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6XZK

Structure of zVDR LBD-Calcitriol in complex with chimera 13

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue VDX A 501
ChainResidue
ATYR175
AHIS423
ASER265
AARG302
ASER303
ASER306
ATRP314
ACYS316
AVAL328
AHIS333

site_idAC2
Number of Residues8
Detailsbinding site for residue ACT A 502
ChainResidue
ATHR174
ATYR175
AASP176
ATYR179
ATYR264
ALYS268
AARG302
AHOH663

site_idAC3
Number of Residues7
Detailsbinding site for residue ACT A 503
ChainResidue
AGLN398
ASER431
AGLY449
ASER450
AHOH605
AHOH623
BGLU1

site_idAC4
Number of Residues10
Detailsbinding site for residues UIA B 4 and URL B 5
ChainResidue
AILE288
ALYS292
AGLU446
AVAL447
AHOH646
BASN2
BALA3
BMFH6
BURV7
BUZN8

site_idAC5
Number of Residues13
Detailsbinding site for residues URL B 5 and MFH B 6
ChainResidue
AHIS154
AALA284
AILE288
ALYS292
APRO434
AGLU446
AVAL447
BALA3
BUIA4
BURV7
BUZN8
BLYS9
BHOH101

site_idAC6
Number of Residues11
Detailsbinding site for residues MFH B 6 and URV B 7
ChainResidue
AHIS154
ALYS274
AALA284
APRO434
AMET438
BALA3
BUIA4
BURL5
BUZN8
BLYS9
BHOH101

site_idAC7
Number of Residues7
Detailsbinding site for residues URV B 7 and UZN B 8
ChainResidue
ALYS274
AGLN287
AMET438
BUIA4
BURL5
BMFH6
BLYS9

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:17218092, ECO:0007744|PDB:2HC4
ChainResidueDetails
ATYR175
ASER265
AARG302
ASER306
AHIS333
AHIS423

226707

PDB entries from 2024-10-30

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