Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | THR203 |
| A | EDO513 |
| A | HOH642 |
| B | THR203 |
| B | GLY205 |
| B | ALA207 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| B | LYS97 |
| B | PHE315 |
| A | GLU306 |
| A | ASP310 |
| B | ASP72 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | PHE68 |
| A | PHE69 |
| A | ARG70 |
| A | LEU71 |
| A | ASP72 |
| A | TYR313 |
| A | SER314 |
| A | PHE315 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | VAL155 |
| A | ARG281 |
| A | ARG281 |
| A | GLY291 |
| A | LYS292 |
| A | HOH656 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | LEU56 |
| A | LEU85 |
| A | ILE173 |
| A | GLN181 |
| A | GLY183 |
| A | EDO508 |
| A | HOH601 |
| A | HOH632 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | ARG86 |
| A | THR164 |
| A | ARG187 |
| A | GLU191 |
| A | EDO510 |
| A | HOH611 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | LYS221 |
| A | ALA261 |
| A | HIS264 |
| A | ALA265 |
| A | HOH671 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | LEU85 |
| A | ILE173 |
| A | ASP174 |
| A | ARG187 |
| A | EDO505 |
| A | EDO510 |
| A | HOH626 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | ARG238 |
| A | LYS239 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | LYS84 |
| A | LEU85 |
| A | ARG86 |
| A | ARG187 |
| A | PHE190 |
| A | EDO506 |
| A | EDO508 |
| A | HOH601 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | ARG53 |
| A | ASP55 |
| A | GLY124 |
| A | VAL125 |
| A | ARG126 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | ARG195 |
| A | ASP284 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | THR203 |
| A | ALA207 |
| A | EDO501 |
| B | THR203 |
| B | HOH713 |
| site_id | AD5 |
| Number of Residues | 16 |
| Details | binding site for residue PLP A 514 |
| Chain | Residue |
| A | ARG77 |
| A | LYS178 |
| A | PHE185 |
| A | GLU211 |
| A | GLY214 |
| A | PHE215 |
| A | ASN216 |
| A | LEU233 |
| A | GLY235 |
| A | VAL236 |
| A | THR237 |
| A | THR272 |
| A | THR273 |
| A | HOH618 |
| A | HOH623 |
| A | HOH663 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 515 |
| Chain | Residue |
| A | THR57 |
| A | TYR58 |
| A | ASP59 |
| A | ARG77 |
| A | LEU78 |
| A | SER81 |
| A | LYS178 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 516 |
| Chain | Residue |
| A | ARG238 |
| A | HOH655 |
| A | THR227 |
| A | PRO228 |
| A | VAL232 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| B | LYS84 |
| B | LEU85 |
| B | ARG187 |
| B | PHE190 |
| B | EDO608 |
| B | HOH739 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | PRO170 |
| B | GLY171 |
| B | ASP174 |
| B | ARG187 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | TYR263 |
| B | LEU283 |
| B | LYS286 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| A | TYR309 |
| B | ASP72 |
| B | ALA312 |
| B | TYR313 |
| B | SER314 |
| B | HOH746 |
| B | HOH751 |
| B | HOH763 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| B | VAL101 |
| B | GLU316 |
| B | ILE317 |
| B | LYS318 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| B | ARG195 |
| B | ASP284 |
| site_id | AE5 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| B | SER54 |
| B | LEU56 |
| B | LEU85 |
| B | ASN179 |
| B | GLN181 |
| B | GLY183 |
| B | EDO608 |
| B | HOH736 |
| B | HOH739 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 608 |
| Chain | Residue |
| B | LEU85 |
| B | ILE173 |
| B | ASP174 |
| B | ARG187 |
| B | EDO601 |
| B | EDO607 |
| site_id | AE7 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide PLP B 609 and LYS B 178 |
| Chain | Residue |
| B | THR57 |
| B | TYR58 |
| B | ARG77 |
| B | THR176 |
| B | VAL177 |
| B | ASN179 |
| B | PHE185 |
| B | GLU211 |
| B | GLY214 |
| B | PHE215 |
| B | ASN216 |
| B | LEU233 |
| B | GLY235 |
| B | VAL236 |
| B | THR237 |
| B | THR272 |
| B | THR273 |
| B | HOH715 |
| B | HOH738 |
| B | HOH747 |
