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6Y0M

Crystal structure of human CD23 lectin domain N225D, K229E, S252N, T251N mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0002925biological_processpositive regulation of humoral immune response mediated by circulating immunoglobulin
A0005178molecular_functionintegrin binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005886cellular_componentplasma membrane
A0005887cellular_componentintegral component of plasma membrane
A0009897cellular_componentexternal side of plasma membrane
A0016020cellular_componentmembrane
A0016021cellular_componentintegral component of membrane
A0019863molecular_functionIgE binding
A0030246molecular_functioncarbohydrate binding
A0046872molecular_functionmetal ion binding
A0051000biological_processpositive regulation of nitric-oxide synthase activity
A0051712biological_processpositive regulation of killing of cells of other organism
A0051770biological_processpositive regulation of nitric-oxide synthase biosynthetic process
A0070062cellular_componentextracellular exosome
Functional Information from PROSITE/UniProt
site_idPS00615
Number of Residues24
DetailsC_TYPE_LECTIN_1 C-type lectin domain signature. CVmmrgsgr.....WNDAFCdrklgaWVC
ChainResidueDetails
ACYS259-CYS282

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues122
DetailsDomain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16765898","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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