6XXQ
Crystal structure of spectinomycin adenyltransferase AAD(9) from Enterococcus faecialis with ATP and spectinomycin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009012 | molecular_function | aminoglycoside 3''-adenylyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0009012 | molecular_function | aminoglycoside 3''-adenylyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 302 |
| Chain | Residue |
| A | SER35 |
| A | SER45 |
| A | ASP46 |
| A | ASP48 |
| A | ATP304 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | ASP46 |
| A | ATP304 |
| A | SCM305 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue ATP A 304 |
| Chain | Residue |
| A | SER35 |
| A | SER45 |
| A | ASP46 |
| A | ASP48 |
| A | ASP129 |
| A | ILE132 |
| A | MET133 |
| A | THR187 |
| A | ARG190 |
| A | MET191 |
| A | THR194 |
| A | LYS203 |
| A | TYR229 |
| A | MG302 |
| A | MG303 |
| A | SCM305 |
| A | GLY34 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SCM A 305 |
| Chain | Residue |
| A | TYR84 |
| A | GLU86 |
| A | TRP111 |
| A | ASP129 |
| A | ASP180 |
| A | ASN183 |
| A | MG303 |
| A | ATP304 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 302 |
| Chain | Residue |
| B | SER35 |
| B | ASP46 |
| B | ASP48 |
| B | ATP303 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue ATP B 303 |
| Chain | Residue |
| B | GLY34 |
| B | SER35 |
| B | SER45 |
| B | ASP46 |
| B | ASP48 |
| B | ASP129 |
| B | ILE132 |
| B | MET133 |
| B | GLN136 |
| B | THR187 |
| B | ARG190 |
| B | MET191 |
| B | THR194 |
| B | ILE200 |
| B | LYS203 |
| B | TYR229 |
| B | MG302 |
| B | SCM304 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SCM B 304 |
| Chain | Residue |
| B | ASP46 |
| B | GLU86 |
| B | TRP111 |
| B | MET133 |
| B | ASP180 |
| B | ASN183 |
| B | ATP303 |
