6YR2

TetR(D) soaked with Tigecycline P4(1)2(1)2

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000976	molecular_function	transcription cis-regulatory region binding
AAA	0003677	molecular_function	DNA binding
AAA	0003700	molecular_function	DNA-binding transcription factor activity
AAA	0006355	biological_process	regulation of DNA-templated transcription
AAA	0045892	biological_process	negative regulation of DNA-templated transcription
AAA	0046677	biological_process	response to antibiotic
AAA	0046872	molecular_function	metal ion binding
BBB	0000976	molecular_function	transcription cis-regulatory region binding
BBB	0003677	molecular_function	DNA binding
BBB	0003700	molecular_function	DNA-binding transcription factor activity
BBB	0006355	biological_process	regulation of DNA-templated transcription
BBB	0045892	biological_process	negative regulation of DNA-templated transcription
BBB	0046677	biological_process	response to antibiotic
BBB	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS01081
Number of Residues	32
Details	HTH_TETR_1 TetR-type HTH domain signature. GIdglTTrkLaqklgIEqPtLYwHVkNKralL

Chain	Residue	Details
AAA	GLY21-LEU52

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335

Chain	Residue	Details
AAA	THR26-VAL45
BBB	THR26-VAL45

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:8153629, ECO:0007744|PDB:2TRT

Chain	Residue	Details
AAA	HIS100
BBB	HIS64
BBB	ASN82
BBB	HIS100
AAA	ASN82
AAA	HIS64

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