6Y7I
Structure of the BRD9 bromodomain and compound 2
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue OF8 A 700 |
| Chain | Residue |
| A | PHE160 |
| A | ILE169 |
| A | ASN216 |
| A | TYR222 |
| A | LYS239 |
| A | GLU240 |
| A | LEU243 |
| A | HOH829 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 701 |
| Chain | Residue |
| A | PHE163 |
| A | ARG247 |
| A | SER250 |
| A | HOH801 |
| A | HOH822 |
| A | HOH857 |
| A | ALA162 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue OF8 B 700 |
| Chain | Residue |
| B | PHE160 |
| B | PHE161 |
| B | ILE169 |
| B | ASN216 |
| B | TYR222 |
| B | HOH814 |
| B | HOH882 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding => ECO:0000269|PubMed:26365797 |
| Chain | Residue | Details |
| A | TYR222 | |
| B | ILE169 | |
| B | TYR222 | |
| A | ILE169 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q3UQU0 |
| Chain | Residue | Details |
| A | GLY172 | |
| B | GLY172 |
