Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005768 | cellular_component | endosome |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006887 | biological_process | exocytosis |
| A | 0008021 | cellular_component | synaptic vesicle |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017157 | biological_process | regulation of exocytosis |
| A | 0019882 | biological_process | antigen processing and presentation |
| A | 0030742 | molecular_function | GTP-dependent protein binding |
| A | 0031489 | molecular_function | myosin V binding |
| A | 0031982 | cellular_component | vesicle |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048471 | cellular_component | perinuclear region of cytoplasm |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005768 | cellular_component | endosome |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006887 | biological_process | exocytosis |
| B | 0008021 | cellular_component | synaptic vesicle |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017157 | biological_process | regulation of exocytosis |
| B | 0019882 | biological_process | antigen processing and presentation |
| B | 0030742 | molecular_function | GTP-dependent protein binding |
| B | 0031489 | molecular_function | myosin V binding |
| B | 0031982 | cellular_component | vesicle |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048471 | cellular_component | perinuclear region of cytoplasm |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue GDP A 301 |
| Chain | Residue |
| A | SER40 |
| A | ASP146 |
| A | MET147 |
| A | SER173 |
| A | ALA174 |
| A | LYS175 |
| A | MG303 |
| A | HOH404 |
| A | HOH407 |
| A | HOH418 |
| A | VAL41 |
| A | GLY42 |
| A | LYS43 |
| A | THR44 |
| A | SER45 |
| A | PHE55 |
| A | ASN143 |
| A | LYS144 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue BTB A 302 |
| Chain | Residue |
| A | ASP146 |
| A | MET147 |
| A | GLU148 |
| A | ASP149 |
| A | GLU150 |
| B | HIS160 |
| B | GLN164 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | THR44 |
| A | GDP301 |
| A | HOH404 |
| A | HOH406 |
| A | HOH407 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue GDP B 301 |
| Chain | Residue |
| B | SER40 |
| B | VAL41 |
| B | GLY42 |
| B | LYS43 |
| B | THR44 |
| B | SER45 |
| B | PHE55 |
| B | ASN143 |
| B | LYS144 |
| B | ASP146 |
| B | MET147 |
| B | SER173 |
| B | ALA174 |
| B | LYS175 |
| B | MG303 |
| B | HOH401 |
| B | HOH405 |
| B | HOH413 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue BTB B 302 |
| Chain | Residue |
| A | HIS160 |
| A | GLN164 |
| B | ASP146 |
| B | MET147 |
| B | GLU148 |
| B | ASP149 |
| B | GLU150 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 303 |
| Chain | Residue |
| B | THR44 |
| B | GDP301 |
| B | HOH401 |
| B | HOH405 |
| B | HOH413 |
| B | HOH428 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 27 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P10949","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q63941","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Motif: {"description":"Switch 2","evidences":[{"source":"UniProtKB","id":"P10949","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by LRRK2","evidences":[{"source":"PubMed","id":"29125462","evidenceCode":"ECO:0000269"}]} |
