Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue HEM A 401 |
| Chain | Residue |
| A | ASP146 |
| A | HIS225 |
| A | THR229 |
| A | SER230 |
| A | ARG243 |
| A | ASN245 |
| A | THR258 |
| A | PHE260 |
| A | MET273 |
| A | LEU274 |
| A | MET277 |
| A | VAL151 |
| A | ILE289 |
| A | HOH557 |
| A | HOH583 |
| A | HOH595 |
| A | HOH622 |
| A | ASP152 |
| A | GLY153 |
| A | THR154 |
| A | GLU155 |
| A | GLN184 |
| A | TYR186 |
| A | ARG207 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 7PE A 402 |
| Chain | Residue |
| A | GLU155 |
| A | ASN156 |
| A | HOH518 |
| A | HOH641 |
| F | ARG48 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue 7PE A 403 |
| Chain | Residue |
| A | GLU171 |
| A | ASP172 |
| A | ARG265 |
| A | HOH507 |
| A | HOH521 |
| A | HOH574 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 404 |
| Chain | Residue |
| A | ASP191 |
| A | HOH502 |
| A | HOH616 |
| D | HOH552 |
| D | HOH569 |
| D | HOH631 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 405 |
| Chain | Residue |
| A | HOH557 |
| A | HOH563 |
| A | HOH622 |
| A | HOH627 |
| A | HOH693 |
| A | HOH714 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 406 |
| Chain | Residue |
| A | GLU144 |
| A | HOH508 |
| A | HOH565 |
| A | HOH649 |
| A | HOH688 |
| site_id | AC7 |
| Number of Residues | 22 |
| Details | binding site for residue HEM B 401 |
| Chain | Residue |
| B | ASP146 |
| B | VAL151 |
| B | ASP152 |
| B | GLY153 |
| B | THR154 |
| B | GLU155 |
| B | GLN184 |
| B | TYR186 |
| B | HIS188 |
| B | ARG207 |
| B | HIS225 |
| B | VAL226 |
| B | THR229 |
| B | SER230 |
| B | ARG243 |
| B | ASN245 |
| B | THR258 |
| B | PHE260 |
| B | LEU274 |
| B | ILE289 |
| B | HOH515 |
| B | HOH549 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue 7PE B 402 |
| Chain | Residue |
| B | GLU199 |
| B | GLU202 |
| B | ARG203 |
| B | ARG208 |
| B | LEU215 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | GLU194 |
| B | GLY195 |
| B | LEU196 |
| F | GLU33 |
| F | ARG73 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue 7PE B 404 |
| Chain | Residue |
| B | TYR141 |
| B | MET147 |
| B | ILE190 |
| B | GLU194 |
| B | HOH532 |
| E | THR120 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| B | ASP189 |
| B | ASP191 |
| F | GLU69 |
| site_id | AD3 |
| Number of Residues | 22 |
| Details | binding site for residue HEM C 401 |
| Chain | Residue |
| C | GLN184 |
| C | TYR186 |
| C | HIS188 |
| C | ARG207 |
| C | HIS225 |
| C | VAL226 |
| C | THR229 |
| C | SER230 |
| C | ARG243 |
| C | ASN245 |
| C | THR258 |
| C | PHE260 |
| C | MET273 |
| C | LEU274 |
| C | HOH550 |
| C | HOH617 |
| C | ASP146 |
| C | VAL151 |
| C | ASP152 |
| C | GLY153 |
| C | THR154 |
| C | GLU155 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| B | GLU310 |
| C | GLU240 |
| C | HOH629 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | GLU310 |
| C | HOH630 |
| C | HOH649 |
| D | GLU240 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 404 |
| Chain | Residue |
| C | HOH564 |
| C | HOH569 |
| C | HOH679 |
| D | HOH546 |
| D | HOH570 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 405 |
| Chain | Residue |
| C | MET210 |
| C | THR211 |
| C | HOH541 |
| E | LYS209 |
| E | HOH539 |
| site_id | AD8 |
| Number of Residues | 22 |
| Details | binding site for residue HEM D 401 |
| Chain | Residue |
| D | ASP146 |
| D | VAL151 |
| D | ASP152 |
| D | GLY153 |
| D | THR154 |
| D | GLU155 |
| D | GLN184 |
| D | TYR186 |
| D | HIS188 |
| D | ARG207 |
| D | HIS225 |
| D | VAL226 |
| D | THR229 |
| D | ARG243 |
| D | ASN245 |
| D | THR258 |
| D | PHE260 |
| D | LEU274 |
| D | MET277 |
| D | ILE289 |
| D | HOH528 |
| D | HOH578 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue 7PE D 402 |
| Chain | Residue |
| D | GLY82 |
| D | GLU171 |
| D | ARG265 |
| D | THR266 |
| D | GLU268 |
| D | HOH521 |
| site_id | AE1 |
| Number of Residues | 22 |
| Details | binding site for residue HEM E 401 |
| Chain | Residue |
| E | ASP146 |
| E | VAL151 |
| E | ASP152 |
| E | GLY153 |
| E | THR154 |
| E | GLU155 |
| E | GLN184 |
| E | TYR186 |
| E | HIS188 |
| E | ARG207 |
| E | HIS225 |
| E | THR229 |
| E | SER230 |
| E | ARG243 |
| E | ASN245 |
| E | THR258 |
| E | PHE260 |
| E | LEU274 |
| E | MET277 |
| E | ILE289 |
| E | HOH569 |
| E | HOH583 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 402 |
| Chain | Residue |
| E | GLU310 |
| E | HOH637 |
| E | HOH670 |
| E | HOH674 |
| F | HOH541 |
| F | HOH545 |
| site_id | AE3 |
| Number of Residues | 25 |
| Details | binding site for residue HEM F 401 |
| Chain | Residue |
| F | ASP146 |
| F | PHE150 |
| F | VAL151 |
| F | ASP152 |
| F | GLY153 |
| F | THR154 |
| F | GLU155 |
| F | GLN184 |
| F | TYR186 |
| F | HIS188 |
| F | ARG207 |
| F | HIS225 |
| F | VAL226 |
| F | THR229 |
| F | SER230 |
| F | ARG243 |
| F | ASN245 |
| F | THR258 |
| F | PHE260 |
| F | MET273 |
| F | LEU274 |
| F | MET277 |
| F | ILE289 |
| F | HOH562 |
| F | HOH604 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue 7PE F 402 |
| Chain | Residue |
| F | ASP217 |
| F | LYS220 |
| F | ALA222 |
| F | ALA227 |
| F | HOH503 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL F 403 |
| Chain | Residue |
| F | SER313 |
| F | ALA314 |
| F | HOH526 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 404 |
| Chain | Residue |
| F | SER30 |
| F | GLY31 |
| F | ARG208 |
| F | SER216 |
| F | VAL219 |
| F | HOH654 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue 7PE F 405 |
| Chain | Residue |
| F | THR99 |
| F | PRO100 |
| F | GLN133 |
| F | ASP134 |
| F | THR297 |
| F | HOH553 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL F 406 |
| Chain | Residue |
| F | THR27 |
| F | ILE28 |
| F | ASP29 |
| F | THR131 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 407 |
| Chain | Residue |
| D | ARG53 |
| F | TYR141 |
| F | PHE142 |
| F | ASP143 |
| F | HOH520 |
| F | HOH609 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue 7PE F 408 |
| Chain | Residue |
| D | THR120 |
| F | TYR141 |
| F | MET147 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue 7PE F 409 |
| Chain | Residue |
| F | LYS185 |
| F | GLU255 |
| F | HOH637 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue 7PE F 410 |
| Chain | Residue |
| E | ARG48 |
| F | GLU155 |
| F | ASN156 |
| F | PRO157 |
| F | HOH541 |
| F | HOH633 |
