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6XZV

Structure of zVDR LBD-Calcitriol in complex with chimera 18

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue VDX A 501
ChainResidue
ATYR175
AHIS333
AHIS423
AVAL262
ASER265
AARG302
ASER303
ASER306
ATRP314
ACYS316
AVAL328

site_idAC2
Number of Residues8
Detailsbinding site for residues G2Z B 1 and UIA B 2
ChainResidue
AGLN398
ASER431
APRO434
ASER437
AGLU446
BURL3
BMFH4
BURV5

site_idAC3
Number of Residues8
Detailsbinding site for residues UIA B 2 and URL B 3
ChainResidue
AILE270
APRO434
AGLU446
AVAL447
BG2Z1
BMFH4
BURV5
BUZN6

site_idAC4
Number of Residues10
Detailsbinding site for residues URL B 3 and O5Q B 4
ChainResidue
AHIS154
AILE270
AALA284
APRO434
AGLU446
AVAL447
BUIA2
BURV5
BUZN6
BLYS7

site_idAC5
Number of Residues9
Detailsbinding site for residues O5Q B 4 and URV B 5
ChainResidue
AHIS154
ALYS274
AALA284
APRO434
AMET438
BUIA2
BURL3
BUZN6
BLYS7

site_idAC6
Number of Residues9
Detailsbinding site for residues URV B 5 and UZN B 6
ChainResidue
ALYS274
AGLN287
ALEU291
APRO434
AMET438
BUIA2
BURL3
BMFH4
BLYS7

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:17218092, ECO:0007744|PDB:2HC4
ChainResidueDetails
ATYR175
ASER265
AARG302
ASER306
AHIS333
AHIS423

226707

PDB entries from 2024-10-30

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