6XZC

CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0042802	molecular_function	identical protein binding
A	0044315	biological_process	protein secretion by the type VII secretion system
A	0051701	biological_process	biological process involved in interaction with host
A	0140321	biological_process	symbiont-mediated suppression of host autophagy
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0042802	molecular_function	identical protein binding
B	0044315	biological_process	protein secretion by the type VII secretion system
B	0051701	biological_process	biological process involved in interaction with host
B	0140321	biological_process	symbiont-mediated suppression of host autophagy
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0042802	molecular_function	identical protein binding
C	0044315	biological_process	protein secretion by the type VII secretion system
C	0051701	biological_process	biological process involved in interaction with host
C	0140321	biological_process	symbiont-mediated suppression of host autophagy
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0042802	molecular_function	identical protein binding
D	0044315	biological_process	protein secretion by the type VII secretion system
D	0051701	biological_process	biological process involved in interaction with host
D	0140321	biological_process	symbiont-mediated suppression of host autophagy
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0042802	molecular_function	identical protein binding
E	0044315	biological_process	protein secretion by the type VII secretion system
E	0051701	biological_process	biological process involved in interaction with host
E	0140321	biological_process	symbiont-mediated suppression of host autophagy
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0042802	molecular_function	identical protein binding
F	0044315	biological_process	protein secretion by the type VII secretion system
F	0051701	biological_process	biological process involved in interaction with host
F	0140321	biological_process	symbiont-mediated suppression of host autophagy
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0042802	molecular_function	identical protein binding
G	0044315	biological_process	protein secretion by the type VII secretion system
G	0051701	biological_process	biological process involved in interaction with host
G	0140321	biological_process	symbiont-mediated suppression of host autophagy

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	SITE: Cleavage; by MycP1 => ECO:0000269|PubMed:23620593, ECO:0000269|PubMed:24113528

Chain	Residue	Details
A	ALA358
E	ALA386
F	ALA358
F	ALA386
G	ALA358
G	ALA386
A	ALA386
B	ALA358
B	ALA386
C	ALA358
C	ALA386
D	ALA358
D	ALA386
E	ALA358

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site_id	SWS_FT_FI2
Number of Residues	7
Details	MOD_RES: N-acetylthreonine => ECO:0007744|PubMed:21969609

Chain	Residue	Details
A	THR2
B	THR2
C	THR2
D	THR2
E	THR2
F	THR2
G	THR2

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