6YN7
Crystal Structure of AHE enzyme from Alicyclobacillus herbarius
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008422 | molecular_function | beta-glucosidase activity |
| A | 0030245 | biological_process | cellulose catabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008422 | molecular_function | beta-glucosidase activity |
| B | 0030245 | biological_process | cellulose catabolic process |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0008422 | molecular_function | beta-glucosidase activity |
| C | 0030245 | biological_process | cellulose catabolic process |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0008422 | molecular_function | beta-glucosidase activity |
| D | 0030245 | biological_process | cellulose catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | PHE8 |
| A | GLN10 |
| A | HIS446 |
| A | GLN449 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | HIS110 |
| A | ASP157 |
| A | GLY158 |
| A | ASP160 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ARG62 |
| A | TYR63 |
| A | ARG64 |
| A | GLU65 |
| C | ARG64 |
| A | HIS61 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | HIS185 |
| A | ASP187 |
| A | GLU190 |
| A | HOH624 |
| B | GLN127 |
| B | HIS185 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | ILE290 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLU253 |
| A | ARG258 |
| A | HOH607 |
| C | ARG258 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | PHE117 |
| A | ASP160 |
| A | GLN217 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue NI A 509 |
| Chain | Residue |
| A | GLU29 |
| A | HIS61 |
| C | GLU29 |
| C | HIS61 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue PGE A 510 |
| Chain | Residue |
| A | VAL180 |
| A | HOH643 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| A | ASP276 |
| B | GLN127 |
| B | ASP131 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | VAL27 |
| B | HIS28 |
| B | ARG32 |
| B | ASP38 |
| B | HOH637 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | HIS110 |
| B | GLY158 |
| B | ASP160 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue NI B 504 |
| Chain | Residue |
| B | GLU29 |
| B | HIS61 |
| D | GLU29 |
| D | HIS61 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue PGE B 505 |
| Chain | Residue |
| B | TRP342 |
| B | SER345 |
| D | EDO501 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue PEG B 506 |
| Chain | Residue |
| B | ARG249 |
| B | GLU253 |
| B | ARG258 |
| B | GLY259 |
| B | TYR260 |
| B | PRO261 |
| B | GLN262 |
| D | ARG258 |
| D | HOH633 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | EDO502 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | VAL27 |
| C | HIS28 |
| C | ARG32 |
| C | GLY33 |
| C | GLU34 |
| C | EDO501 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | GLU72 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| C | GLU167 |
| C | GLU356 |
| C | GLU409 |
| C | HOH607 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 505 |
| Chain | Residue |
| C | GLU34 |
| C | ARG39 |
| C | GLU90 |
| C | GLN127 |
| C | ASP131 |
| D | ASP276 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 501 |
| Chain | Residue |
| B | PGE505 |
| D | ARG258 |
| D | GLN344 |
| D | SER345 |
| D | VAL346 |
| D | GLY348 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| D | VAL27 |
| D | HIS28 |
| D | ARG32 |
| D | GLU34 |
| D | EDO503 |
| site_id | AE5 |
| Number of Residues | 1 |
| Details | binding site for residue EDO D 503 |
| Chain | Residue |
| D | EDO502 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 504 |
| Chain | Residue |
| D | ASP157 |
| D | ASP160 |
| site_id | AE7 |
| Number of Residues | 1 |
| Details | binding site for residue EDO D 505 |
| Chain | Residue |
| D | ASP11 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 507 |
| Chain | Residue |
| D | GLU167 |
| D | TYR298 |
| D | GLU356 |
| D | GLU409 |
| D | HOH604 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 508 |
| Chain | Residue |
| C | ASP276 |
| D | GLU90 |
| D | GLN127 |
| D | ASP131 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 509 |
| Chain | Residue |
| D | GLU107 |
| D | ARG154 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 510 |
| Chain | Residue |
| D | HIS181 |
| D | ALA411 |
Functional Information from PROSITE/UniProt
| site_id | PS00572 |
| Number of Residues | 9 |
| Details | GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. LYITENGAA |
| Chain | Residue | Details |
| A | LEU352-ALA360 |
| site_id | PS00653 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlFGtAtASYQiEgA |
| Chain | Residue | Details |
| A | PHE12-ALA26 |
