6YGA
Crystal structure of the apo NatC complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006474 | biological_process | N-terminal protein amino acid acetylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0017196 | biological_process | N-terminal peptidyl-methionine acetylation |
| A | 0031417 | cellular_component | NatC complex |
| A | 0032880 | biological_process | regulation of protein localization |
| A | 0120518 | molecular_function | protein N-terminal-methionine acetyltransferase activity |
| B | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006474 | biological_process | N-terminal protein amino acid acetylation |
| B | 0016236 | biological_process | macroautophagy |
| B | 0017196 | biological_process | N-terminal peptidyl-methionine acetylation |
| B | 0031417 | cellular_component | NatC complex |
| C | 0003723 | molecular_function | RNA binding |
| C | 0031417 | cellular_component | NatC complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 202 |
| Chain | Residue |
| A | LYS139 |
| A | LYS153 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 203 |
| Chain | Residue |
| A | ARG78 |
| A | GLU114 |
| A | MSE138 |
| A | ILE155 |
| A | PEG204 |
| B | LEU585 |
| B | EDO818 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 204 |
| Chain | Residue |
| A | HIS72 |
| A | ARG73 |
| A | PEG203 |
| B | LYS588 |
| B | EDO818 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 205 |
| Chain | Residue |
| A | TYR144 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 206 |
| Chain | Residue |
| A | MSE1 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 207 |
| Chain | Residue |
| A | MSE69 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 208 |
| Chain | Residue |
| A | ILE81 |
| A | GLY82 |
| A | LEU117 |
| A | GLU118 |
| A | TYR130 |
| A | HOH314 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue IOD B 801 |
| Chain | Residue |
| A | ARG140 |
| B | ARG408 |
| B | GLN409 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 802 |
| Chain | Residue |
| B | PHE461 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 803 |
| Chain | Residue |
| B | GLU119 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 804 |
| Chain | Residue |
| B | THR107 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 805 |
| Chain | Residue |
| B | SER420 |
| B | EDO812 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 806 |
| Chain | Residue |
| B | GLN282 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 807 |
| Chain | Residue |
| B | THR157 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 808 |
| Chain | Residue |
| B | THR628 |
| B | VAL691 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 809 |
| Chain | Residue |
| B | PRO267 |
| B | PHE271 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 811 |
| Chain | Residue |
| B | SER465 |
| B | ASN568 |
| B | GLN605 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 812 |
| Chain | Residue |
| B | GLU388 |
| B | ASP643 |
| B | LYS677 |
| B | LYS681 |
| B | IOD805 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 813 |
| Chain | Residue |
| B | PHE170 |
| B | ASN399 |
| B | ARG406 |
| B | GLN409 |
| B | GLY410 |
| B | HOH967 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 814 |
| Chain | Residue |
| B | LYS541 |
| B | ASN544 |
| B | ILE545 |
| B | SER548 |
| B | GLU634 |
| B | ASN637 |
| B | SER641 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 815 |
| Chain | Residue |
| B | GLY167 |
| B | ILE168 |
| B | VAL169 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 816 |
| Chain | Residue |
| B | GLN360 |
| B | LEU363 |
| B | LEU364 |
| B | LYS367 |
| B | PRO374 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 817 |
| Chain | Residue |
| B | SER58 |
| B | PRO285 |
| B | LYS287 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 818 |
| Chain | Residue |
| A | PEG203 |
| A | PEG204 |
| B | ASN412 |
| B | PRO589 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 820 |
| Chain | Residue |
| B | GLU542 |
| B | ILE545 |
| B | THR546 |
| B | TYR672 |
| B | LEU676 |
| B | EDO824 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 821 |
| Chain | Residue |
| B | LYS547 |
| B | SER548 |
| B | GLU634 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 822 |
| Chain | Residue |
| B | VAL689 |
| B | ASN692 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 823 |
| Chain | Residue |
| A | MSE138 |
| B | ARG408 |
| B | ARG586 |
| B | PRO589 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 824 |
| Chain | Residue |
| B | LYS325 |
| B | PHE326 |
| B | LYS329 |
| B | GLU542 |
| B | EDO820 |
| B | HOH936 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 825 |
| Chain | Residue |
| B | HIS365 |
| B | PHE369 |
| B | TRP436 |
