Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | THR201 |
| A | DMS511 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | ARG156 |
| A | TYR247 |
| A | ASN388 |
| A | GLU392 |
| A | HOH687 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | LYS244 |
| A | HOH674 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | HIS160 |
| A | VAL161 |
| A | LEU214 |
| A | HOH725 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | THR158 |
| A | HIS160 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | LYS223 |
| A | GLY334 |
| A | GLN335 |
| A | PHE336 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | MET142 |
| A | GLY216 |
| A | THR217 |
| A | LYS221 |
| A | 8E8514 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | LYS252 |
| A | HIS253 |
| A | GLY254 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 509 |
| Chain | Residue |
| A | ARG270 |
| A | GLY271 |
| A | VAL404 |
| A | ASP405 |
| A | VAL406 |
| A | ALA407 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 510 |
| Chain | Residue |
| A | GLY120 |
| A | ALA131 |
| A | GLU132 |
| A | LEU136 |
| A | PHE202 |
| A | 1E8513 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 511 |
| Chain | Residue |
| A | THR123 |
| A | LEU187 |
| A | CYS198 |
| A | PHE199 |
| A | GLY200 |
| A | EDO501 |
| A | HOH707 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 512 |
| Chain | Residue |
| A | PRO231 |
| A | GLU232 |
| A | MET363 |
| A | GLY364 |
| A | HOH718 |
| A | HOH742 |
| site_id | AD4 |
| Number of Residues | 13 |
| Details | binding site for residue 1E8 A 513 |
| Chain | Residue |
| A | TYR121 |
| A | LEU122 |
| A | ILE133 |
| A | LEU136 |
| A | ASN138 |
| A | MET153 |
| A | GLY200 |
| A | THR201 |
| A | PHE202 |
| A | PHE209 |
| A | GLN227 |
| A | DMS510 |
| A | HOH633 |
| site_id | AD5 |
| Number of Residues | 16 |
| Details | binding site for residue 8E8 A 514 |
| Chain | Residue |
| A | MET142 |
| A | SER144 |
| A | GLY145 |
| A | LYS165 |
| A | ILE179 |
| A | ASP182 |
| A | LEU183 |
| A | MET212 |
| A | GLU213 |
| A | LEU214 |
| A | MET215 |
| A | CYS218 |
| A | LYS221 |
| A | ASP277 |
| A | PHE278 |
| A | EDO507 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ViHrDVKpsNILL |
| Chain | Residue | Details |
| A | VAL255-LEU267 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 23 |
| Details | Region: {"description":"DVD domain"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
