR353
B	ASP703

site_id	AD3
Number of Residues	3
Details	binding site for residue MG B 2004

Chain	Residue
B	ASN628
B	1282000
B	HOH2103

site_id	AD4
Number of Residues	2
Details	binding site for residue CL B 2005

Chain	Residue
B	LYS629
B	ARG678

site_id	AD5
Number of Residues	6
Details	binding site for residue K B 2006

Chain	Residue
B	GLN244
B	LEU711
B	LYS712
B	ALA714
B	GLY717
B	GLU732

Functional Information from PROSITE/UniProt

site_id	PS00154
Number of Residues	7
Details	ATPASE_E1_E2 E1-E2 ATPases phosphorylation site. DKTGTLT

Chain	Residue	Details
A	ASP351-THR357

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1326
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	84
Details	Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	38
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	34
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	38
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	44
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	38
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	36
Details	Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	40
Details	Region: {"description":"Interaction with PLN","evidences":[{"source":"PubMed","id":"10551848","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23996003","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	22
Details	Region: {"description":"Interaction with PLN","evidences":[{"source":"PubMed","id":"23996003","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	2
Details	Active site: {"description":"4-aspartylphosphate intermediate","evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18075584","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NAB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WPG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XP5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B9B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B9R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FPB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N5K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BEW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5A3Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5A3S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BY4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DQS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UU1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WPG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DQS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B9R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FPB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BEW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BY4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UU1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BY4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C88","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DQS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B9R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UU1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI25
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI26
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UU1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI27
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI28
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FPB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BEW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI29
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI30
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI31
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NAB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI32
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI33
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI34
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3N8G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NAB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI35
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10864315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15192230","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15229613","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26175901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1T5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AR2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NAB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XOU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI36
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q64578","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI37
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q64578","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	3
Details	M-CSA 849

Chain	Residue	Details
A	ASP351	covalent catalysis
A	ASP703	metal ligand
A	ASP707	metal ligand

site_id	MCSA2
Number of Residues	3
Details	M-CSA 849

Chain	Residue	Details
B	ASP351	covalent catalysis
B	ASP703	metal ligand
B	ASP707	metal ligand

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)