6Y21

Crystal structure of delta466-491 cystathionine beta-synthase from Toxoplasma gondii with L-Cystathionine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004122	molecular_function	cystathionine beta-synthase activity
A	0004124	molecular_function	cysteine synthase activity
A	0005737	cellular_component	cytoplasm
A	0006534	biological_process	cysteine metabolic process
A	0006535	biological_process	cysteine biosynthetic process from serine
A	0009069	biological_process	serine family amino acid metabolic process
A	0016829	molecular_function	lyase activity
A	0019343	biological_process	cysteine biosynthetic process via cystathionine
A	0019344	biological_process	cysteine biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0080146	molecular_function	L-cysteine desulfhydrase activity
B	0004122	molecular_function	cystathionine beta-synthase activity
B	0004124	molecular_function	cysteine synthase activity
B	0005737	cellular_component	cytoplasm
B	0006534	biological_process	cysteine metabolic process
B	0006535	biological_process	cysteine biosynthetic process from serine
B	0009069	biological_process	serine family amino acid metabolic process
B	0016829	molecular_function	lyase activity
B	0019343	biological_process	cysteine biosynthetic process via cystathionine
B	0019344	biological_process	cysteine biosynthetic process
B	0044272	biological_process	sulfur compound biosynthetic process
B	0080146	molecular_function	L-cysteine desulfhydrase activity
D	0004122	molecular_function	cystathionine beta-synthase activity
D	0004124	molecular_function	cysteine synthase activity
D	0005737	cellular_component	cytoplasm
D	0006534	biological_process	cysteine metabolic process
D	0006535	biological_process	cysteine biosynthetic process from serine
D	0009069	biological_process	serine family amino acid metabolic process
D	0016829	molecular_function	lyase activity
D	0019343	biological_process	cysteine biosynthetic process via cystathionine
D	0019344	biological_process	cysteine biosynthetic process
D	0044272	biological_process	sulfur compound biosynthetic process
D	0080146	molecular_function	L-cysteine desulfhydrase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue P1T D 601

Chain	Residue
D	LYS56
D	THR197
D	GLY243
D	ILE244
D	TYR246
D	SER287
D	PRO313
D	ASP314
D	TYR319
D	THR83
D	SER84
D	ASN86
D	THR87
D	GLN159
D	GLY193
D	THR194
D	GLY195

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site_id	AC2
Number of Residues	18
Details	binding site for residue P1T A 601

Chain	Residue
A	LYS56
A	THR83
A	SER84
A	GLY85
A	ASN86
A	THR87
A	GLN159
A	GLY193
A	THR194
A	GLY195
A	THR197
A	GLY243
A	ILE244
A	TYR246
A	SER287
A	PRO313
A	ASP314
A	TYR319

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site_id	AC3
Number of Residues	16
Details	binding site for residue P1T B 601

Chain	Residue
B	LYS56
B	THR83
B	SER84
B	ASN86
B	THR87
B	GLY193
B	THR194
B	GLY195
B	THR197
B	GLY243
B	ILE244
B	TYR246
B	SER287
B	PRO313
B	ASP314
B	TYR319

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Functional Information from PROSITE/UniProt

site_id	PS00901
Number of Residues	19
Details	CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KcEfms.AGgSVKdRiGkaM

Chain	Residue	Details
D	LYS45-MET63

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