6YNS

CaM-P458 complex (crystal form 2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000922	cellular_component	spindle pole
A	0002027	biological_process	regulation of heart rate
A	0005246	molecular_function	calcium channel regulator activity
A	0005509	molecular_function	calcium ion binding
A	0005513	biological_process	detection of calcium ion
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005813	cellular_component	centrosome
A	0005819	cellular_component	spindle
A	0005829	cellular_component	cytosol
A	0005876	cellular_component	spindle microtubule
A	0005886	cellular_component	plasma membrane
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0008076	cellular_component	voltage-gated potassium channel complex
A	0010856	molecular_function	adenylate cyclase activator activity
A	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
A	0016020	cellular_component	membrane
A	0016240	biological_process	autophagosome membrane docking
A	0019855	molecular_function	calcium channel inhibitor activity
A	0019901	molecular_function	protein kinase binding
A	0021762	biological_process	substantia nigra development
A	0030017	cellular_component	sarcomere
A	0031432	molecular_function	titin binding
A	0031514	cellular_component	motile cilium
A	0031982	cellular_component	vesicle
A	0032465	biological_process	regulation of cytokinesis
A	0032991	cellular_component	protein-containing complex
A	0034704	cellular_component	calcium channel complex
A	0035458	biological_process	cellular response to interferon-beta
A	0043209	cellular_component	myelin sheath
A	0043539	molecular_function	protein serine/threonine kinase activator activity
A	0044305	cellular_component	calyx of Held
A	0044325	molecular_function	transmembrane transporter binding
A	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
A	0046872	molecular_function	metal ion binding
A	0048306	molecular_function	calcium-dependent protein binding
A	0051592	biological_process	response to calcium ion
A	0055117	biological_process	regulation of cardiac muscle contraction
A	0060291	biological_process	long-term synaptic potentiation
A	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
A	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
A	0071346	biological_process	cellular response to type II interferon
A	0072542	molecular_function	protein phosphatase activator activity
A	0097225	cellular_component	sperm midpiece
A	0097720	biological_process	calcineurin-mediated signaling
A	0098901	biological_process	regulation of cardiac muscle cell action potential
A	0099523	cellular_component	presynaptic cytosol
A	0140056	biological_process	organelle localization by membrane tethering
A	0140238	biological_process	presynaptic endocytosis
A	0141110	molecular_function	transporter inhibitor activity
A	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
A	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
A	1902494	cellular_component	catalytic complex
A	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
A	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
B	0000922	cellular_component	spindle pole
B	0002027	biological_process	regulation of heart rate
B	0005246	molecular_function	calcium channel regulator activity
B	0005509	molecular_function	calcium ion binding
B	0005513	biological_process	detection of calcium ion
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005813	cellular_component	centrosome
B	0005819	cellular_component	spindle
B	0005829	cellular_component	cytosol
B	0005876	cellular_component	spindle microtubule
B	0005886	cellular_component	plasma membrane
B	0007186	biological_process	G protein-coupled receptor signaling pathway
B	0008076	cellular_component	voltage-gated potassium channel complex
B	0010856	molecular_function	adenylate cyclase activator activity
B	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B	0016020	cellular_component	membrane
B	0016240	biological_process	autophagosome membrane docking
B	0019855	molecular_function	calcium channel inhibitor activity
B	0019901	molecular_function	protein kinase binding
B	0021762	biological_process	substantia nigra development
B	0030017	cellular_component	sarcomere
B	0031432	molecular_function	titin binding
B	0031514	cellular_component	motile cilium
B	0031982	cellular_component	vesicle
B	0032465	biological_process	regulation of cytokinesis
B	0032991	cellular_component	protein-containing complex
B	0034704	cellular_component	calcium channel complex
B	0035458	biological_process	cellular response to interferon-beta
B	0043209	cellular_component	myelin sheath
B	0043539	molecular_function	protein serine/threonine kinase activator activity
B	0044305	cellular_component	calyx of Held
B	0044325	molecular_function	transmembrane transporter binding
B	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
B	0046872	molecular_function	metal ion binding
B	0048306	molecular_function	calcium-dependent protein binding
B	0051592	biological_process	response to calcium ion
B	0055117	biological_process	regulation of cardiac muscle contraction
B	0060291	biological_process	long-term synaptic potentiation
B	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
B	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
B	0071346	biological_process	cellular response to type II interferon
B	0072542	molecular_function	protein phosphatase activator activity
B	0097225	cellular_component	sperm midpiece
B	0097720	biological_process	calcineurin-mediated signaling
B	0098901	biological_process	regulation of cardiac muscle cell action potential
B	0099523	cellular_component	presynaptic cytosol
B	0140056	biological_process	organelle localization by membrane tethering
B	0140238	biological_process	presynaptic endocytosis
B	0141110	molecular_function	transporter inhibitor activity
B	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
B	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
B	1902494	cellular_component	catalytic complex
B	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
B	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
C	0000922	cellular_component	spindle pole
C	0002027	biological_process	regulation of heart rate
C	0005246	molecular_function	calcium channel regulator activity
C	0005509	molecular_function	calcium ion binding
C	0005513	biological_process	detection of calcium ion
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005813	cellular_component	centrosome
C	0005819	cellular_component	spindle
C	0005829	cellular_component	cytosol
C	0005876	cellular_component	spindle microtubule
C	0005886	cellular_component	plasma membrane
C	0007186	biological_process	G protein-coupled receptor signaling pathway
C	0008076	cellular_component	voltage-gated potassium channel complex
C	0010856	molecular_function	adenylate cyclase activator activity
C	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
C	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
C	0016020	cellular_component	membrane
C	0016240	biological_process	autophagosome membrane docking
C	0019855	molecular_function	calcium channel inhibitor activity
C	0019901	molecular_function	protein kinase binding
C	0021762	biological_process	substantia nigra development
C	0030017	cellular_component	sarcomere
C	0031432	molecular_function	titin binding
C	0031514	cellular_component	motile cilium
C	0031982	cellular_component	vesicle
C	0032465	biological_process	regulation of cytokinesis
C	0032991	cellular_component	protein-containing complex
C	0034704	cellular_component	calcium channel complex
C	0035458	biological_process	cellular response to interferon-beta
C	0043209	cellular_component	myelin sheath
C	0043539	molecular_function	protein serine/threonine kinase activator activity
C	0044305	cellular_component	calyx of Held
C	0044325	molecular_function	transmembrane transporter binding
C	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
C	0046872	molecular_function	metal ion binding
C	0048306	molecular_function	calcium-dependent protein binding
C	0051592	biological_process	response to calcium ion
C	0055117	biological_process	regulation of cardiac muscle contraction
C	0060291	biological_process	long-term synaptic potentiation
C	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
C	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
C	0071346	biological_process	cellular response to type II interferon
C	0072542	molecular_function	protein phosphatase activator activity
C	0097225	cellular_component	sperm midpiece
C	0097720	biological_process	calcineurin-mediated signaling
C	0098901	biological_process	regulation of cardiac muscle cell action potential
C	0099523	cellular_component	presynaptic cytosol
C	0140056	biological_process	organelle localization by membrane tethering
C	0140238	biological_process	presynaptic endocytosis
C	0141110	molecular_function	transporter inhibitor activity
C	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
C	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
C	1902494	cellular_component	catalytic complex
C	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
C	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
D	0000922	cellular_component	spindle pole
D	0002027	biological_process	regulation of heart rate
D	0005246	molecular_function	calcium channel regulator activity
D	0005509	molecular_function	calcium ion binding
D	0005513	biological_process	detection of calcium ion
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005813	cellular_component	centrosome
D	0005819	cellular_component	spindle
D	0005829	cellular_component	cytosol
D	0005876	cellular_component	spindle microtubule
D	0005886	cellular_component	plasma membrane
D	0007186	biological_process	G protein-coupled receptor signaling pathway
D	0008076	cellular_component	voltage-gated potassium channel complex
D	0010856	molecular_function	adenylate cyclase activator activity
D	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
D	0016020	cellular_component	membrane
D	0016240	biological_process	autophagosome membrane docking
D	0019855	molecular_function	calcium channel inhibitor activity
D	0019901	molecular_function	protein kinase binding
D	0021762	biological_process	substantia nigra development
D	0030017	cellular_component	sarcomere
D	0031432	molecular_function	titin binding
D	0031514	cellular_component	motile cilium
D	0031982	cellular_component	vesicle
D	0032465	biological_process	regulation of cytokinesis
D	0032991	cellular_component	protein-containing complex
D	0034704	cellular_component	calcium channel complex
D	0035458	biological_process	cellular response to interferon-beta
D	0043209	cellular_component	myelin sheath
D	0043539	molecular_function	protein serine/threonine kinase activator activity
D	0044305	cellular_component	calyx of Held
D	0044325	molecular_function	transmembrane transporter binding
D	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
D	0046872	molecular_function	metal ion binding
D	0048306	molecular_function	calcium-dependent protein binding
D	0051592	biological_process	response to calcium ion
D	0055117	biological_process	regulation of cardiac muscle contraction
D	0060291	biological_process	long-term synaptic potentiation
D	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
D	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
D	0071346	biological_process	cellular response to type II interferon
D	0072542	molecular_function	protein phosphatase activator activity
D	0097225	cellular_component	sperm midpiece
D	0097720	biological_process	calcineurin-mediated signaling
D	0098901	biological_process	regulation of cardiac muscle cell action potential
D	0099523	cellular_component	presynaptic cytosol
D	0140056	biological_process	organelle localization by membrane tethering
D	0140238	biological_process	presynaptic endocytosis
D	0141110	molecular_function	transporter inhibitor activity
D	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
D	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
D	1902494	cellular_component	catalytic complex
D	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
D	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
E	0000922	cellular_component	spindle pole
E	0002027	biological_process	regulation of heart rate
E	0005246	molecular_function	calcium channel regulator activity
E	0005509	molecular_function	calcium ion binding
E	0005513	biological_process	detection of calcium ion
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005819	cellular_component	spindle
E	0005829	cellular_component	cytosol
E	0005876	cellular_component	spindle microtubule
E	0005886	cellular_component	plasma membrane
E	0007186	biological_process	G protein-coupled receptor signaling pathway
E	0008076	cellular_component	voltage-gated potassium channel complex
E	0010856	molecular_function	adenylate cyclase activator activity
E	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
E	0016020	cellular_component	membrane
E	0016240	biological_process	autophagosome membrane docking
E	0019855	molecular_function	calcium channel inhibitor activity
E	0019901	molecular_function	protein kinase binding
E	0021762	biological_process	substantia nigra development
E	0030017	cellular_component	sarcomere
E	0031432	molecular_function	titin binding
E	0031514	cellular_component	motile cilium
E	0031982	cellular_component	vesicle
E	0032465	biological_process	regulation of cytokinesis
E	0032991	cellular_component	protein-containing complex
E	0034704	cellular_component	calcium channel complex
E	0035458	biological_process	cellular response to interferon-beta
E	0043209	cellular_component	myelin sheath
E	0043539	molecular_function	protein serine/threonine kinase activator activity
E	0044305	cellular_component	calyx of Held
E	0044325	molecular_function	transmembrane transporter binding
E	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
E	0046872	molecular_function	metal ion binding
E	0048306	molecular_function	calcium-dependent protein binding
E	0051592	biological_process	response to calcium ion
E	0055117	biological_process	regulation of cardiac muscle contraction
E	0060291	biological_process	long-term synaptic potentiation
E	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
E	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
E	0071346	biological_process	cellular response to type II interferon
E	0072542	molecular_function	protein phosphatase activator activity
E	0097225	cellular_component	sperm midpiece
E	0097720	biological_process	calcineurin-mediated signaling
E	0098901	biological_process	regulation of cardiac muscle cell action potential
E	0099523	cellular_component	presynaptic cytosol
E	0140056	biological_process	organelle localization by membrane tethering
E	0140238	biological_process	presynaptic endocytosis
E	0141110	molecular_function	transporter inhibitor activity
E	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
E	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
E	1902494	cellular_component	catalytic complex
E	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
E	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
F	0000922	cellular_component	spindle pole
F	0002027	biological_process	regulation of heart rate
F	0005246	molecular_function	calcium channel regulator activity
F	0005509	molecular_function	calcium ion binding
F	0005513	biological_process	detection of calcium ion
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005813	cellular_component	centrosome
F	0005819	cellular_component	spindle
F	0005829	cellular_component	cytosol
F	0005876	cellular_component	spindle microtubule
F	0005886	cellular_component	plasma membrane
F	0007186	biological_process	G protein-coupled receptor signaling pathway
F	0008076	cellular_component	voltage-gated potassium channel complex
F	0010856	molecular_function	adenylate cyclase activator activity
F	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
F	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
F	0016020	cellular_component	membrane
F	0016240	biological_process	autophagosome membrane docking
F	0019855	molecular_function	calcium channel inhibitor activity
F	0019901	molecular_function	protein kinase binding
F	0021762	biological_process	substantia nigra development
F	0030017	cellular_component	sarcomere
F	0031432	molecular_function	titin binding
F	0031514	cellular_component	motile cilium
F	0031982	cellular_component	vesicle
F	0032465	biological_process	regulation of cytokinesis
F	0032991	cellular_component	protein-containing complex
F	0034704	cellular_component	calcium channel complex
F	0035458	biological_process	cellular response to interferon-beta
F	0043209	cellular_component	myelin sheath
F	0043539	molecular_function	protein serine/threonine kinase activator activity
F	0044305	cellular_component	calyx of Held
F	0044325	molecular_function	transmembrane transporter binding
F	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
F	0046872	molecular_function	metal ion binding
F	0048306	molecular_function	calcium-dependent protein binding
F	0051592	biological_process	response to calcium ion
F	0055117	biological_process	regulation of cardiac muscle contraction
F	0060291	biological_process	long-term synaptic potentiation
F	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
F	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
F	0071346	biological_process	cellular response to type II interferon
F	0072542	molecular_function	protein phosphatase activator activity
F	0097225	cellular_component	sperm midpiece
F	0097720	biological_process	calcineurin-mediated signaling
F	0098901	biological_process	regulation of cardiac muscle cell action potential
F	0099523	cellular_component	presynaptic cytosol
F	0140056	biological_process	organelle localization by membrane tethering
F	0140238	biological_process	presynaptic endocytosis
F	0141110	molecular_function	transporter inhibitor activity
F	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
F	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
F	1902494	cellular_component	catalytic complex
F	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
F	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
G	0000922	cellular_component	spindle pole
G	0002027	biological_process	regulation of heart rate
G	0005246	molecular_function	calcium channel regulator activity
G	0005509	molecular_function	calcium ion binding
G	0005513	biological_process	detection of calcium ion
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005813	cellular_component	centrosome
G	0005819	cellular_component	spindle
G	0005829	cellular_component	cytosol
G	0005876	cellular_component	spindle microtubule
G	0005886	cellular_component	plasma membrane
G	0007186	biological_process	G protein-coupled receptor signaling pathway
G	0008076	cellular_component	voltage-gated potassium channel complex
G	0010856	molecular_function	adenylate cyclase activator activity
G	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
G	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
G	0016020	cellular_component	membrane
G	0016240	biological_process	autophagosome membrane docking
G	0019855	molecular_function	calcium channel inhibitor activity
G	0019901	molecular_function	protein kinase binding
G	0021762	biological_process	substantia nigra development
G	0030017	cellular_component	sarcomere
G	0031432	molecular_function	titin binding
G	0031514	cellular_component	motile cilium
G	0031982	cellular_component	vesicle
G	0032465	biological_process	regulation of cytokinesis
G	0032991	cellular_component	protein-containing complex
G	0034704	cellular_component	calcium channel complex
G	0035458	biological_process	cellular response to interferon-beta
G	0043209	cellular_component	myelin sheath
G	0043539	molecular_function	protein serine/threonine kinase activator activity
G	0044305	cellular_component	calyx of Held
G	0044325	molecular_function	transmembrane transporter binding
G	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
G	0046872	molecular_function	metal ion binding
G	0048306	molecular_function	calcium-dependent protein binding
G	0051592	biological_process	response to calcium ion
G	0055117	biological_process	regulation of cardiac muscle contraction
G	0060291	biological_process	long-term synaptic potentiation
G	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
G	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
G	0071346	biological_process	cellular response to type II interferon
G	0072542	molecular_function	protein phosphatase activator activity
G	0097225	cellular_component	sperm midpiece
G	0097720	biological_process	calcineurin-mediated signaling
G	0098901	biological_process	regulation of cardiac muscle cell action potential
G	0099523	cellular_component	presynaptic cytosol
G	0140056	biological_process	organelle localization by membrane tethering
G	0140238	biological_process	presynaptic endocytosis
G	0141110	molecular_function	transporter inhibitor activity
G	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
G	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
G	1902494	cellular_component	catalytic complex
G	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
G	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
H	0000922	cellular_component	spindle pole
H	0002027	biological_process	regulation of heart rate
H	0005246	molecular_function	calcium channel regulator activity
H	0005509	molecular_function	calcium ion binding
H	0005513	biological_process	detection of calcium ion
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005813	cellular_component	centrosome
H	0005819	cellular_component	spindle
H	0005829	cellular_component	cytosol
H	0005876	cellular_component	spindle microtubule
H	0005886	cellular_component	plasma membrane
H	0007186	biological_process	G protein-coupled receptor signaling pathway
H	0008076	cellular_component	voltage-gated potassium channel complex
H	0010856	molecular_function	adenylate cyclase activator activity
H	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
H	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
H	0016020	cellular_component	membrane
H	0016240	biological_process	autophagosome membrane docking
H	0019855	molecular_function	calcium channel inhibitor activity
H	0019901	molecular_function	protein kinase binding
H	0021762	biological_process	substantia nigra development
H	0030017	cellular_component	sarcomere
H	0031432	molecular_function	titin binding
H	0031514	cellular_component	motile cilium
H	0031982	cellular_component	vesicle
H	0032465	biological_process	regulation of cytokinesis
H	0032991	cellular_component	protein-containing complex
H	0034704	cellular_component	calcium channel complex
H	0035458	biological_process	cellular response to interferon-beta
H	0043209	cellular_component	myelin sheath
H	0043539	molecular_function	protein serine/threonine kinase activator activity
H	0044305	cellular_component	calyx of Held
H	0044325	molecular_function	transmembrane transporter binding
H	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
H	0046872	molecular_function	metal ion binding
H	0048306	molecular_function	calcium-dependent protein binding
H	0051592	biological_process	response to calcium ion
H	0055117	biological_process	regulation of cardiac muscle contraction
H	0060291	biological_process	long-term synaptic potentiation
H	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
H	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
H	0071346	biological_process	cellular response to type II interferon
H	0072542	molecular_function	protein phosphatase activator activity
H	0097225	cellular_component	sperm midpiece
H	0097720	biological_process	calcineurin-mediated signaling
H	0098901	biological_process	regulation of cardiac muscle cell action potential
H	0099523	cellular_component	presynaptic cytosol
H	0140056	biological_process	organelle localization by membrane tethering
H	0140238	biological_process	presynaptic endocytosis
H	0141110	molecular_function	transporter inhibitor activity
H	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
H	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
H	1902494	cellular_component	catalytic complex
H	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
H	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
I	0000922	cellular_component	spindle pole
I	0002027	biological_process	regulation of heart rate
I	0005246	molecular_function	calcium channel regulator activity
I	0005509	molecular_function	calcium ion binding
I	0005513	biological_process	detection of calcium ion
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005813	cellular_component	centrosome
I	0005819	cellular_component	spindle
I	0005829	cellular_component	cytosol
I	0005876	cellular_component	spindle microtubule
I	0005886	cellular_component	plasma membrane
I	0007186	biological_process	G protein-coupled receptor signaling pathway
I	0008076	cellular_component	voltage-gated potassium channel complex
I	0010856	molecular_function	adenylate cyclase activator activity
I	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
I	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
I	0016020	cellular_component	membrane
I	0016240	biological_process	autophagosome membrane docking
I	0019855	molecular_function	calcium channel inhibitor activity
I	0019901	molecular_function	protein kinase binding
I	0021762	biological_process	substantia nigra development
I	0030017	cellular_component	sarcomere
I	0031432	molecular_function	titin binding
I	0031514	cellular_component	motile cilium
I	0031982	cellular_component	vesicle
I	0032465	biological_process	regulation of cytokinesis
I	0032991	cellular_component	protein-containing complex
I	0034704	cellular_component	calcium channel complex
I	0035458	biological_process	cellular response to interferon-beta
I	0043209	cellular_component	myelin sheath
I	0043539	molecular_function	protein serine/threonine kinase activator activity
I	0044305	cellular_component	calyx of Held
I	0044325	molecular_function	transmembrane transporter binding
I	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
I	0046872	molecular_function	metal ion binding
I	0048306	molecular_function	calcium-dependent protein binding
I	0051592	biological_process	response to calcium ion
I	0055117	biological_process	regulation of cardiac muscle contraction
I	0060291	biological_process	long-term synaptic potentiation
I	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
I	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
I	0071346	biological_process	cellular response to type II interferon
I	0072542	molecular_function	protein phosphatase activator activity
I	0097225	cellular_component	sperm midpiece
I	0097720	biological_process	calcineurin-mediated signaling
I	0098901	biological_process	regulation of cardiac muscle cell action potential
I	0099523	cellular_component	presynaptic cytosol
I	0140056	biological_process	organelle localization by membrane tethering
I	0140238	biological_process	presynaptic endocytosis
I	0141110	molecular_function	transporter inhibitor activity
I	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
I	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
I	1902494	cellular_component	catalytic complex
I	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
I	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
J	0000922	cellular_component	spindle pole
J	0002027	biological_process	regulation of heart rate
J	0005246	molecular_function	calcium channel regulator activity
J	0005509	molecular_function	calcium ion binding
J	0005513	biological_process	detection of calcium ion
J	0005515	molecular_function	protein binding
J	0005576	cellular_component	extracellular region
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005813	cellular_component	centrosome
J	0005819	cellular_component	spindle
J	0005829	cellular_component	cytosol
J	0005876	cellular_component	spindle microtubule
J	0005886	cellular_component	plasma membrane
J	0007186	biological_process	G protein-coupled receptor signaling pathway
J	0008076	cellular_component	voltage-gated potassium channel complex
J	0010856	molecular_function	adenylate cyclase activator activity
J	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
J	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
J	0016020	cellular_component	membrane
J	0016240	biological_process	autophagosome membrane docking
J	0019855	molecular_function	calcium channel inhibitor activity
J	0019901	molecular_function	protein kinase binding
J	0021762	biological_process	substantia nigra development
J	0030017	cellular_component	sarcomere
J	0031432	molecular_function	titin binding
J	0031514	cellular_component	motile cilium
J	0031982	cellular_component	vesicle
J	0032465	biological_process	regulation of cytokinesis
J	0032991	cellular_component	protein-containing complex
J	0034704	cellular_component	calcium channel complex
J	0035458	biological_process	cellular response to interferon-beta
J	0043209	cellular_component	myelin sheath
J	0043539	molecular_function	protein serine/threonine kinase activator activity
J	0044305	cellular_component	calyx of Held
J	0044325	molecular_function	transmembrane transporter binding
J	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
J	0046872	molecular_function	metal ion binding
J	0048306	molecular_function	calcium-dependent protein binding
J	0051592	biological_process	response to calcium ion
J	0055117	biological_process	regulation of cardiac muscle contraction
J	0060291	biological_process	long-term synaptic potentiation
J	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
J	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
J	0071346	biological_process	cellular response to type II interferon
J	0072542	molecular_function	protein phosphatase activator activity
J	0097225	cellular_component	sperm midpiece
J	0097720	biological_process	calcineurin-mediated signaling
J	0098901	biological_process	regulation of cardiac muscle cell action potential
J	0099523	cellular_component	presynaptic cytosol
J	0140056	biological_process	organelle localization by membrane tethering
J	0140238	biological_process	presynaptic endocytosis
J	0141110	molecular_function	transporter inhibitor activity
J	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
J	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
J	1902494	cellular_component	catalytic complex
J	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
J	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
K	0000922	cellular_component	spindle pole
K	0002027	biological_process	regulation of heart rate
K	0005246	molecular_function	calcium channel regulator activity
K	0005509	molecular_function	calcium ion binding
K	0005513	biological_process	detection of calcium ion
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005813	cellular_component	centrosome
K	0005819	cellular_component	spindle
K	0005829	cellular_component	cytosol
K	0005876	cellular_component	spindle microtubule
K	0005886	cellular_component	plasma membrane
K	0007186	biological_process	G protein-coupled receptor signaling pathway
K	0008076	cellular_component	voltage-gated potassium channel complex
K	0010856	molecular_function	adenylate cyclase activator activity
K	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
K	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
K	0016020	cellular_component	membrane
K	0016240	biological_process	autophagosome membrane docking
K	0019855	molecular_function	calcium channel inhibitor activity
K	0019901	molecular_function	protein kinase binding
K	0021762	biological_process	substantia nigra development
K	0030017	cellular_component	sarcomere
K	0031432	molecular_function	titin binding
K	0031514	cellular_component	motile cilium
K	0031982	cellular_component	vesicle
K	0032465	biological_process	regulation of cytokinesis
K	0032991	cellular_component	protein-containing complex
K	0034704	cellular_component	calcium channel complex
K	0035458	biological_process	cellular response to interferon-beta
K	0043209	cellular_component	myelin sheath
K	0043539	molecular_function	protein serine/threonine kinase activator activity
K	0044305	cellular_component	calyx of Held
K	0044325	molecular_function	transmembrane transporter binding
K	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
K	0046872	molecular_function	metal ion binding
K	0048306	molecular_function	calcium-dependent protein binding
K	0051592	biological_process	response to calcium ion
K	0055117	biological_process	regulation of cardiac muscle contraction
K	0060291	biological_process	long-term synaptic potentiation
K	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
K	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
K	0071346	biological_process	cellular response to type II interferon
K	0072542	molecular_function	protein phosphatase activator activity
K	0097225	cellular_component	sperm midpiece
K	0097720	biological_process	calcineurin-mediated signaling
K	0098901	biological_process	regulation of cardiac muscle cell action potential
K	0099523	cellular_component	presynaptic cytosol
K	0140056	biological_process	organelle localization by membrane tethering
K	0140238	biological_process	presynaptic endocytosis
K	0141110	molecular_function	transporter inhibitor activity
K	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
K	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
K	1902494	cellular_component	catalytic complex
K	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
K	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
L	0000922	cellular_component	spindle pole
L	0002027	biological_process	regulation of heart rate
L	0005246	molecular_function	calcium channel regulator activity
L	0005509	molecular_function	calcium ion binding
L	0005513	biological_process	detection of calcium ion
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005813	cellular_component	centrosome
L	0005819	cellular_component	spindle
L	0005829	cellular_component	cytosol
L	0005876	cellular_component	spindle microtubule
L	0005886	cellular_component	plasma membrane
L	0007186	biological_process	G protein-coupled receptor signaling pathway
L	0008076	cellular_component	voltage-gated potassium channel complex
L	0010856	molecular_function	adenylate cyclase activator activity
L	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
L	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
L	0016020	cellular_component	membrane
L	0016240	biological_process	autophagosome membrane docking
L	0019855	molecular_function	calcium channel inhibitor activity
L	0019901	molecular_function	protein kinase binding
L	0021762	biological_process	substantia nigra development
L	0030017	cellular_component	sarcomere
L	0031432	molecular_function	titin binding
L	0031514	cellular_component	motile cilium
L	0031982	cellular_component	vesicle
L	0032465	biological_process	regulation of cytokinesis
L	0032991	cellular_component	protein-containing complex
L	0034704	cellular_component	calcium channel complex
L	0035458	biological_process	cellular response to interferon-beta
L	0043209	cellular_component	myelin sheath
L	0043539	molecular_function	protein serine/threonine kinase activator activity
L	0044305	cellular_component	calyx of Held
L	0044325	molecular_function	transmembrane transporter binding
L	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
L	0046872	molecular_function	metal ion binding
L	0048306	molecular_function	calcium-dependent protein binding
L	0051592	biological_process	response to calcium ion
L	0055117	biological_process	regulation of cardiac muscle contraction
L	0060291	biological_process	long-term synaptic potentiation
L	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
L	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
L	0071346	biological_process	cellular response to type II interferon
L	0072542	molecular_function	protein phosphatase activator activity
L	0097225	cellular_component	sperm midpiece
L	0097720	biological_process	calcineurin-mediated signaling
L	0098901	biological_process	regulation of cardiac muscle cell action potential
L	0099523	cellular_component	presynaptic cytosol
L	0140056	biological_process	organelle localization by membrane tethering
L	0140238	biological_process	presynaptic endocytosis
L	0141110	molecular_function	transporter inhibitor activity
L	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
L	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
L	1902494	cellular_component	catalytic complex
L	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
L	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 201

Chain	Residue
A	ASP93
A	ASP95
A	ASN97
A	TYR99
A	GLU104

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 202

Chain	Residue
A	ASN137
A	GLU140
A	ASP129
A	ASP131
A	ASP133
A	GLN135

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 203

Chain	Residue
A	ASP20
A	ASP22
A	ASP24
A	THR26
A	THR28
A	GLU31

---

site_id	AC4
Number of Residues	5
Details	binding site for residue CA A 204

Chain	Residue
A	ASP56
A	ASP58
A	ASN60
A	THR62
A	GLU67

---

site_id	AC5
Number of Residues	5
Details	binding site for residue CA B 201

Chain	Residue
I	ASP20
I	ASP22
I	ASP24
I	THR26
I	GLU31

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CA B 202

Chain	Residue
B	ASP129
B	ASP131
B	ASP133
B	GLN135
B	GLU140

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CA B 203

Chain	Residue
B	ASP20
B	ASP22
B	ASP24
B	THR26
B	GLU31

---

site_id	AC8
Number of Residues	5
Details	binding site for residue CA B 204

Chain	Residue
B	ASP56
B	ASP58
B	ASN60
B	THR62
B	GLU67

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CA B 205

Chain	Residue
B	ASP93
B	ASP95
B	ASN97
B	TYR99
B	GLU104

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CA C 201

Chain	Residue
C	ASP20
C	ASP22
C	ASP24
C	THR26
C	THR28
C	GLU31

---

site_id	AD2
Number of Residues	5
Details	binding site for residue CA C 202

Chain	Residue
C	ASP58
C	ASN60
C	THR62
C	ASP64
C	GLU67

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CA D 201

Chain	Residue
D	ASP129
D	ASP131
D	ASP133
D	GLN135
D	ASN137
D	GLU140

---

site_id	AD4
Number of Residues	6
Details	binding site for residue CA D 202

Chain	Residue
D	ASP93
D	ASP95
D	GLY96
D	ASN97
D	TYR99
D	GLU104

---

site_id	AD5
Number of Residues	6
Details	binding site for residue CA E 201

Chain	Residue
E	ASP129
E	ASP131
E	ASP133
E	GLN135
E	ASN137
E	GLU140

---

site_id	AD6
Number of Residues	5
Details	binding site for residue CA E 202

Chain	Residue
E	ASP93
E	ASP95
E	ASN97
E	TYR99
E	GLU104

---

site_id	AD7
Number of Residues	5
Details	binding site for residue CA F 201

Chain	Residue
F	ASP20
F	ASP22
F	ASP24
F	THR26
F	GLU31

---

site_id	AD8
Number of Residues	5
Details	binding site for residue CA F 202

Chain	Residue
F	ASP129
F	ASP131
F	ASP133
F	GLN135
F	GLU140

---

site_id	AD9
Number of Residues	6
Details	binding site for residue CA G 201

Chain	Residue
G	ASP129
G	ASP131
G	ASP133
G	GLN135
G	ASN137
G	GLU140

---

site_id	AE1
Number of Residues	5
Details	binding site for residue CA G 202

Chain	Residue
G	ASN97
G	TYR99
G	GLU104
G	ASP93
G	ASP95

---

site_id	AE2
Number of Residues	6
Details	binding site for residue CA H 201

Chain	Residue
H	ALA128
H	ILE130
H	ASP131
H	ASP133
H	GLN135
H	GLU140

---

site_id	AE3
Number of Residues	5
Details	binding site for residue CA H 202

Chain	Residue
H	ASP93
H	ASP95
H	ASN97
H	TYR99
H	GLU104

---

site_id	AE4
Number of Residues	5
Details	binding site for residue CA I 201

Chain	Residue
I	ASP93
I	ASP95
I	ASN97
I	TYR99
I	GLU104

---

site_id	AE5
Number of Residues	5
Details	binding site for residue CA I 202

Chain	Residue
I	ASP56
I	ASP58
I	ASN60
I	THR62
I	GLU67

---

site_id	AE6
Number of Residues	6
Details	binding site for residue CA J 201

Chain	Residue
J	ASP129
J	ASP131
J	ASP133
J	GLN135
J	ASN137
J	GLU140

---

site_id	AE7
Number of Residues	5
Details	binding site for residue CA J 202

Chain	Residue
J	ASP93
J	ASP95
J	ASN97
J	TYR99
J	GLU104

---

site_id	AE8
Number of Residues	5
Details	binding site for residue CA K 201

Chain	Residue
K	ASP20
K	ASP22
K	ASP24
K	THR26
K	GLU31

---

site_id	AE9
Number of Residues	5
Details	binding site for residue CA K 202

Chain	Residue
K	ASP56
K	ASP58
K	ASN60
K	THR62
K	GLU67

---

site_id	AF1
Number of Residues	5
Details	binding site for residue CA K 203

Chain	Residue
K	ASP93
K	ASP95
K	ASN97
K	TYR99
K	GLU104

---

site_id	AF2
Number of Residues	5
Details	binding site for residue CA L 201

Chain	Residue
L	ASP20
L	ASP22
L	ASP24
L	THR26
L	GLU31

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL

Chain	Residue	Details
A	ASP20-LEU32
A	ASP56-PHE68
A	ASP93-LEU105
A	ASP129-PHE141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	315
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	320
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	120
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1474585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25441029","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27564677","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4V0C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J03","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1474585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27564677","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29724949","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CNN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CNO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1474585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27564677","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J03","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Modified residue: {"description":"Phosphothreonine; by CaMK4","evidences":[{"source":"UniProtKB","id":"P0DP29","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	12
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	12
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	12
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	12
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	24
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"UniProtKB","id":"P62157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	70
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	35
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---