Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005125 | molecular_function | cytokine activity |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006954 | biological_process | inflammatory response |
| A | 0006955 | biological_process | immune response |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | GLU96 |
| A | ARG98 |
| A | HOH311 |
| A | HOH354 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SX2 A 202 |
| Chain | Residue |
| A | SX2203 |
| A | HOH346 |
| A | ASN108 |
| A | LYS109 |
| A | THR147 |
| A | MET148 |
| A | GLN149 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SX2 A 203 |
| Chain | Residue |
| A | ASP76 |
| A | LYS103 |
| A | TRP120 |
| A | GLY136 |
| A | MET148 |
| A | PHE150 |
| A | SX2202 |
Functional Information from PROSITE/UniProt
| site_id | PS00253 |
| Number of Residues | 21 |
| Details | INTERLEUKIN_1 Interleukin-1 signature. FeSAqfPnwYISTsqaenmpV |
| Chain | Residue | Details |
| A | PHE112-VAL132 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 13 |
| Details | Motif: {"description":"Involved in interaction with TMED10 C-terminus","evidences":[{"source":"PubMed","id":"32272059","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Involved in receptor binding"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Site: {"description":"Important for interaction with integrin","evidences":[{"source":"PubMed","id":"29030430","evidenceCode":"ECO:0000269"}]} |
