Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6XWL

Cystathionine beta-synthase from Toxoplasma gondii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004122	molecular_function	cystathionine beta-synthase activity
A	0005737	cellular_component	cytoplasm
A	0006534	biological_process	cysteine metabolic process
A	0006535	biological_process	cysteine biosynthetic process from serine
A	0009069	biological_process	serine family amino acid metabolic process
A	0016829	molecular_function	lyase activity
A	0019343	biological_process	cysteine biosynthetic process via cystathionine
A	0019344	biological_process	cysteine biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
B	0004122	molecular_function	cystathionine beta-synthase activity
B	0005737	cellular_component	cytoplasm
B	0006534	biological_process	cysteine metabolic process
B	0006535	biological_process	cysteine biosynthetic process from serine
B	0009069	biological_process	serine family amino acid metabolic process
B	0016829	molecular_function	lyase activity
B	0019343	biological_process	cysteine biosynthetic process via cystathionine
B	0019344	biological_process	cysteine biosynthetic process
B	0044272	biological_process	sulfur compound biosynthetic process
C	0004122	molecular_function	cystathionine beta-synthase activity
C	0005737	cellular_component	cytoplasm
C	0006534	biological_process	cysteine metabolic process
C	0006535	biological_process	cysteine biosynthetic process from serine
C	0009069	biological_process	serine family amino acid metabolic process
C	0016829	molecular_function	lyase activity
C	0019343	biological_process	cysteine biosynthetic process via cystathionine
C	0019344	biological_process	cysteine biosynthetic process
C	0044272	biological_process	sulfur compound biosynthetic process
D	0004122	molecular_function	cystathionine beta-synthase activity
D	0005737	cellular_component	cytoplasm
D	0006534	biological_process	cysteine metabolic process
D	0006535	biological_process	cysteine biosynthetic process from serine
D	0009069	biological_process	serine family amino acid metabolic process
D	0016829	molecular_function	lyase activity
D	0019343	biological_process	cysteine biosynthetic process via cystathionine
D	0019344	biological_process	cysteine biosynthetic process
D	0044272	biological_process	sulfur compound biosynthetic process
E	0004122	molecular_function	cystathionine beta-synthase activity
E	0005737	cellular_component	cytoplasm
E	0006534	biological_process	cysteine metabolic process
E	0006535	biological_process	cysteine biosynthetic process from serine
E	0009069	biological_process	serine family amino acid metabolic process
E	0016829	molecular_function	lyase activity
E	0019343	biological_process	cysteine biosynthetic process via cystathionine
E	0019344	biological_process	cysteine biosynthetic process
E	0044272	biological_process	sulfur compound biosynthetic process
F	0004122	molecular_function	cystathionine beta-synthase activity
F	0005737	cellular_component	cytoplasm
F	0006534	biological_process	cysteine metabolic process
F	0006535	biological_process	cysteine biosynthetic process from serine
F	0009069	biological_process	serine family amino acid metabolic process
F	0016829	molecular_function	lyase activity
F	0019343	biological_process	cysteine biosynthetic process via cystathionine
F	0019344	biological_process	cysteine biosynthetic process
F	0044272	biological_process	sulfur compound biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue PLP F 601

Chain	Residue
F	LYS56
F	ILE244
F	SER287
F	PRO313
F	ASP314
F	TYR319
F	ASN86
F	GLY191
F	GLY193
F	THR194
F	GLY195
F	THR197
F	GLU242
F	GLY243

site_id	AC2
Number of Residues	22
Details	binding site for Di-peptide PLP A 601 and LYS A 56

Chain	Residue
A	SER54
A	VAL55
A	ASP57
A	ARG58
A	ILE59
A	GLY60
A	SER84
A	ASN86
A	THR87
A	GLN159
A	GLY191
A	GLY193
A	THR194
A	GLY195
A	THR197
A	GLU242
A	GLY243
A	ILE244
A	SER287
A	PRO313
A	ASP314
A	TYR319

site_id	AC3
Number of Residues	19
Details	binding site for Di-peptide PLP B 601 and LYS B 56

Chain	Residue
B	SER54
B	VAL55
B	ASP57
B	ARG58
B	ILE59
B	GLY60
B	ASN86
B	THR87
B	GLY193
B	THR194
B	GLY195
B	THR197
B	GLU242
B	GLY243
B	ILE244
B	SER287
B	PRO313
B	ASP314
B	TYR319

site_id	AC4
Number of Residues	20
Details	binding site for Di-peptide PLP C 601 and LYS C 56

Chain	Residue
C	SER54
C	VAL55
C	ASP57
C	ARG58
C	ILE59
C	GLY60
C	ASN86
C	THR87
C	GLY191
C	GLY193
C	THR194
C	GLY195
C	THR197
C	GLU242
C	GLY243
C	ILE244
C	SER287
C	PRO313
C	ASP314
C	TYR319

site_id	AC5
Number of Residues	21
Details	binding site for Di-peptide PLP D 601 and LYS D 56

Chain	Residue
D	SER54
D	VAL55
D	ASP57
D	ARG58
D	ILE59
D	GLY60
D	SER84
D	ASN86
D	THR87
D	GLY191
D	GLY193
D	THR194
D	GLY195
D	THR197
D	GLU242
D	GLY243
D	ILE244
D	SER287
D	PRO313
D	ASP314
D	TYR319

site_id	AC6
Number of Residues	19
Details	binding site for Di-peptide PLP E 601 and LYS E 56

Chain	Residue
E	ARG58
E	ILE59
E	GLY60
E	SER84
E	ASN86
E	THR87
E	GLY193
E	THR194
E	GLY195
E	THR197
E	GLU242
E	GLY243
E	ILE244
E	SER287
E	PRO313
E	TYR319
E	SER54
E	VAL55
E	ASP57

Functional Information from PROSITE/UniProt

site_id	PS00901
Number of Residues	19
Details	CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KcEfms.AGgSVKdRiGkaM

Chain	Residue	Details
F	LYS45-MET63

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)