6Y7I
Structure of the BRD9 bromodomain and compound 2
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue OF8 A 700 |
Chain | Residue |
A | PHE160 |
A | ILE169 |
A | ASN216 |
A | TYR222 |
A | LYS239 |
A | GLU240 |
A | LEU243 |
A | HOH829 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue EDO A 701 |
Chain | Residue |
A | PHE163 |
A | ARG247 |
A | SER250 |
A | HOH801 |
A | HOH822 |
A | HOH857 |
A | ALA162 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue OF8 B 700 |
Chain | Residue |
B | PHE160 |
B | PHE161 |
B | ILE169 |
B | ASN216 |
B | TYR222 |
B | HOH814 |
B | HOH882 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | SITE: Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding => ECO:0000269|PubMed:26365797 |
Chain | Residue | Details |
A | ILE169 | |
A | TYR222 | |
B | ILE169 | |
B | TYR222 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q3UQU0 |
Chain | Residue | Details |
A | GLY172 | |
B | GLY172 |