Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007219 | biological_process | Notch signaling pathway |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0007219 | biological_process | Notch signaling pathway |
| B | 0016567 | biological_process | protein ubiquitination |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue NAD A 701 |
| Chain | Residue |
| A | ARG530 |
| A | HIS581 |
| A | HIS582 |
| A | THR584 |
| A | HIS593 |
| A | HOH803 |
| A | HOH817 |
| A | HOH819 |
| A | HOH863 |
| A | HOH917 |
| A | HOH947 |
| A | GLY531 |
| A | HOH968 |
| A | ARG534 |
| A | SER566 |
| A | ASN567 |
| A | THR568 |
| A | THR569 |
| A | VAL576 |
| A | TRP577 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 702 |
| Chain | Residue |
| A | GLU416 |
| A | LYS525 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 703 |
| Chain | Residue |
| A | VAL403 |
| A | LYS404 |
| A | GLU436 |
| A | LEU437 |
| A | VAL438 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 704 |
| Chain | Residue |
| A | GLY476 |
| A | ASP501 |
| A | HOH901 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 705 |
| Chain | Residue |
| A | ILE492 |
| A | HOH801 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 706 |
| Chain | Residue |
| A | CYS414 |
| A | GLY423 |
| A | LYS525 |
| A | HOH802 |
| B | SER588 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 707 |
| Chain | Residue |
| A | ASP410 |
| A | CYS411 |
| A | THR412 |
| A | HIS446 |
| A | MET447 |
| A | TYR448 |
| A | THR470 |
| A | HOH826 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 708 |
| Chain | Residue |
| A | CYS411 |
| A | CYS414 |
| A | HIS449 |
| A | CYS452 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 709 |
| Chain | Residue |
| A | CYS444 |
| A | HIS446 |
| A | CYS468 |
| A | CYS471 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 702 |
| Chain | Residue |
| A | LYS431 |
| B | MET487 |
| B | HOH802 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 703 |
| Chain | Residue |
| B | LEU466 |
| B | GLN467 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 704 |
| Chain | Residue |
| B | CYS444 |
| B | HIS446 |
| B | CYS468 |
| B | CYS471 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 705 |
| Chain | Residue |
| B | CYS411 |
| B | CYS414 |
| B | HIS449 |
| B | CYS452 |
| site_id | AD5 |
| Number of Residues | 28 |
| Details | binding site for Di-peptide NAD B 701 and ASP B 501 |
| Chain | Residue |
| B | SER495 |
| B | PHE499 |
| B | PRO500 |
| B | THR502 |
| B | ARG530 |
| B | ARG530 |
| B | GLY531 |
| B | ARG534 |
| B | THR565 |
| B | SER566 |
| B | ASN567 |
| B | THR568 |
| B | VAL576 |
| B | TRP577 |
| B | HIS581 |
| B | HIS582 |
| B | THR584 |
| B | HIS593 |
| B | HOH805 |
| B | HOH806 |
| B | HOH811 |
| B | HOH826 |
| B | HOH838 |
| B | HOH863 |
| B | HOH868 |
| B | HOH868 |
| B | HOH873 |
| B | HOH883 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 122 |
| Details | Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]} |
