Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue VDX A 501 |
| Chain | Residue |
| A | TYR175 |
| A | HIS423 |
| A | SER265 |
| A | ARG302 |
| A | SER303 |
| A | SER306 |
| A | TRP314 |
| A | CYS316 |
| A | VAL328 |
| A | HIS333 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue ACT A 502 |
| Chain | Residue |
| A | THR174 |
| A | TYR175 |
| A | ASP176 |
| A | TYR179 |
| A | TYR264 |
| A | LYS268 |
| A | ARG302 |
| A | HOH663 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 503 |
| Chain | Residue |
| A | GLN398 |
| A | SER431 |
| A | GLY449 |
| A | SER450 |
| A | HOH605 |
| A | HOH623 |
| B | GLU1 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residues UIA B 4 and URL B 5 |
| Chain | Residue |
| A | ILE288 |
| A | LYS292 |
| A | GLU446 |
| A | VAL447 |
| A | HOH646 |
| B | ASN2 |
| B | ALA3 |
| B | MFH6 |
| B | URV7 |
| B | UZN8 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residues URL B 5 and MFH B 6 |
| Chain | Residue |
| A | HIS154 |
| A | ALA284 |
| A | ILE288 |
| A | LYS292 |
| A | PRO434 |
| A | GLU446 |
| A | VAL447 |
| B | ALA3 |
| B | UIA4 |
| B | URV7 |
| B | UZN8 |
| B | LYS9 |
| B | HOH101 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residues MFH B 6 and URV B 7 |
| Chain | Residue |
| A | HIS154 |
| A | LYS274 |
| A | ALA284 |
| A | PRO434 |
| A | MET438 |
| B | ALA3 |
| B | UIA4 |
| B | URL5 |
| B | UZN8 |
| B | LYS9 |
| B | HOH101 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residues URV B 7 and UZN B 8 |
| Chain | Residue |
| A | LYS274 |
| A | GLN287 |
| A | MET438 |
| B | UIA4 |
| B | URL5 |
| B | MFH6 |
| B | LYS9 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Region: {"description":"Interaction with coactivator LXXLL motif","evidences":[{"source":"UniProtKB","id":"P13053","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Motif: {"description":"9aaTAD","evidences":[{"source":"UniProtKB","id":"P11473","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17218092","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HC4","evidenceCode":"ECO:0007744"}]} |
