6YOP
Structure of SAMM50 LIR bound to GABARAP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000045 | biological_process | autophagosome assembly |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0000226 | biological_process | microtubule cytoskeleton organization |
| A | 0000421 | cellular_component | autophagosome membrane |
| A | 0000423 | biological_process | mitophagy |
| A | 0005515 | molecular_function | protein binding |
| A | 0005543 | molecular_function | phospholipid binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005764 | cellular_component | lysosome |
| A | 0005776 | cellular_component | autophagosome |
| A | 0005790 | cellular_component | smooth endoplasmic reticulum |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005829 | cellular_component | cytosol |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005874 | cellular_component | microtubule |
| A | 0005875 | cellular_component | microtubule associated complex |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005930 | cellular_component | axoneme |
| A | 0006605 | biological_process | protein targeting |
| A | 0006914 | biological_process | autophagy |
| A | 0006915 | biological_process | apoptotic process |
| A | 0006995 | biological_process | cellular response to nitrogen starvation |
| A | 0007268 | biological_process | chemical synaptic transmission |
| A | 0008017 | molecular_function | microtubule binding |
| A | 0008429 | molecular_function | phosphatidylethanolamine binding |
| A | 0008625 | biological_process | extrinsic apoptotic signaling pathway via death domain receptors |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0015031 | biological_process | protein transport |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0016020 | cellular_component | membrane |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0031625 | molecular_function | ubiquitin protein ligase binding |
| A | 0032436 | biological_process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| A | 0035020 | biological_process | regulation of Rac protein signal transduction |
| A | 0048487 | molecular_function | beta-tubulin binding |
| A | 0050811 | molecular_function | GABA receptor binding |
| A | 0097225 | cellular_component | sperm midpiece |
| A | 0097352 | biological_process | autophagosome maturation |
| A | 0098696 | biological_process | regulation of neurotransmitter receptor localization to postsynaptic specialization membrane |
| A | 0098982 | cellular_component | GABA-ergic synapse |
| A | 1902524 | biological_process | positive regulation of protein K48-linked ubiquitination |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Propeptide: {"description":"Removed in mature form","featureId":"PRO_0000423065","evidences":[{"source":"PubMed","id":"15169837","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Region: {"description":"Interaction with beta-tubulin","evidences":[{"source":"PubMed","id":"9892355","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 81 |
| Details | Region: {"description":"Interaction with GPHN","evidences":[{"source":"UniProtKB","id":"Q9DCD6","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 32 |
| Details | Region: {"description":"Interaction with GABRG2","evidences":[{"source":"PubMed","id":"9892355","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Region: {"description":"Interaction with LIR (LC3 nteracting Region) motif of ATG3","evidences":[{"source":"PubMed","id":"37252361","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8AFI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with LIR (LC3 nteracting Region) motif of ATG3","evidences":[{"source":"PubMed","id":"37252361","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8AFI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by ATG4B","evidences":[{"source":"PubMed","id":"15169837","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"Phosphatidylserine amidated glycine; alternate","evidences":[{"source":"PubMed","id":"33909989","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
